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Defect of palpebral conjunctiva

MedGen UID:
867489
•Concept ID:
C4021868
•
Anatomical Abnormality
HPO: HP:0430011

Definition

An abnormality of the palpebral conjunctiva. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDefect of palpebral conjunctiva

Professional guidelines

PubMed

The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Ocular manifestations, complications and management of congenital ichthyoses: a new look.
Malhotra R, Hernández-Martın A, Oji V
Br J Ophthalmol 2018 May;102(5):586-592. Epub 2017 Nov 3 doi: 10.1136/bjophthalmol-2017-310615. PMID: 29101124
Dry Eye Management: Targeting the Ocular Surface Microenvironment.
Zhang X, M VJ, Qu Y, He X, Ou S, Bu J, Jia C, Wang J, Wu H, Liu Z, Li W
Int J Mol Sci 2017 Jun 29;18(7) doi: 10.3390/ijms18071398. PMID: 28661456Free PMC Article

Recent clinical studies

Etiology

Tear biomarkers in dry eye disease: Progress in the last decade.
Kumar NR, Praveen M, Narasimhan R, Khamar P, D'Souza S, Sinha-Roy A, Sethu S, Shetty R, Ghosh A
Indian J Ophthalmol 2023 Apr;71(4):1190-1202. doi: 10.4103/IJO.IJO_2981_22. PMID: 37026250Free PMC Article
Non-canonical Wnt signaling in the eye.
Shah R, Amador C, Chun ST, Ghiam S, Saghizadeh M, Kramerov AA, Ljubimov AV
Prog Retin Eye Res 2023 Jul;95:101149. Epub 2022 Nov 25 doi: 10.1016/j.preteyeres.2022.101149. PMID: 36443219Free PMC Article
Biomarkers in the Occurrence and Development of Pterygium.
He S, Wu Z
Ophthalmic Res 2022;65(5):481-492. Epub 2022 Apr 11 doi: 10.1159/000523878. PMID: 35405677
Descemetocele.
Agarwal R, Nagpal R, Todi V, Sharma N
Surv Ophthalmol 2021 Jan-Feb;66(1):2-19. Epub 2020 Oct 13 doi: 10.1016/j.survophthal.2020.10.004. PMID: 33058926
Odontogenic orbital inflammation.
Costan VV, Bogdănici CM, Gheorghe L, Obadă O, Budacu C, Grigoraș C, Andronic DG, Niagu IA
Rom J Ophthalmol 2020 Apr-Jun;64(2):116-121. PMID: 32685776Free PMC Article

Diagnosis

Biomarkers in the Occurrence and Development of Pterygium.
He S, Wu Z
Ophthalmic Res 2022;65(5):481-492. Epub 2022 Apr 11 doi: 10.1159/000523878. PMID: 35405677
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function.
Nyström EEL, Martinez-Abad B, Arike L, Birchenough GMH, Nonnecke EB, Castillo PA, Svensson F, Bevins CL, Hansson GC, Johansson MEV
Science 2021 Apr 16;372(6539) doi: 10.1126/science.abb1590. PMID: 33859001Free PMC Article
Descemetocele.
Agarwal R, Nagpal R, Todi V, Sharma N
Surv Ophthalmol 2021 Jan-Feb;66(1):2-19. Epub 2020 Oct 13 doi: 10.1016/j.survophthal.2020.10.004. PMID: 33058926
Dry Eye Management: Targeting the Ocular Surface Microenvironment.
Zhang X, M VJ, Qu Y, He X, Ou S, Bu J, Jia C, Wang J, Wu H, Liu Z, Li W
Int J Mol Sci 2017 Jun 29;18(7) doi: 10.3390/ijms18071398. PMID: 28661456Free PMC Article
Diabetic complications in the cornea.
Ljubimov AV
Vision Res 2017 Oct;139:138-152. Epub 2017 Apr 28 doi: 10.1016/j.visres.2017.03.002. PMID: 28404521Free PMC Article

Therapy

Tear biomarkers in dry eye disease: Progress in the last decade.
Kumar NR, Praveen M, Narasimhan R, Khamar P, D'Souza S, Sinha-Roy A, Sethu S, Shetty R, Ghosh A
Indian J Ophthalmol 2023 Apr;71(4):1190-1202. doi: 10.4103/IJO.IJO_2981_22. PMID: 37026250Free PMC Article
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Dry Eye Management: Targeting the Ocular Surface Microenvironment.
Zhang X, M VJ, Qu Y, He X, Ou S, Bu J, Jia C, Wang J, Wu H, Liu Z, Li W
Int J Mol Sci 2017 Jun 29;18(7) doi: 10.3390/ijms18071398. PMID: 28661456Free PMC Article
Diabetic complications in the cornea.
Ljubimov AV
Vision Res 2017 Oct;139:138-152. Epub 2017 Apr 28 doi: 10.1016/j.visres.2017.03.002. PMID: 28404521Free PMC Article
Lower-eyelid blepharoplasty.
Kikkawa DO, Kim JW
Int Ophthalmol Clin 1997 Summer;37(3):163-78. doi: 10.1097/00004397-199703730-00012. PMID: 9279649

Prognosis

Biomarkers in the Occurrence and Development of Pterygium.
He S, Wu Z
Ophthalmic Res 2022;65(5):481-492. Epub 2022 Apr 11 doi: 10.1159/000523878. PMID: 35405677
Mucus fishing syndrome.
Chiew RLJ, Au Eong DTM, Au Eong KG
BMJ Case Rep 2022 Apr 8;15(4) doi: 10.1136/bcr-2022-249188. PMID: 35396241Free PMC Article
TRIM34 attenuates colon inflammation and tumorigenesis by sustaining barrier integrity.
Lian Q, Yan S, Yin Q, Yan C, Zheng W, Gu W, Zhao X, Fan W, Li X, Ma L, Ling Z, Zhang Y, Liu J, Li J, Sun B
Cell Mol Immunol 2021 Feb;18(2):350-362. Epub 2020 Feb 24 doi: 10.1038/s41423-020-0366-2. PMID: 32094504Free PMC Article
Odontogenic orbital inflammation.
Costan VV, Bogdănici CM, Gheorghe L, Obadă O, Budacu C, Grigoraș C, Andronic DG, Niagu IA
Rom J Ophthalmol 2020 Apr-Jun;64(2):116-121. PMID: 32685776Free PMC Article
Trachoma elimination, approaching 2020.
Diab MM, Allen RC, Gawdat TI, Saif AS
Curr Opin Ophthalmol 2018 Sep;29(5):451-457. doi: 10.1097/ICU.0000000000000504. PMID: 29965850

Clinical prediction guides

Sex Differences and Discordance Between Symptoms and Signs of Dry Eye Disease.
Lu PT, Lee CY, Sun CC
Am J Ophthalmol 2024 Apr;260:14-20. Epub 2023 Oct 14 doi: 10.1016/j.ajo.2023.10.008. PMID: 37844751
Clinical and Genetic Findings in a Series of Eight Families with Arthrogryposis.
Pollazzon M, Caraffi SG, Faccioli S, Rosato S, Fodstad H, Campos-Xavier B, Soncini E, Comitini G, Frattini D, Grimaldi T, Marinelli M, Martorana D, Percesepe A, Sassi S, Fusco C, Gargano G, Superti-Furga A, Garavelli L
Genes (Basel) 2021 Dec 23;13(1) doi: 10.3390/genes13010029. PMID: 35052370Free PMC Article
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function.
Nyström EEL, Martinez-Abad B, Arike L, Birchenough GMH, Nonnecke EB, Castillo PA, Svensson F, Bevins CL, Hansson GC, Johansson MEV
Science 2021 Apr 16;372(6539) doi: 10.1126/science.abb1590. PMID: 33859001Free PMC Article
Human papillomavirus infection and ocular surface disease (Review).
Chalkia AK, Bontzos G, Spandidos DA, Detorakis ET
Int J Oncol 2019 May;54(5):1503-1510. Epub 2019 Mar 19 doi: 10.3892/ijo.2019.4755. PMID: 30896784Free PMC Article
Surgical techniques and adjuvants for the management of primary and recurrent pterygia.
Hovanesian JA, Starr CE, Vroman DT, Mah FS, Gomes JAP, Farid M, Shamie N, Davidson RS, John T, Holland EJ, Kim T; ASCRS Cornea Clinical Committee
J Cataract Refract Surg 2017 Mar;43(3):405-419. doi: 10.1016/j.jcrs.2017.03.002. PMID: 28410726

Recent systematic reviews

Utility of photography for trachoma surveys: A systematic review.
Naufal F, West SK, Brady CJ
Surv Ophthalmol 2022 May-Jun;67(3):842-857. Epub 2021 Aug 20 doi: 10.1016/j.survophthal.2021.08.005. PMID: 34425127
Autologous Blood for Conjunctival Autograft Fixation in Primary Pterygium Surgery: A Systematic Review and Meta-analysis.
Zein H, Ismail A, Abdelmongy M, Elsherif S, Hassanen A, Muhammad B, Assaf F, Elsehili A, Negida A, Yamane S, Abdel-Daim MM, Kadonosono K
Curr Pharm Des 2018;24(35):4197-4204. doi: 10.2174/1381612824666181001161352. PMID: 30277146
Efficacy of fibrin glue versus sutures for attaching conjunctival autografts in pterygium surgery: a systematic review with meta-analysis and trial sequential analysis of evidence.
Lan A, Xiao F, Wang Y, Luo Z, Cao Q
Oncotarget 2017 Jun 20;8(25):41487-41497. doi: 10.18632/oncotarget.17195. PMID: 28489563Free PMC Article

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