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Enlarged hippocampus

MedGen UID:
867525
•Concept ID:
C4021908
•
Anatomical Abnormality
HPO: HP:0100961

Definition

Increase in size of the hippocampus. [from HPO]

Professional guidelines

PubMed

Diagnosis and surgical treatment of non-lesional temporal lobe epilepsy with unilateral amygdala enlargement.
Fan Z, Sun B, Lang LQ, Hu J, Hameed NUF, Wei ZX, Zhuang QY, Cai JJ, Liu FT, Mao YT, Feng R, Pan L
Neurol Sci 2021 Jun;42(6):2353-2361. Epub 2020 Oct 12 doi: 10.1007/s10072-020-04794-8. PMID: 33044668
SMRI Biomarkers Predict Electroconvulsive Treatment Outcomes: Accuracy with Independent Data Sets.
Jiang R, Abbott CC, Jiang T, Du Y, Espinoza R, Narr KL, Wade B, Yu Q, Song M, Lin D, Chen J, Jones T, Argyelan M, Petrides G, Sui J, Calhoun VD
Neuropsychopharmacology 2018 Apr;43(5):1078-1087. Epub 2017 Jul 31 doi: 10.1038/npp.2017.165. PMID: 28758644Free PMC Article
Neural circuits and mechanisms involved in fear generalization: Implications for the pathophysiology and treatment of posttraumatic stress disorder.
Lopresto D, Schipper P, Homberg JR
Neurosci Biobehav Rev 2016 Jan;60:31-42. Epub 2015 Oct 28 doi: 10.1016/j.neubiorev.2015.10.009. PMID: 26519776

Recent clinical studies

Etiology

Hippocampal abnormalities in malformations of cortical development: MRI study.
Kuchukhidze G, Koppelstaetter F, Unterberger I, Dobesberger J, Walser G, Zamarian L, Haberlandt E, Maier H, Ortler M, Gotwald T, Gelpi E, Czech T, Feucht M, Bauer G, Delazer M, Felber S, Trinka E
Neurology 2010 May 18;74(20):1575-82. doi: 10.1212/WNL.0b013e3181df09b6. PMID: 20479356
Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder.
Plessen KJ, Bansal R, Zhu H, Whiteman R, Amat J, Quackenbush GA, Martin L, Durkin K, Blair C, Royal J, Hugdahl K, Peterson BS
Arch Gen Psychiatry 2006 Jul;63(7):795-807. doi: 10.1001/archpsyc.63.7.795. PMID: 16818869Free PMC Article

Diagnosis

Hippocampus and amygdala morphology in attention-deficit/hyperactivity disorder.
Plessen KJ, Bansal R, Zhu H, Whiteman R, Amat J, Quackenbush GA, Martin L, Durkin K, Blair C, Royal J, Hugdahl K, Peterson BS
Arch Gen Psychiatry 2006 Jul;63(7):795-807. doi: 10.1001/archpsyc.63.7.795. PMID: 16818869Free PMC Article
Patterns of hippocampal abnormalities in malformations of cortical development.
Montenegro MA, Kinay D, Cendes F, Bernasconi A, Bernasconi N, Coan AC, Li LM, Guerreiro MM, Guerreiro CA, Lopes-Cendes I, Andermann E, Dubeau F, Andermann F
J Neurol Neurosurg Psychiatry 2006 Mar;77(3):367-71. doi: 10.1136/jnnp.2005.070417. PMID: 16484646Free PMC Article

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