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Increased female libido

MedGen UID:
868283
•Concept ID:
C4022675
•
Finding
Synonym: Increased female sex drive
 
HPO: HP:0030019

Definition

Elevated sexual desire in female [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased female libido

Professional guidelines

PubMed

Mindfulness and Management of Low Desire and Vulvovaginal Pain.
Brotto LA, Altas M
Obstet Gynecol Clin North Am 2024 Jun;51(2):273-284. Epub 2024 Mar 11 doi: 10.1016/j.ogc.2024.02.002. PMID: 38777483
Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries.
Guo Y, Zhang H, Lai H, Wang H, Chong-Neto HJ, Valle SOR, Zhu R
Orphanet J Rare Dis 2022 Nov 2;17(1):399. doi: 10.1186/s13023-022-02536-x. PMID: 36324138Free PMC Article
Testosterone therapy and other treatment modalities for female sexual dysfunction.
Ingram CF, Payne KS, Messore M, Scovell JM
Curr Opin Urol 2020 May;30(3):309-316. doi: 10.1097/MOU.0000000000000759. PMID: 32205812

Recent clinical studies

Etiology

Finasteride for hair loss: a review.
Gupta AK, Venkataraman M, Talukder M, Bamimore MA
J Dermatolog Treat 2022 Jun;33(4):1938-1946. Epub 2021 Aug 2 doi: 10.1080/09546634.2021.1959506. PMID: 34291720
Energy Availability in Athletics: Health, Performance, and Physique.
Melin AK, Heikura IA, Tenforde A, Mountjoy M
Int J Sport Nutr Exerc Metab 2019 Mar 1;29(2):152-164. Epub 2019 Feb 26 doi: 10.1123/ijsnem.2018-0201. PMID: 30632422
'PROFOX'--the post HRT nightmare.
Studd J
Climacteric 2011 Apr;14(2):217-9. Epub 2010 Nov 25 doi: 10.3109/13697137.2010.529199. PMID: 21105839
Tibolone: a review.
Albertazzi P, Di Micco R, Zanardi E
Maturitas 1998 Nov 16;30(3):295-305. doi: 10.1016/s0378-5122(98)00059-0. PMID: 9881330
Is homophobia associated with homosexual arousal?
Adams HE, Wright LW Jr, Lohr BA
J Abnorm Psychol 1996 Aug;105(3):440-5. doi: 10.1037//0021-843x.105.3.440. PMID: 8772014

Diagnosis

Evaluation of long-term efficacy and safety of dienogest in patients with chronic cyclic pelvic pain associated with endometriosis.
Maiorana A, Maranto M, Restivo V, Gerfo DL, Minneci G, Mercurio A, Incandela D
Arch Gynecol Obstet 2024 Feb;309(2):589-597. Epub 2023 Nov 29 doi: 10.1007/s00404-023-07271-7. PMID: 38019280Free PMC Article
The role of estradiol in male reproductive function.
Schulster M, Bernie AM, Ramasamy R
Asian J Androl 2016 May-Jun;18(3):435-40. doi: 10.4103/1008-682X.173932. PMID: 26908066Free PMC Article
Adrenal androgens and intracrinology.
Labrie F
Semin Reprod Med 2004 Nov;22(4):299-309. doi: 10.1055/s-2004-861547. PMID: 15635498
Androgens and the ageing male.
Juul A, Skakkebaek NE
Hum Reprod Update 2002 Sep-Oct;8(5):423-33. doi: 10.1093/humupd/8.5.423. PMID: 12398223
Is homophobia associated with homosexual arousal?
Adams HE, Wright LW Jr, Lohr BA
J Abnorm Psychol 1996 Aug;105(3):440-5. doi: 10.1037//0021-843x.105.3.440. PMID: 8772014

Therapy

Finasteride for hair loss: a review.
Gupta AK, Venkataraman M, Talukder M, Bamimore MA
J Dermatolog Treat 2022 Jun;33(4):1938-1946. Epub 2021 Aug 2 doi: 10.1080/09546634.2021.1959506. PMID: 34291720
Flibanserin: First Global Approval.
Deeks ED
Drugs 2015 Oct;75(15):1815-22. doi: 10.1007/s40265-015-0474-y. PMID: 26412054
Sexuality in women with epilepsy.
Harden CL
Epilepsy Behav 2005 Dec;7 Suppl 2:S2-6. Epub 2005 Oct 20 doi: 10.1016/j.yebeh.2005.08.025. PMID: 16243000
Hormones and sexual function.
Redmond GP
Int J Fertil Womens Med 1999 Jun-Aug;44(4):193-7. PMID: 10499740
Tibolone: a review.
Albertazzi P, Di Micco R, Zanardi E
Maturitas 1998 Nov 16;30(3):295-305. doi: 10.1016/s0378-5122(98)00059-0. PMID: 9881330

Prognosis

The effects of sexual shame, emotion regulation and gender on sexual desire.
Sævik KW, Konijnenberg C
Sci Rep 2023 Mar 10;13(1):4042. doi: 10.1038/s41598-023-31181-y. PMID: 36899212Free PMC Article
Using Emotionally Focused Therapy to Treat Sexual Desire Discrepancy in Couples.
Girard A, Woolley SR
J Sex Marital Ther 2017 Nov 17;43(8):720-735. Epub 2016 Nov 28 doi: 10.1080/0092623X.2016.1263703. PMID: 27892795
Sexual dysfunction in multiple sclerosis: A 6-year follow-up study.
Kisic-Tepavcevic D, Pekmezovic T, Trajkovic G, Stojsavljevic N, Dujmovic I, Mesaros S, Drulovic J
J Neurol Sci 2015 Nov 15;358(1-2):317-23. Epub 2015 Sep 10 doi: 10.1016/j.jns.2015.09.023. PMID: 26384617
Hormones and sexual function.
Redmond GP
Int J Fertil Womens Med 1999 Jun-Aug;44(4):193-7. PMID: 10499740
Epilepsy, sex hormones, and antiepileptic drugs.
Mattson RH, Cramer JA
Epilepsia 1985;26 Suppl 1:S40-51. doi: 10.1111/j.1528-1157.1985.tb05723.x. PMID: 3158512

Clinical prediction guides

Evaluation of long-term efficacy and safety of dienogest in patients with chronic cyclic pelvic pain associated with endometriosis.
Maiorana A, Maranto M, Restivo V, Gerfo DL, Minneci G, Mercurio A, Incandela D
Arch Gynecol Obstet 2024 Feb;309(2):589-597. Epub 2023 Nov 29 doi: 10.1007/s00404-023-07271-7. PMID: 38019280Free PMC Article
Symptoms and risk factors for long COVID in non-hospitalized adults.
Subramanian A, Nirantharakumar K, Hughes S, Myles P, Williams T, Gokhale KM, Taverner T, Chandan JS, Brown K, Simms-Williams N, Shah AD, Singh M, Kidy F, Okoth K, Hotham R, Bashir N, Cockburn N, Lee SI, Turner GM, Gkoutos GV, Aiyegbusi OL, McMullan C, Denniston AK, Sapey E, Lord JM, Wraith DC, Leggett E, Iles C, Marshall T, Price MJ, Marwaha S, Davies EH, Jackson LJ, Matthews KL, Camaradou J, Calvert M, Haroon S
Nat Med 2022 Aug;28(8):1706-1714. Epub 2022 Jul 25 doi: 10.1038/s41591-022-01909-w. PMID: 35879616Free PMC Article
Should Dehydroepiandrosterone Be Administered to Women?
Wierman ME, Kiseljak-Vassiliades K
J Clin Endocrinol Metab 2022 May 17;107(6):1679-1685. doi: 10.1210/clinem/dgac130. PMID: 35254428Free PMC Article
A sex-specific dose-response curve for testosterone: could excessive testosterone limit sexual interaction in women?
Krapf JM, Simon JA
Menopause 2017 Apr;24(4):462-470. doi: 10.1097/GME.0000000000000863. PMID: 28291031
Is homophobia associated with homosexual arousal?
Adams HE, Wright LW Jr, Lohr BA
J Abnorm Psychol 1996 Aug;105(3):440-5. doi: 10.1037//0021-843x.105.3.440. PMID: 8772014

Recent systematic reviews

Selective serotonin reuptake inhibitors for premenstrual syndrome and premenstrual dysphoric disorder.
Jespersen C, Lauritsen MP, Frokjaer VG, Schroll JB
Cochrane Database Syst Rev 2024 Aug 14;8(8):CD001396. doi: 10.1002/14651858.CD001396.pub4. PMID: 39140320Free PMC Article
Does MDMA have treatment potential in sexual dysfunction? A systematic review of outcomes across the female and male sexual response cycles.
Wexler A, Dubinskaya A, Suyama J, Komisaruk BR, Anger J, Eilber K
Sex Med Rev 2023 Dec 23;12(1):26-34. doi: 10.1093/sxmrev/qead046. PMID: 37888490
Does acupuncture improve sexual dysfunction? A systematic review.
Abdi F, Alimoradi Z, Roozbeh N, Amjadi MA, Robatjazi M
J Complement Integr Med 2023 Mar 1;20(1):1-16. Epub 2021 Oct 1 doi: 10.1515/jcim-2021-0194. PMID: 34704431
Erectile and Ejaculatory Dysfunction Associated with Use of Psychotropic Drugs: A Systematic Review.
Trinchieri M, Trinchieri M, Perletti G, Magri V, Stamatiou K, Cai T, Montanari E, Trinchieri A
J Sex Med 2021 Aug;18(8):1354-1363. Epub 2021 Jul 8 doi: 10.1016/j.jsxm.2021.05.016. PMID: 34247952
Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data.
Islam RM, Bell RJ, Green S, Page MJ, Davis SR
Lancet Diabetes Endocrinol 2019 Oct;7(10):754-766. Epub 2019 Jul 25 doi: 10.1016/S2213-8587(19)30189-5. PMID: 31353194

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