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Diffuse optic disc pallor

MedGen UID:
868476
•Concept ID:
C4022870
•
Finding
HPO: HP:0012512

Definition

A pale yellow discoloration of the entire optic disc. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse optic disc pallor

Professional guidelines

PubMed

Dominant optic atrophy. Refining the clinical diagnostic criteria in light of genetic linkage studies.
Johnston RL, Seller MJ, Behnam JT, Burdon MA, Spalton DJ
Ophthalmology 1999 Jan;106(1):123-8. doi: 10.1016/S0161-6420(99)90013-1. PMID: 9917792

Recent clinical studies

Etiology

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.
Monteiro MLR, Hokazono K, Cunha LP, Biccas Neto L
BMC Ophthalmol 2018 Oct 26;18(1):278. doi: 10.1186/s12886-018-0949-1. PMID: 30367617Free PMC Article
Frequency doubling technology perimetry in non-arteritic ischaemic optic neuropathy with altitudinal defects.
Girkin CA, McGwin G Jr, DeLeon-Ortega J
Br J Ophthalmol 2004 Oct;88(10):1274-9. doi: 10.1136/bjo.2004.046383. PMID: 15377550Free PMC Article

Diagnosis

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.
Monteiro MLR, Hokazono K, Cunha LP, Biccas Neto L
BMC Ophthalmol 2018 Oct 26;18(1):278. doi: 10.1186/s12886-018-0949-1. PMID: 30367617Free PMC Article
Frequency doubling technology perimetry in non-arteritic ischaemic optic neuropathy with altitudinal defects.
Girkin CA, McGwin G Jr, DeLeon-Ortega J
Br J Ophthalmol 2004 Oct;88(10):1274-9. doi: 10.1136/bjo.2004.046383. PMID: 15377550Free PMC Article
The optic disc in glaucoma, III: diffuse optic disc pallor with raised intraocular pressure.
Hitchings RA
Br J Ophthalmol 1978 Oct;62(10):670-5. doi: 10.1136/bjo.62.10.670. PMID: 708666Free PMC Article

Prognosis

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.
Monteiro MLR, Hokazono K, Cunha LP, Biccas Neto L
BMC Ophthalmol 2018 Oct 26;18(1):278. doi: 10.1186/s12886-018-0949-1. PMID: 30367617Free PMC Article
Ocular findings in primary hyperoxaluria.
Small KW, Letson R, Scheinman J
Arch Ophthalmol 1990 Jan;108(1):89-93. doi: 10.1001/archopht.1990.01070030095036. PMID: 2297338

Clinical prediction guides

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.
Monteiro MLR, Hokazono K, Cunha LP, Biccas Neto L
BMC Ophthalmol 2018 Oct 26;18(1):278. doi: 10.1186/s12886-018-0949-1. PMID: 30367617Free PMC Article

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