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Abnormal occipital bone morphology

MedGen UID:
868565
•Concept ID:
C4022964
•
Anatomical Abnormality
Synonym: Abnormality of the occipital bone
 
HPO: HP:0012294

Definition

Abnormality of the occipital bone of the skull. [from HPO]

Professional guidelines

PubMed

Chiari Malformation (Update on Diagnosis and Treatment).
Rosenblum JS, Pomeraniec IJ, Heiss JD
Neurol Clin 2022 May;40(2):297-307. Epub 2022 Mar 31 doi: 10.1016/j.ncl.2021.11.007. PMID: 35465876Free PMC Article
Treatment of Syndromic Craniosynostosis by Anterior and Posterior Vault Distraction Osteogenesis (A-PVDO).
Shen W, Cui J, Chen J, Yi J, Kong L, Sun B
J Craniofac Surg 2022 Mar-Apr 01;33(2):654-656. doi: 10.1097/SCS.0000000000008289. PMID: 34690305
Craniovertebral junction anomalies: diagnosis and management.
Menezes AH
Semin Pediatr Neurol 1997 Sep;4(3):209-23. doi: 10.1016/s1071-9091(97)80038-1. PMID: 9323790

Recent clinical studies

Therapy

IgG4-Related Disease of the Craniovertebral Junction.
Park BJ, Starks R, Kirby P, Menezes AH, Dlouhy BJ
World Neurosurg 2020 Feb;134:264-271. Epub 2019 Nov 8 doi: 10.1016/j.wneu.2019.10.195. PMID: 31712115
Chiari malformation type I: related conditions.
deSouza RM, Zador Z, Frim DM
Neurol Res 2011 Apr;33(3):278-84. doi: 10.1179/016164111X12962202723922. PMID: 21513648
Cyclosporin and organ specific toxicity: clinical aspects, pharmacogenetics and perspectives.
Magnasco A, Rossi A, Catarsi P, Gusmano R, Ginevri F, Perfumo F, Ghiggeri GM
Curr Clin Pharmacol 2008 Sep;3(3):166-73. doi: 10.2174/157488408785747674. PMID: 18781903
Complications of fixation to the occiput-anatomical and design implications.
Lee SC, Chen JF, Lee ST
Br J Neurosurg 2004 Dec;18(6):590-7. doi: 10.1080/02688690400022813. PMID: 15799190
Common surgical pitfalls in the skull.
Keskil S, Gözil R, Calgüner E
Surg Neurol 2003 Mar;59(3):228-31; discussion 231. doi: 10.1016/s0090-3019(02)01038-8. PMID: 12681561

Prognosis

The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.
Yahanda AT, Koueik J, Ackerman LL, Adelson PD, Albert GW, Aldana PR, Alden TD, Anderson RCE, Bauer DF, Bethel-Anderson T, Bierbrauer K, Brockmeyer DL, Chern JJ, Couture DE, Daniels DJ, Dlouhy BJ, Durham SR, Ellenbogen RG, Eskandari R, Fuchs HE, Grant GA, Graupman PC, Greene S, Greenfield JP, Gross NL, Guillaume DJ, Hankinson TC, Heuer GG, Iantosca M, Iskandar BJ, Jackson EM, Jallo GI, Johnston JM, Kaufman BA, Keating RF, Khan NR, Krieger MD, Leonard JR, Maher CO, Mangano FT, Martin J, McComb JG, McEvoy SD, Meehan T, Menezes AH, Muhlbauer MS, O'Neill BR, Olavarria G, Ragheb J, Selden NR, Shah MN, Shannon CN, Shimony JS, Smyth MD, Stone SSD, Strahle JM, Tamber MS, Torner JC, Tuite GF, Tyler-Kabara EC, Wait SD, Wellons JC, Whitehead WE, Park TS, Limbrick DD, Ahmed R
J Neurosurg Pediatr 2024 Jul 1;34(1):66-74. Epub 2024 Apr 5 doi: 10.3171/2024.1.PEDS23229. PMID: 38579359
Natural History of Chiari 1 Deformity.
Venkatakrishna SSB, McClure ME, Andronikou S
J Comput Assist Tomogr 2023 Mar-Apr 01;47(2):301-306. Epub 2022 Dec 13 doi: 10.1097/RCT.0000000000001404. PMID: 36728736
Occipital Encephalocele: Cause, Incidence, Neuroimaging and Surgical Management.
Markovic I, Bosnjakovic P, Milenkovic Z
Curr Pediatr Rev 2020;16(3):200-205. doi: 10.2174/1573396315666191018161535. PMID: 31656152Free PMC Article
Occipital condyle morphometry and incidence of condylus tertius: phylogenetic and clinical significance.
Saralaya VV, Murlimanju BV, Vaderav R, Tonse M, Prameela MD, Jiji PJ
Clin Ter 2012 Nov;163(6):479-82. PMID: 23306741
Nasal encephaloceles.
Hoving EW
Childs Nerv Syst 2000 Nov;16(10-11):702-6. doi: 10.1007/s003810000339. PMID: 11151720

Clinical prediction guides

The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.
Yahanda AT, Koueik J, Ackerman LL, Adelson PD, Albert GW, Aldana PR, Alden TD, Anderson RCE, Bauer DF, Bethel-Anderson T, Bierbrauer K, Brockmeyer DL, Chern JJ, Couture DE, Daniels DJ, Dlouhy BJ, Durham SR, Ellenbogen RG, Eskandari R, Fuchs HE, Grant GA, Graupman PC, Greene S, Greenfield JP, Gross NL, Guillaume DJ, Hankinson TC, Heuer GG, Iantosca M, Iskandar BJ, Jackson EM, Jallo GI, Johnston JM, Kaufman BA, Keating RF, Khan NR, Krieger MD, Leonard JR, Maher CO, Mangano FT, Martin J, McComb JG, McEvoy SD, Meehan T, Menezes AH, Muhlbauer MS, O'Neill BR, Olavarria G, Ragheb J, Selden NR, Shah MN, Shannon CN, Shimony JS, Smyth MD, Stone SSD, Strahle JM, Tamber MS, Torner JC, Tuite GF, Tyler-Kabara EC, Wait SD, Wellons JC, Whitehead WE, Park TS, Limbrick DD, Ahmed R
J Neurosurg Pediatr 2024 Jul 1;34(1):66-74. Epub 2024 Apr 5 doi: 10.3171/2024.1.PEDS23229. PMID: 38579359
Natural History of Chiari 1 Deformity.
Venkatakrishna SSB, McClure ME, Andronikou S
J Comput Assist Tomogr 2023 Mar-Apr 01;47(2):301-306. Epub 2022 Dec 13 doi: 10.1097/RCT.0000000000001404. PMID: 36728736
Morphology of the Occipital Bones and Foramen Magnum Resulting From Premature Minor Suture Fusion in Crouzon Syndrome.
Layton RG, Pontier JF, Bins GP, Sucher BJ, Runyan CM
Cleft Palate Craniofac J 2023 May;60(5):591-600. Epub 2022 Jan 19 doi: 10.1177/10556656211072762. PMID: 35044263
The foramen magnum in scaphocephaly.
Skadorwa T, Wierzbieniec O
Childs Nerv Syst 2022 Nov;38(11):2163-2170. Epub 2022 Aug 5 doi: 10.1007/s00381-022-05624-2. PMID: 35931858Free PMC Article
Percentile-based assessment of craniosynostosis.
Wilbrand JF, Bierther U, Nord T, Reinges M, Hahn A, Christophis P, Streckbein P, Kähling C, Howaldt HP
J Craniomaxillofac Surg 2014 Jul;42(5):634-40. Epub 2013 Sep 27 doi: 10.1016/j.jcms.2013.09.005. PMID: 24717668

Recent systematic reviews

Pathogenesis and treatment of a giant occipital bone defect with meningoencephalocele in an NF1 child: case report and review of the literature.
Antico A, Vitulli F, Rossi A, Gaggero G, Piatelli G, Consales A
Childs Nerv Syst 2024 Jan;40(1):27-39. Epub 2023 Nov 23 doi: 10.1007/s00381-023-06232-4. PMID: 37993698
Posterior Fossa Dimensions of Chiari Malformation Patients Compared with Normal Subjects: Systematic Review and Meta-Analysis.
Botelho RV, Heringer LC, Botelho PB, Lopes RA, Waisberg J
World Neurosurg 2020 Jun;138:521-529.e2. Epub 2020 Mar 7 doi: 10.1016/j.wneu.2020.02.182. PMID: 32156591
First trimester detection of fetal open spina bifida using BS/BSOB ratio.
Sirico A, Raffone A, Lanzone A, Saccone G, Travaglino A, Sarno L, Rizzo G, Zullo F, Maruotti GM
Arch Gynecol Obstet 2020 Feb;301(2):333-340. Epub 2019 Dec 24 doi: 10.1007/s00404-019-05422-3. PMID: 31875250
Dural arteriovenous fistulas of the hypoglossal canal: systematic review on imaging anatomy, clinical findings, and endovascular management.
Spittau B, Millán DS, El-Sherifi S, Hader C, Singh TP, Motschall E, Vach W, Urbach H, Meckel S
J Neurosurg 2015 Apr;122(4):883-903. Epub 2014 Nov 21 doi: 10.3171/2014.10.JNS14377. PMID: 25415064

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