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Ubiquitin-positive cerebral inclusion bodies

MedGen UID:
868651
•Concept ID:
C4023052
•
Laboratory or Test Result
HPO: HP:0012083

Definition

Nuclear or cytoplasmic aggregates that show positive staining with antibodies against ubiquitin within cells of the brain. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUbiquitin-positive cerebral inclusion bodies

Professional guidelines

PubMed

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM; Consortium for Frontotemporal Lobar Degeneration
Acta Neuropathol 2007 Jul;114(1):5-22. Epub 2007 Jun 20 doi: 10.1007/s00401-007-0237-2. PMID: 17579875Free PMC Article

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