U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal circulating lysine concentration

MedGen UID:
869237
•Concept ID:
C4023660
•
Finding
Synonym: Abnormality of lysine metabolism
 
HPO: HP:0010908

Definition

Any deviation from the normal concentration of lysine in the blood circulation. [from HPO]

Professional guidelines

PubMed

Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai VB, Sakadjian A, Puthoff TD
Pharmacotherapy 2008 Sep;28(9):1162-82. doi: 10.1592/phco.28.9.1162. PMID: 18752387

Recent clinical studies

Etiology

Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Houweling AC, Scholman KT, Wakker V, Allaart CP, Uhm JS, Mathijssen IB, Baartscheer T, Postma AV, Barnett P, Verkerk AO, Boukens BJ, Christoffels VM
Circulation 2022 Feb 22;145(8):606-619. Epub 2022 Feb 3 doi: 10.1161/CIRCULATIONAHA.121.054347. PMID: 35113653Free PMC Article
Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes.
Aubert CE, Michel PL, Gillery P, Jaisson S, Fonfrede M, Morel F, Hartemann A, Bourron O
Diabetes Metab Res Rev 2014 Nov;30(8):679-85. doi: 10.1002/dmrr.2529. PMID: 24449227
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.
Van Overmeire B, Allegaert K, Casaer A, Debauche C, Decaluwé W, Jespers A, Weyler J, Harrewijn I, Langhendries JP
Lancet 2004 Nov 27-Dec 3;364(9449):1945-9. doi: 10.1016/S0140-6736(04)17477-1. PMID: 15567010

Diagnosis

Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Houweling AC, Scholman KT, Wakker V, Allaart CP, Uhm JS, Mathijssen IB, Baartscheer T, Postma AV, Barnett P, Verkerk AO, Boukens BJ, Christoffels VM
Circulation 2022 Feb 22;145(8):606-619. Epub 2022 Feb 3 doi: 10.1161/CIRCULATIONAHA.121.054347. PMID: 35113653Free PMC Article
Serum metabolism of bradykinin and des-Arg9-bradykinin in patients with angiotensin-converting enzyme inhibitor-associated angioedema.
Blais C Jr, Rouleau JL, Brown NJ, Lepage Y, Spence D, Munoz C, Friborg J, Geadah D, Gervais N, Adam A
Immunopharmacology 1999 Sep;43(2-3):293-302. doi: 10.1016/s0162-3109(99)00133-2. PMID: 10596866

Therapy

Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai VB, Sakadjian A, Puthoff TD
Pharmacotherapy 2008 Sep;28(9):1162-82. doi: 10.1592/phco.28.9.1162. PMID: 18752387
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.
Van Overmeire B, Allegaert K, Casaer A, Debauche C, Decaluwé W, Jespers A, Weyler J, Harrewijn I, Langhendries JP
Lancet 2004 Nov 27-Dec 3;364(9449):1945-9. doi: 10.1016/S0140-6736(04)17477-1. PMID: 15567010
Serum metabolism of bradykinin and des-Arg9-bradykinin in patients with angiotensin-converting enzyme inhibitor-associated angioedema.
Blais C Jr, Rouleau JL, Brown NJ, Lepage Y, Spence D, Munoz C, Friborg J, Geadah D, Gervais N, Adam A
Immunopharmacology 1999 Sep;43(2-3):293-302. doi: 10.1016/s0162-3109(99)00133-2. PMID: 10596866

Clinical prediction guides

Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes.
Aubert CE, Michel PL, Gillery P, Jaisson S, Fonfrede M, Morel F, Hartemann A, Bourron O
Diabetes Metab Res Rev 2014 Nov;30(8):679-85. doi: 10.1002/dmrr.2529. PMID: 24449227
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Pai VB, Sakadjian A, Puthoff TD
Pharmacotherapy 2008 Sep;28(9):1162-82. doi: 10.1592/phco.28.9.1162. PMID: 18752387

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...