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Abnormal spinal meningeal morphology

MedGen UID:: 869487
•Concept ID:: C4023914
•: Anatomical Abnormality

Synonym:	Abnormality of the spinal meninges

HPO:	HP:0010303

Definition

Any abnormality of the spinal meninges, the system of membranes (dura mater, the arachnoid mater, and the pia mater) which envelops the spinal cord. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal spinal meningeal morphology

Fetal anomaly
- Congenital Systemic Disorder
  - Abnormality of the nervous system
    - Abnormal nervous system morphology
      - Morphological central nervous system abnormality
        Abnormal meningeal morphology
        Abnormal spinal meningeal morphology
        Dural ectasia
        Dural tail sign
        Empty delta sign
        Spinal meningeal diverticulum

Professional guidelines

PubMed

Spinal arachnoid cysts in adults: diagnosis and management. A single-center experience.

Fam MD, Woodroffe RW, Helland L, Noeller J, Dahdaleh NS, Menezes AH, Hitchon PW
J Neurosurg Spine 2018 Dec 1;29(6):711-719. doi: 10.3171/2018.5.SPINE1820. PMID: 30265227

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).

Tobin WO, Guo Y, Krecke KN, Parisi JE, Lucchinetti CF, Pittock SJ, Mandrekar J, Dubey D, Debruyne J, Keegan BM
Brain 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200. PMID: 29050399

Surgical management of cerebral dural arteriovenous fistulae.

Rutkowski MJ, Jian B, Lawton MT
Handb Clin Neurol 2017;143:107-116. doi: 10.1016/B978-0-444-63640-9.00010-2. PMID: 28552132

See all (27)

Recent clinical studies

Etiology

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).

Tobin WO, Guo Y, Krecke KN, Parisi JE, Lucchinetti CF, Pittock SJ, Mandrekar J, Dubey D, Debruyne J, Keegan BM
Brain 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200. PMID: 29050399

Spinal vascular malformations: treatment strategies and outcome.

Flores BC, Klinger DR, White JA, Batjer HH
Neurosurg Rev 2017 Jan;40(1):15-28. Epub 2016 Apr 13 doi: 10.1007/s10143-016-0713-z. PMID: 27075861

Neural tube defects--disorders of neurulation and related embryonic processes.

Copp AJ, Greene ND
Wiley Interdiscip Rev Dev Biol 2013 Mar-Apr;2(2):213-27. Epub 2012 May 29 doi: 10.1002/wdev.71. PMID: 24009034 Free PMC Article

Spontaneous intracranial hypotension.

Gordon N
Dev Med Child Neurol 2009 Dec;51(12):932-5. doi: 10.1111/j.1469-8749.2009.03514.x. PMID: 19909307

Coccygeal pits.

Weprin BE, Oakes WJ
Pediatrics 2000 May;105(5):E69. doi: 10.1542/peds.105.5.e69. PMID: 10799633

See all (280)

Diagnosis

CSF-Venous Fistula.

Roytman M, Salama G, Robbins MS, Chazen JL
Curr Pain Headache Rep 2021 Jan 21;25(1):5. doi: 10.1007/s11916-020-00921-4. PMID: 33475890

Spinal vascular malformations: treatment strategies and outcome.

Flores BC, Klinger DR, White JA, Batjer HH
Neurosurg Rev 2017 Jan;40(1):15-28. Epub 2016 Apr 13 doi: 10.1007/s10143-016-0713-z. PMID: 27075861

Imaging of meningitis and ventriculitis.

Mohan S, Jain KK, Arabi M, Shah GV
Neuroimaging Clin N Am 2012 Nov;22(4):557-83. Epub 2012 Sep 4 doi: 10.1016/j.nic.2012.04.003. PMID: 23122257

Spinal dural arteriovenous fistula.

Koch C
Curr Opin Neurol 2006 Feb;19(1):69-75. doi: 10.1097/01.wco.0000200547.22292.11. PMID: 16415680

MR angiography of the spine.

Bowen BC, Pattany PM
Magn Reson Imaging Clin N Am 1998 Feb;6(1):165-78. PMID: 9449747

See all (587)

Therapy

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).

Tobin WO, Guo Y, Krecke KN, Parisi JE, Lucchinetti CF, Pittock SJ, Mandrekar J, Dubey D, Debruyne J, Keegan BM
Brain 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200. PMID: 29050399

Neurosyphilis.

Berger JR, Dean D
Handb Clin Neurol 2014;121:1461-72. doi: 10.1016/B978-0-7020-4088-7.00098-5. PMID: 24365430

Neural tube defects--disorders of neurulation and related embryonic processes.

Copp AJ, Greene ND
Wiley Interdiscip Rev Dev Biol 2013 Mar-Apr;2(2):213-27. Epub 2012 May 29 doi: 10.1002/wdev.71. PMID: 24009034 Free PMC Article

Endovascular management of spinal dural arteriovenous fistulas. A review.

Sivakumar W, Zada G, Yashar P, Giannotta SL, Teitelbaum G, Larsen DW
Neurosurg Focus 2009 May;26(5):E15. doi: 10.3171/2009.2.FOCUS098. PMID: 19408993

Management of leptomeningeal malignancy.

Pentheroudakis G, Pavlidis N
Expert Opin Pharmacother 2005 Jun;6(7):1115-25. doi: 10.1517/14656566.6.7.1115. PMID: 15957966

See all (165)

Prognosis

The many faces of glioblastoma: Pictorial review of atypical imaging features.

Khandwala K, Mubarak F, Minhas K
Neuroradiol J 2021 Feb;34(1):33-41. Epub 2020 Oct 20 doi: 10.1177/1971400920965970. PMID: 33081585 Free PMC Article

Spinal vascular malformations: treatment strategies and outcome.

Flores BC, Klinger DR, White JA, Batjer HH
Neurosurg Rev 2017 Jan;40(1):15-28. Epub 2016 Apr 13 doi: 10.1007/s10143-016-0713-z. PMID: 27075861

Clinical presentation and prognostic factors of spinal dural arteriovenous fistulas: an overview.

Fugate JE, Lanzino G, Rabinstein AA
Neurosurg Focus 2012 May;32(5):E17. doi: 10.3171/2012.1.FOCUS11376. PMID: 22537126

Spinal dural arteriovenous fistula.

Koch C
Curr Opin Neurol 2006 Feb;19(1):69-75. doi: 10.1097/01.wco.0000200547.22292.11. PMID: 16415680

Leptomeningeal mycosis fungoides.

Lundberg WB, Cadman EC, Skeel RT
Cancer 1976 Nov;38(5):2149-53. doi: 10.1002/1097-0142(197611)38:5<2149::aid-cncr2820380545>3.0.co;2-a. PMID: 991128

See all (228)

Clinical prediction guides

Congenital Zika virus infection: a neuropathological review.

Chimelli L, Avvad-Portari E
Childs Nerv Syst 2018 Jan;34(1):95-99. Epub 2017 Nov 22 doi: 10.1007/s00381-017-3651-3. PMID: 29167994

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).

Tobin WO, Guo Y, Krecke KN, Parisi JE, Lucchinetti CF, Pittock SJ, Mandrekar J, Dubey D, Debruyne J, Keegan BM
Brain 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200. PMID: 29050399

Spinal vascular malformations: treatment strategies and outcome.

Flores BC, Klinger DR, White JA, Batjer HH
Neurosurg Rev 2017 Jan;40(1):15-28. Epub 2016 Apr 13 doi: 10.1007/s10143-016-0713-z. PMID: 27075861

Spinal dural arteriovenous fistulas.

Krings T, Geibprasert S
AJNR Am J Neuroradiol 2009 Apr;30(4):639-48. Epub 2009 Feb 12 doi: 10.3174/ajnr.A1485. PMID: 19213818 Free PMC Article

Coccygeal pits.

Weprin BE, Oakes WJ
Pediatrics 2000 May;105(5):E69. doi: 10.1542/peds.105.5.e69. PMID: 10799633

See all (158)

Recent systematic reviews

Fourth ventricle to spinal subarachnoid space stenting in pediatric patients with refractory syringomyelia: case series and systematic review.

Spennato P, Vitulli F, Tafuto R, Imperato A, Mirone G, Cinalli G
Neurosurg Rev 2023 Mar 11;46(1):67. doi: 10.1007/s10143-023-01972-y. PMID: 36905420

Spinal epidural capillary hemangioma: A systematic literature review and an illustrative case.

Benevello C, Laaidi A, Peeters S, Moiraghi A, Tauziede-Espariat A, Oppenheim C, Pallud J
Neurochirurgie 2022 Dec;68(6):697-701. Epub 2022 Apr 25 doi: 10.1016/j.neuchi.2022.03.004. PMID: 35477014

Outcomes following surgical versus endovascular treatment of spinal dural arteriovenous fistula: a systematic review and meta-analysis.

Goyal A, Cesare J, Lu VM, Alvi MA, Kerezoudis P, Brinjikji W, Nasr D, Lanzino G, Bydon M
J Neurol Neurosurg Psychiatry 2019 Oct;90(10):1139-1146. Epub 2019 May 29 doi: 10.1136/jnnp-2019-320648. PMID: 31142659

Infections of the spinal subdural space in children: a series of 11 contemporary cases and review of all published reports. A multinational collaborative effort.

Sandler AL, Thompson D, Goodrich JT, van Aalst J, Kolatch E, El Khashab M, Nejat F, Cornips E, Mohindra S, Gupta R, Yassari R, Daniels LB 3rd, Biswas A, Abbott R
Childs Nerv Syst 2013 Jan;29(1):105-17. Epub 2012 Sep 30 doi: 10.1007/s00381-012-1916-4. PMID: 23053357

Comparative analysis of spinal extradural arteriovenous fistulas with or without intradural venous drainage: a systematic literature review.

Takai K, Taniguchi M
Neurosurg Focus 2012 May;32(5):E8. doi: 10.3171/2012.2.FOCUS1216. PMID: 22537134

See all (6)

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Abnormal spinal meningeal morphology

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

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