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Frequent Giardia lamblia infestation

MedGen UID:
870778
Concept ID:
C4025235
Finding
HPO: HP:0005215

Definition

Increased susceptibility to Giardia lamblia infection of the intestine, as manifested by a medical history of multiple episodes of Giardia lamblia intestinal infection. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFrequent Giardia lamblia infestation

Conditions with this feature

Immunodeficiency, common variable, 10
MedGen UID:
816321
Concept ID:
C3809991
Disease or Syndrome
Common variable immunodeficiency-10 (CVID10) is an autosomal dominant primary immunodeficiency characterized by childhood-onset of recurrent infections, hypogammaglobulinemia, and decreased numbers of memory and marginal zone B cells. Some patients may develop autoimmune features and have circulating autoantibodies. An unusual feature is central adrenal insufficiency (summary by Chen et al., 2013). For a general description and a discussion of genetic heterogeneity of common variable immunodeficiency, see CVID1 (607594).

Professional guidelines

PubMed

Dashti N, Zarebavani M
Naunyn Schmiedebergs Arch Pharmacol 2021 Sep;394(9):1869-1878. Epub 2021 Jul 29 doi: 10.1007/s00210-021-02124-z. PMID: 34324017
Abu-Madi M, Boughattas S, Behnke JM, Sharma A, Ismail A
Parasit Vectors 2017 Sep 6;10(1):414. doi: 10.1186/s13071-017-2346-7. PMID: 28877704Free PMC Article
Gardner TB, Hill DR
Clin Microbiol Rev 2001 Jan;14(1):114-28. doi: 10.1128/CMR.14.1.114-128.2001. PMID: 11148005Free PMC Article

Recent clinical studies

Etiology

Hernández-Castro C, Dashti A, Vusirikala A, Balasegaram S, Köster PC, Bailo B, Imaña E, López A, Llorente MT, González-Barrio D, Sánchez S, Carmena D
Eur J Pediatr 2023 Jan;182(1):213-223. Epub 2022 Oct 25 doi: 10.1007/s00431-022-04662-x. PMID: 36282323
Li J, Wang Z, Karim MR, Zhang L
Parasit Vectors 2020 Jul 29;13(1):380. doi: 10.1186/s13071-020-04255-3. PMID: 32727529Free PMC Article
Trelis M, Taroncher-Ferrer S, Gozalbo M, Ortiz V, Soriano JM, Osuna A, Merino-Torres JF
Nutrients 2019 Dec 5;11(12) doi: 10.3390/nu11122973. PMID: 31817420Free PMC Article
Leung AKC, Leung AAM, Wong AHC, Sergi CM, Kam JKM
Recent Pat Inflamm Allergy Drug Discov 2019;13(2):134-143. doi: 10.2174/1872213X13666190618124901. PMID: 31210116
El-Badry AA, Ghieth MA, Ahmed DA, Ismail MAM
J Egypt Soc Parasitol 2017 Apr;47(1):19-24. PMID: 30157329

Diagnosis

Leung AKC, Leung AAM, Wong AHC, Sergi CM, Kam JKM
Recent Pat Inflamm Allergy Drug Discov 2019;13(2):134-143. doi: 10.2174/1872213X13666190618124901. PMID: 31210116
Gardner TB, Hill DR
Clin Microbiol Rev 2001 Jan;14(1):114-28. doi: 10.1128/CMR.14.1.114-128.2001. PMID: 11148005Free PMC Article
Marshall MM, Naumovitz D, Ortega Y, Sterling CR
Clin Microbiol Rev 1997 Jan;10(1):67-85. doi: 10.1128/CMR.10.1.67. PMID: 8993859Free PMC Article
Wolfe MS
Clin Microbiol Rev 1992 Jan;5(1):93-100. doi: 10.1128/CMR.5.1.93. PMID: 1735095Free PMC Article
Pickering LK, Engelkirk PG
Pediatr Clin North Am 1988 Jun;35(3):565-77. doi: 10.1016/s0031-3955(16)36472-0. PMID: 3287315

Therapy

Dashti N, Zarebavani M
Naunyn Schmiedebergs Arch Pharmacol 2021 Sep;394(9):1869-1878. Epub 2021 Jul 29 doi: 10.1007/s00210-021-02124-z. PMID: 34324017
Leung AKC, Leung AAM, Wong AHC, Sergi CM, Kam JKM
Recent Pat Inflamm Allergy Drug Discov 2019;13(2):134-143. doi: 10.2174/1872213X13666190618124901. PMID: 31210116
Gardner TB, Hill DR
Clin Microbiol Rev 2001 Jan;14(1):114-28. doi: 10.1128/CMR.14.1.114-128.2001. PMID: 11148005Free PMC Article
Marshall MM, Naumovitz D, Ortega Y, Sterling CR
Clin Microbiol Rev 1997 Jan;10(1):67-85. doi: 10.1128/CMR.10.1.67. PMID: 8993859Free PMC Article
Hill DR
Infect Dis Clin North Am 1993 Sep;7(3):503-25. PMID: 8254157

Prognosis

Aninagyei E, Nanga S, Acheampong DO, Mensah R, Boadu MN, Kwansa-Bentum HT, Tettey CO
BMC Infect Dis 2021 Oct 9;21(1):1047. doi: 10.1186/s12879-021-06731-2. PMID: 34627168Free PMC Article
Peters TE, Kreuels B, Addo MM, Tannich E, Rothe C
Travel Med Infect Dis 2021 Sep-Oct;43:102090. Epub 2021 Jun 1 doi: 10.1016/j.tmaid.2021.102090. PMID: 34082086
El-Badry AA, Ghieth MA, Ahmed DA, Ismail MAM
J Egypt Soc Parasitol 2017 Apr;47(1):19-24. PMID: 30157329
Gardner TB, Hill DR
Clin Microbiol Rev 2001 Jan;14(1):114-28. doi: 10.1128/CMR.14.1.114-128.2001. PMID: 11148005Free PMC Article
Fraser D, Dagan R, Naggan L, Greene V, El-On J, Abu-Rbiah Y, Deckelbaum RJ
Am J Trop Med Hyg 1997 Nov;57(5):544-9. doi: 10.4269/ajtmh.1997.57.544. PMID: 9392593

Clinical prediction guides

Hernández-Castro C, Dashti A, Vusirikala A, Balasegaram S, Köster PC, Bailo B, Imaña E, López A, Llorente MT, González-Barrio D, Sánchez S, Carmena D
Eur J Pediatr 2023 Jan;182(1):213-223. Epub 2022 Oct 25 doi: 10.1007/s00431-022-04662-x. PMID: 36282323
Dashti N, Zarebavani M
Naunyn Schmiedebergs Arch Pharmacol 2021 Sep;394(9):1869-1878. Epub 2021 Jul 29 doi: 10.1007/s00210-021-02124-z. PMID: 34324017
Trelis M, Taroncher-Ferrer S, Gozalbo M, Ortiz V, Soriano JM, Osuna A, Merino-Torres JF
Nutrients 2019 Dec 5;11(12) doi: 10.3390/nu11122973. PMID: 31817420Free PMC Article
Leung AKC, Leung AAM, Wong AHC, Sergi CM, Kam JKM
Recent Pat Inflamm Allergy Drug Discov 2019;13(2):134-143. doi: 10.2174/1872213X13666190618124901. PMID: 31210116
El-Badry AA, Ghieth MA, Ahmed DA, Ismail MAM
J Egypt Soc Parasitol 2017 Apr;47(1):19-24. PMID: 30157329

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