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Odontogenic Myxoma

MedGen UID:
87265
Concept ID:
C0334569
Neoplastic Process
Synonym: Odontogenic myxoma
SNOMED CT: Odontogenic myxoma (34941004)

Definition

An intraosseous odontogenic neoplasm with good prognosis, arising from the mandible and less frequently from the maxilla. It is characterized by the presence of stellate cells and abundant myxoid stroma formation. Small tumors may be cured with enucleation. Complete excision may be required for larger tumors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOdontogenic Myxoma

Professional guidelines

PubMed

Zhao M, Lu Y, Takata T, Ogawa I, Miyauchi M, Mock D, Nikai H
Pathol Res Pract 1999;195(6):391-7. doi: 10.1016/S0344-0338(99)80012-0. PMID: 10399179

Recent clinical studies

Etiology

Melo G, Batistella EÂ, Bett JVS, Grando LJ, Rivero ERC
Eur Arch Paediatr Dent 2023 Aug;24(4):451-459. Epub 2023 Apr 26 doi: 10.1007/s40368-023-00800-7. PMID: 37099119
Khatib B, Cheng A, Sim F, Bray B, Patel A
J Oral Maxillofac Surg 2020 Oct;78(10):1869.e1-1869.e10. Epub 2020 Jun 29 doi: 10.1016/j.joms.2020.06.007. PMID: 32707040
Aregbesola B, Soyele O, Effiom O, Gbotolorun O, Taiwo O, Amole I
Med Oral Patol Oral Cir Bucal 2018 Nov 1;23(6):e761-e766. doi: 10.4317/medoral.22473. PMID: 30341260Free PMC Article
Boffano P, Gallesio C, Barreca A, Bianchi FA, Garzino-Demo P, Roccia F
J Craniofac Surg 2011 May;22(3):982-7. doi: 10.1097/SCS.0b013e3182101400. PMID: 21558907
Kaffe I, Naor H, Buchner A
Dentomaxillofac Radiol 1997 Sep;26(5):299-303. doi: 10.1038/sj.dmfr.4600261. PMID: 9482003

Diagnosis

Velez Torres JM, Mata DA, Briski LM, Green DC, Cloutier JM, Kerr DA, Montgomery EA, Rosenberg AE
Mod Pathol 2023 Jul;36(7):100189. Epub 2023 Apr 13 doi: 10.1016/j.modpat.2023.100189. PMID: 37059229
Dotta JH, Miotto LN, Spin-Neto R, Ferrisse TM
Eur J Clin Invest 2020 Apr;50(4):e13214. Epub 2020 Mar 14 doi: 10.1111/eci.13214. PMID: 32048275
Benjelloun L, Cherradi N, Kessab A, Dghoughi S
J Stomatol Oral Maxillofac Surg 2018 Apr;119(2):154-157. Epub 2017 Dec 8 doi: 10.1016/j.jormas.2017.12.001. PMID: 29229314
Barker BF
Semin Diagn Pathol 1999 Nov;16(4):297-301. PMID: 10587272
Katz JO, Underhill TE
Dent Clin North Am 1994 Jan;38(1):63-81. PMID: 8307237

Therapy

Silva DFB, Verheul HCCRS, Agripino GG, Neto PA, Alves PM, de Melo DP, de Castro Gomes DQ
Lasers Med Sci 2023 Jan 11;38(1):38. doi: 10.1007/s10103-023-03705-5. PMID: 36630018
Bologna-Molina R, Mosqueda-Taylor A, Domínguez-Malagón H, Salazar-Rodríguez S, Tapia G, Gónzalez-Gónzalez R, Molina-Frechero N
Rom J Morphol Embryol 2015;56(2):465-73. PMID: 26193215
Martínez-Mata G, Mosqueda-Taylor A, Carlos-Bregni R, de Almeida OP, Contreras-Vidaurre E, Vargas PA, Cano-Valdéz AM, Domínguez-Malagón H
Oral Oncol 2008 Jun;44(6):601-7. Epub 2007 Nov 8 doi: 10.1016/j.oraloncology.2007.08.009. PMID: 17996487
Carlson ER, Monteleone K
J Oral Maxillofac Surg 2004 Sep;62(9):1103-7. doi: 10.1016/j.joms.2004.05.114. PMID: 15346361
Muller H, Slootweg PJ
J Craniomaxillofac Surg 1988 Jul;16(5):238-9. doi: 10.1016/s1010-5182(88)80054-4. PMID: 3165391

Prognosis

Velez Torres JM, Mata DA, Briski LM, Green DC, Cloutier JM, Kerr DA, Montgomery EA, Rosenberg AE
Mod Pathol 2023 Jul;36(7):100189. Epub 2023 Apr 13 doi: 10.1016/j.modpat.2023.100189. PMID: 37059229
Khatib B, Cheng A, Sim F, Bray B, Patel A
J Oral Maxillofac Surg 2020 Oct;78(10):1869.e1-1869.e10. Epub 2020 Jun 29 doi: 10.1016/j.joms.2020.06.007. PMID: 32707040
Kauke M, Safi AF, Kreppel M, Grandoch A, Nickenig HJ, Zöller JE, Dreiseidler T
Dentomaxillofac Radiol 2018 Feb;47(2):20170262. Epub 2017 Nov 6 doi: 10.1259/dmfr.20170262. PMID: 29082773Free PMC Article
Gomes CC, Diniz MG, Duarte AP, Bernardes VF, Gomez RS
Oral Oncol 2011 May;47(5):325-8. Epub 2011 Mar 27 doi: 10.1016/j.oraloncology.2011.03.006. PMID: 21444236
Regezi JA
Mod Pathol 2002 Mar;15(3):331-41. doi: 10.1038/modpathol.3880527. PMID: 11904346

Clinical prediction guides

Velez Torres JM, Mata DA, Briski LM, Green DC, Cloutier JM, Kerr DA, Montgomery EA, Rosenberg AE
Mod Pathol 2023 Jul;36(7):100189. Epub 2023 Apr 13 doi: 10.1016/j.modpat.2023.100189. PMID: 37059229
Souza JC, Bastos VC, Pereira NB, Dias AAM, Avelar GF, Gomez RS, Gomes CC
Int J Exp Pathol 2022 Apr;103(2):65-69. Epub 2022 Feb 28 doi: 10.1111/iep.12431. PMID: 35225401Free PMC Article
Khatib B, Cheng A, Sim F, Bray B, Patel A
J Oral Maxillofac Surg 2020 Oct;78(10):1869.e1-1869.e10. Epub 2020 Jun 29 doi: 10.1016/j.joms.2020.06.007. PMID: 32707040
Dotta JH, Miotto LN, Spin-Neto R, Ferrisse TM
Eur J Clin Invest 2020 Apr;50(4):e13214. Epub 2020 Mar 14 doi: 10.1111/eci.13214. PMID: 32048275
Kaffe I, Naor H, Buchner A
Dentomaxillofac Radiol 1997 Sep;26(5):299-303. doi: 10.1038/sj.dmfr.4600261. PMID: 9482003

Recent systematic reviews

Dotta JH, Miotto LN, Spin-Neto R, Ferrisse TM
Eur J Clin Invest 2020 Apr;50(4):e13214. Epub 2020 Mar 14 doi: 10.1111/eci.13214. PMID: 32048275
Saalim M, Sansare K, Karjodkar FR, Farman AG, Goyal SN, Sharma SR
Br J Oral Maxillofac Surg 2019 Dec;57(10):985-991. Epub 2019 Sep 21 doi: 10.1016/j.bjoms.2019.09.005. PMID: 31551163
Kauke M, Safi AF, Kreppel M, Grandoch A, Nickenig HJ, Zöller JE, Dreiseidler T
Dentomaxillofac Radiol 2018 Feb;47(2):20170262. Epub 2017 Nov 6 doi: 10.1259/dmfr.20170262. PMID: 29082773Free PMC Article

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