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Bipolar and Related Disorders

MedGen UID:
875788
•Concept ID:
C4042924
•
Mental or Behavioral Dysfunction

Definition

These disorders are related to both SCHIZOPHRENIA SPECTRUM AND OTHER PSYCHOTIC DISORDERS and DEPRESSIVE DISORDER in terms of symptomatology, family history, and genetics. (DSM-5). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBipolar and Related Disorders

Professional guidelines

PubMed

Brain stimulation treatment for bipolar disorder.
Mutz J
Bipolar Disord 2023 Feb;25(1):9-24. Epub 2022 Dec 21 doi: 10.1111/bdi.13283. PMID: 36515461Free PMC Article
Care Management for Serious Mental Illness: A Systematic Review and Meta-Analysis.
Lim CT, Caan MP, Kim CH, Chow CM, Leff HS, Tepper MC
Psychiatr Serv 2022 Feb 1;73(2):180-187. Epub 2021 Jul 13 doi: 10.1176/appi.ps.202000473. PMID: 34253036
New Insights Into Major Depression and the Treatment of Bipolar Depression.
Kalin NH
Am J Psychiatry 2021 Dec;178(12):1071-1074. doi: 10.1176/appi.ajp.2021.21101042. PMID: 34855453

Recent clinical studies

Therapy

Risk of Incident Psychosis and Mania With Prescription Amphetamines.
Moran LV, Skinner JP, Shinn AK, Nielsen K, Rao V, Taylor ST, Cohen TR, Erkol C, Merchant J, Mujica CA, Perlis RH, Ongur D
Am J Psychiatry 2024 Oct 1;181(10):901-909. Epub 2024 Sep 12 doi: 10.1176/appi.ajp.20230329. PMID: 39262211
Antidepressants and Bipolar Disorder: The Plot Thickens.
Gottlieb N, Young AH
Am J Psychiatry 2024 Jul 1;181(7):575-577. doi: 10.1176/appi.ajp.20240411. PMID: 38946275
Brain stimulation treatment for bipolar disorder.
Mutz J
Bipolar Disord 2023 Feb;25(1):9-24. Epub 2022 Dec 21 doi: 10.1111/bdi.13283. PMID: 36515461Free PMC Article
Technology and Mental Health: State of the Art for Assessment and Treatment.
Harvey PD, Depp CA, Rizzo AA, Strauss GP, Spelber D, Carpenter LL, Kalin NH, Krystal JH, McDonald WM, Nemeroff CB, Rodriguez CI, Widge AS, Torous J
Am J Psychiatry 2022 Dec 1;179(12):897-914. Epub 2022 Oct 6 doi: 10.1176/appi.ajp.21121254. PMID: 36200275
Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial.
Calabrese JR, Durgam S, Satlin A, Vanover KE, Davis RE, Chen R, Kozauer SG, Mates S, Sachs GS
Am J Psychiatry 2021 Dec;178(12):1098-1106. Epub 2021 Sep 23 doi: 10.1176/appi.ajp.2021.20091339. PMID: 34551584

Prognosis

Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.
Zwicker A, Fullerton JM, Mullins N, Rice F, Hafeman DM, van Haren NEM, Setiaman N, Merranko JA, Goldstein BI, Ferrera AG, Stapp EK, de la Serna E, Moreno D, Sugranyes G, Herrero SM, Roberts G, Toma C, Schofield PR, Edenberg HJ, Wilcox HC, McInnis MG, Powell V, Propper L, Denovan-Wright E, Rouleau G, Castro-Fornieles J, Hillegers MHJ, Birmaher B, Thapar A, Mitchell PB, Lewis CM, Alda M, Nurnberger JI, Uher R
Am J Psychiatry 2023 Apr 1;180(4):285-293. Epub 2023 Feb 22 doi: 10.1176/appi.ajp.20220476. PMID: 36856707
Paediatric bipolar disorder and its controversy.
Connors MH
Acta Neuropsychiatr 2023 Apr;35(2):96-103. Epub 2022 Nov 14 doi: 10.1017/neu.2022.28. PMID: 36373500
Individual characteristics of adolescent psychiatric patients accessing psychotherapy in China.
Ma J, Zhou H, Li X, Fu Q, Lu G
Sci Rep 2022 Oct 9;12(1):16943. doi: 10.1038/s41598-022-21320-2. PMID: 36210367Free PMC Article
Mental Health Costs of Inflammatory Bowel Diseases.
Szigethy E, Murphy SM, Ehrlich OG, Engel-Nitz NM, Heller CA, Henrichsen K, Lawton R, Meadows P, Allen JI
Inflamm Bowel Dis 2021 Jan 1;27(1):40-48. doi: 10.1093/ibd/izaa030. PMID: 32095835
Mixed features in major depressive disorder: diagnoses and treatments.
Suppes T, Ostacher M
CNS Spectr 2017 Apr;22(2):155-160. doi: 10.1017/S1092852917000256. PMID: 28462772

Clinical prediction guides

Risk of Incident Psychosis and Mania With Prescription Amphetamines.
Moran LV, Skinner JP, Shinn AK, Nielsen K, Rao V, Taylor ST, Cohen TR, Erkol C, Merchant J, Mujica CA, Perlis RH, Ongur D
Am J Psychiatry 2024 Oct 1;181(10):901-909. Epub 2024 Sep 12 doi: 10.1176/appi.ajp.20230329. PMID: 39262211
Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.
Zwicker A, Fullerton JM, Mullins N, Rice F, Hafeman DM, van Haren NEM, Setiaman N, Merranko JA, Goldstein BI, Ferrera AG, Stapp EK, de la Serna E, Moreno D, Sugranyes G, Herrero SM, Roberts G, Toma C, Schofield PR, Edenberg HJ, Wilcox HC, McInnis MG, Powell V, Propper L, Denovan-Wright E, Rouleau G, Castro-Fornieles J, Hillegers MHJ, Birmaher B, Thapar A, Mitchell PB, Lewis CM, Alda M, Nurnberger JI, Uher R
Am J Psychiatry 2023 Apr 1;180(4):285-293. Epub 2023 Feb 22 doi: 10.1176/appi.ajp.20220476. PMID: 36856707
Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial.
Calabrese JR, Durgam S, Satlin A, Vanover KE, Davis RE, Chen R, Kozauer SG, Mates S, Sachs GS
Am J Psychiatry 2021 Dec;178(12):1098-1106. Epub 2021 Sep 23 doi: 10.1176/appi.ajp.2021.20091339. PMID: 34551584
Olfactory Functioning in First-Episode Psychosis.
Kamath V, Lasutschinkow P, Ishizuka K, Sawa A
Schizophr Bull 2018 Apr 6;44(3):672-680. doi: 10.1093/schbul/sbx107. PMID: 28981913Free PMC Article
Mixed features in major depressive disorder: diagnoses and treatments.
Suppes T, Ostacher M
CNS Spectr 2017 Apr;22(2):155-160. doi: 10.1017/S1092852917000256. PMID: 28462772

Recent systematic reviews

Capacity to Consent in Healthcare: A Systematic Review and Meta-Analysis Comparing Patients with Bipolar Disorders and Schizophrenia Spectrum Disorders.
Morena D, Lippi M, Di Fazio N, Delogu G, Rinaldi R, Frati P, Fineschi V
Medicina (Kaunas) 2024 May 5;60(5) doi: 10.3390/medicina60050764. PMID: 38792947Free PMC Article
The resting metabolic rate of people with severe mental illness: a systematic review and meta-analysis.
Nian SY, Hirani V, Ardill-Young O, Ward PB, Curtis J, Teasdale SB
Br J Nutr 2023 Dec 28;130(12):2025-2038. Epub 2023 May 9 doi: 10.1017/S0007114523001162. PMID: 37157830
Care Management for Serious Mental Illness: A Systematic Review and Meta-Analysis.
Lim CT, Caan MP, Kim CH, Chow CM, Leff HS, Tepper MC
Psychiatr Serv 2022 Feb 1;73(2):180-187. Epub 2021 Jul 13 doi: 10.1176/appi.ps.202000473. PMID: 34253036
Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World: Systematic Review and Meta-Analysis of 47 Observational Studies.
Solmi M, Fiedorowicz J, Poddighe L, Delogu M, Miola A, Høye A, Heiberg IH, Stubbs B, Smith L, Larsson H, Attar R, Nielsen RE, Cortese S, Shin JI, Fusar-Poli P, Firth J, Yatham LN, Carvalho AF, Castle DJ, Seeman MV, Correll CU
Am J Psychiatry 2021 Sep 1;178(9):793-803. Epub 2021 Jul 14 doi: 10.1176/appi.ajp.2021.21010031. PMID: 34256605
Obstructive sleep apnea and psychiatric disorders: a systematic review.
Gupta MA, Simpson FC
J Clin Sleep Med 2015 Jan 15;11(2):165-75. doi: 10.5664/jcsm.4466. PMID: 25406268Free PMC Article

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