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Abnormality morphology of the macular vasculature

MedGen UID:
892754
•Concept ID:
C4072983
•
Anatomical Abnormality
Synonym: Abnormality of macular vasculature
 
HPO: HP:0030495

Definition

Any structural anomaly of the blood vessels of the macula. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality morphology of the macular vasculature

Professional guidelines

PubMed

Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article
Polypoidal choroidal vasculopathy: Pearls in diagnosis and management.
Anantharaman G, Sheth J, Bhende M, Narayanan R, Natarajan S, Rajendran A, Manayath G, Sen P, Biswas R, Banker A, Gupta C
Indian J Ophthalmol 2018 Jul;66(7):896-908. doi: 10.4103/ijo.IJO_1136_17. PMID: 29941728Free PMC Article
Polypoidal choroidal vasculopathy: angiographic characterization of the network vascular elements and a new treatment paradigm.
Costa RA, Navajas EV, Farah ME, Calucci D, Cardillo JA, Scott IU
Prog Retin Eye Res 2005 Sep;24(5):560-86. Epub 2005 Apr 18 doi: 10.1016/j.preteyeres.2005.01.001. PMID: 16005406

Recent clinical studies

Etiology

Ophthalmic characteristics and retinal vasculature changes in Williams syndrome, and its association with systemic diseases.
Yeh TC, Cheng HC, Li HY, Chi SC, Yang HY, Yu JY, Niu DM, Wang AG
Eye (Lond) 2023 Aug;37(11):2265-2271. Epub 2022 Nov 28 doi: 10.1038/s41433-022-02328-4. PMID: 36437422Free PMC Article
Assessment of the optic nerve, macular, and retinal vascular effects of COVID-19.
Ugurlu A, Agcayazi SB, Icel E, Budakoglu O, Unver E, Barkay O, Karakeçili F, Bayrakceken K
Can J Ophthalmol 2023 Dec;58(6):570-576. Epub 2022 Jun 30 doi: 10.1016/j.jcjo.2022.06.016. PMID: 35868440Free PMC Article
Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration.
Bharti K, den Hollander AI, Lakkaraju A, Sinha D, Williams DS, Finnemann SC, Bowes-Rickman C, Malek G, D'Amore PA
Exp Eye Res 2022 Sep;222:109170. Epub 2022 Jul 11 doi: 10.1016/j.exer.2022.109170. PMID: 35835183Free PMC Article
Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Polypoidal choroidal vasculopathy.
Ciardella AP, Donsoff IM, Huang SJ, Costa DL, Yannuzzi LA
Surv Ophthalmol 2004 Jan-Feb;49(1):25-37. doi: 10.1016/j.survophthal.2003.10.007. PMID: 14711438

Diagnosis

Assessment of the optic nerve, macular, and retinal vascular effects of COVID-19.
Ugurlu A, Agcayazi SB, Icel E, Budakoglu O, Unver E, Barkay O, Karakeçili F, Bayrakceken K
Can J Ophthalmol 2023 Dec;58(6):570-576. Epub 2022 Jun 30 doi: 10.1016/j.jcjo.2022.06.016. PMID: 35868440Free PMC Article
An Update on the Hemodynamic Model of Age-Related Macular Degeneration.
Rosenfeld PJ, Trivizki O, Gregori G, Wang RK
Am J Ophthalmol 2022 Mar;235:291-299. Epub 2021 Sep 9 doi: 10.1016/j.ajo.2021.08.015. PMID: 34509436
Optical coherence tomography angiography in diabetes: A review.
Battista M, Borrelli E, Sacconi R, Bandello F, Querques G
Eur J Ophthalmol 2020 May;30(3):411-416. Epub 2020 Jan 12 doi: 10.1177/1120672119899901. PMID: 31928211
Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article
Choroidal biomarkers.
Pichi F, Aggarwal K, Neri P, Salvetti P, Lembo A, Nucci P, Gemmy Cheung CM, Gupta V
Indian J Ophthalmol 2018 Dec;66(12):1716-1726. doi: 10.4103/ijo.IJO_893_18. PMID: 30451172Free PMC Article

Therapy

Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article
Gene transfer for ocular neovascularization and macular edema.
Campochiaro PA
Gene Ther 2012 Feb;19(2):121-6. Epub 2011 Nov 10 doi: 10.1038/gt.2011.164. PMID: 22071973
Therapeutic anti-VEGF antibodies.
Lien S, Lowman HB
Handb Exp Pharmacol 2008;(181):131-50. doi: 10.1007/978-3-540-73259-4_6. PMID: 18071944
Ultrastructure and organization of the cutaneous microvasculature in normal and pathologic states.
Braverman IM
J Invest Dermatol 1989 Aug;93(2 Suppl):2S-9S. doi: 10.1111/1523-1747.ep12580893. PMID: 2666519

Prognosis

THE RAP STUDY, REPORT 5: REDISCOVERING MACULAR NEOVASCULARIZATION TYPE 3: Multimodal Imaging of Fellow Eyes over 24 months.
Haj Najeeb B, Deak GG, Mylonas G, Sacu S, Gerendas BS, Schmidt-Erfurth U
Retina 2022 Mar 1;42(3):485-493. doi: 10.1097/IAE.0000000000003330. PMID: 35188490Free PMC Article
Foveal structure and visual function in nanophthalmos and posterior microphthalmos.
Müller PL, Treis T, Alsaedi A, Webster AR, Khaw P, Michaelides M, Wickham L, Siriwardena D, Foster P, Moosajee M, Pavesio C, Tufail A, Egan C
Br J Ophthalmol 2022 Aug;106(8):1164-1170. Epub 2021 Jul 22 doi: 10.1136/bjophthalmol-2020-318717. PMID: 34301612
INTERVORTEX VENOUS ANASTOMOSIS IN Pachychoroid-RELATED DISORDERS.
Spaide RF, Ledesma-Gil G, Gemmy Cheung CM
Retina 2021 May 1;41(5):997-1004. doi: 10.1097/IAE.0000000000003004. PMID: 33109938
Polypoidal choroidal vasculopathy: Pearls in diagnosis and management.
Anantharaman G, Sheth J, Bhende M, Narayanan R, Natarajan S, Rajendran A, Manayath G, Sen P, Biswas R, Banker A, Gupta C
Indian J Ophthalmol 2018 Jul;66(7):896-908. doi: 10.4103/ijo.IJO_1136_17. PMID: 29941728Free PMC Article
Polypoidal choroidal vasculopathy.
Ciardella AP, Donsoff IM, Huang SJ, Costa DL, Yannuzzi LA
Surv Ophthalmol 2004 Jan-Feb;49(1):25-37. doi: 10.1016/j.survophthal.2003.10.007. PMID: 14711438

Clinical prediction guides

Assessment of the optic nerve, macular, and retinal vascular effects of COVID-19.
Ugurlu A, Agcayazi SB, Icel E, Budakoglu O, Unver E, Barkay O, Karakeçili F, Bayrakceken K
Can J Ophthalmol 2023 Dec;58(6):570-576. Epub 2022 Jun 30 doi: 10.1016/j.jcjo.2022.06.016. PMID: 35868440Free PMC Article
Sildenafil in ophthalmology: An update.
Arora S, Surakiatchanukul T, Arora T, Cagini C, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Mar-Apr;67(2):463-487. Epub 2021 Jun 25 doi: 10.1016/j.survophthal.2021.06.004. PMID: 34175342
Optical coherence tomography angiography in diabetes: A review.
Battista M, Borrelli E, Sacconi R, Bandello F, Querques G
Eur J Ophthalmol 2020 May;30(3):411-416. Epub 2020 Jan 12 doi: 10.1177/1120672119899901. PMID: 31928211
Development and pathology of the hyaloid, choroidal and retinal vasculature.
Saint-Geniez M, D'Amore PA
Int J Dev Biol 2004;48(8-9):1045-58. doi: 10.1387/ijdb.041895ms. PMID: 15558494
Mechanisms of maculopathy.
Eagle RC Jr
Ophthalmology 1984 Jun;91(6):613-25. doi: 10.1016/s0161-6420(84)34259-2. PMID: 6205340

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