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Abnormal tubulointerstitial morphology

MedGen UID:
892966
Concept ID:
C4025732
Anatomical Abnormality
Synonym: Tubulointerstitial abnormalities
 
HPO: HP:0001969

Definition

An abnormality that involves the tubules and interstitial tissue of the kidney. [from HPO]

Conditions with this feature

Nephropathy, progressive tubulointerstitial, with cholestatic liver disease
MedGen UID:
355562
Concept ID:
C1865831
Disease or Syndrome

Professional guidelines

PubMed

Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:255-261. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.041. PMID: 33845023Free PMC Article
Wang GQ, Rui HL, Dong HR, Sun LJ, Yang M, Wang YY, Ye N, Zhao ZR, Liu XJ, Xu XY, Chen YP, Cheng H
Sci Rep 2020 May 25;10(1):8616. doi: 10.1038/s41598-020-65491-2. PMID: 32451462Free PMC Article
Kawano M, Saeki T, Nakashima H, Nishi S, Yamaguchi Y, Hisano S, Yamanaka N, Inoue D, Yamamoto M, Takahashi H, Nomura H, Taguchi T, Umehara H, Makino H, Saito T
Clin Exp Nephrol 2011 Oct;15(5):615-626. Epub 2011 Sep 7 doi: 10.1007/s10157-011-0521-2. PMID: 21898030

Recent clinical studies

Etiology

Petzold F, Billot K, Chen X, Henry C, Filhol E, Martin Y, Avramescu M, Douillet M, Morinière V, Krug P, Jeanpierre C, Tory K, Boyer O, Burgun A, Servais A, Salomon R, Benmerah A, Heidet L, Garcelon N, Antignac C, Zaidan M, Saunier S; INSERM–Necker Hospital NPH collaborative group
Kidney Int 2023 Aug;104(2):378-387. Epub 2023 May 23 doi: 10.1016/j.kint.2023.05.007. PMID: 37230223
Lemoine H, Raud L, Foulquier F, Sayer JA, Lambert B, Olinger E, Lefèvre S, Knebelmann B, Harris PC, Trouvé P, Desprès A, Duneau G, Matignon M, Poyet A, Jourde-Chiche N, Guerrot D, Lemoine S, Seret G, Barroso-Gil M, Bingham C, Gilbert R; Genomics England Research Consortium; Genkyst Study Group, Le Meur Y, Audrézet MP, Cornec-Le Gall E
Am J Hum Genet 2022 Aug 4;109(8):1484-1499. Epub 2022 Jul 26 doi: 10.1016/j.ajhg.2022.06.013. PMID: 35896117Free PMC Article
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:255-261. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.041. PMID: 33845023Free PMC Article
Fioretto P, Mauer M
Semin Nephrol 2007 Mar;27(2):195-207. doi: 10.1016/j.semnephrol.2007.01.012. PMID: 17418688Free PMC Article
Bernstein J
Pediatr Nephrol 1993 Aug;7(4):464-70. doi: 10.1007/BF00857576. PMID: 8398663

Diagnosis

Cao JL, Srivastava SK, Venkat A, Lowder CY, Sharma S
Ophthalmol Retina 2020 Feb;4(2):189-197. Epub 2019 Sep 20 doi: 10.1016/j.oret.2019.08.012. PMID: 31708486
Armstrong ME, Thomas CP
Curr Opin Nephrol Hypertens 2019 Mar;28(2):183-194. doi: 10.1097/MNH.0000000000000486. PMID: 30601180
Kamath N, Iyengar A
Pediatr Nephrol 2018 Aug;33(8):1317-1326. Epub 2017 Sep 6 doi: 10.1007/s00467-017-3785-2. PMID: 28879600
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Vehaskari VM
Adv Chronic Kidney Dis 2011 Sep;18(5):317-23. doi: 10.1053/j.ackd.2011.07.001. PMID: 21896372

Therapy

Zee J, Liu Q, Smith AR, Hodgin JB, Rosenberg A, Gillespie BW, Holzman LB, Barisoni L, Mariani LH; Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members
J Am Soc Nephrol 2022 Jul;33(7):1411-1426. Epub 2022 May 17 doi: 10.1681/ASN.2021101396. PMID: 35581011Free PMC Article
Lu Z, Zhong Y, Liu W, Xiang L, Deng Y
J Diabetes Res 2019;2019:2697672. Epub 2019 Aug 25 doi: 10.1155/2019/2697672. PMID: 31534972Free PMC Article
Kamath N, Iyengar A
Pediatr Nephrol 2018 Aug;33(8):1317-1326. Epub 2017 Sep 6 doi: 10.1007/s00467-017-3785-2. PMID: 28879600
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Nishi S, Imai N, Yoshida K, Ito Y, Saeki T
Clin Exp Nephrol 2011 Dec;15(6):810-9. Epub 2011 Aug 26 doi: 10.1007/s10157-011-0526-x. PMID: 21870078

Prognosis

Zee J, Liu Q, Smith AR, Hodgin JB, Rosenberg A, Gillespie BW, Holzman LB, Barisoni L, Mariani LH; Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members
J Am Soc Nephrol 2022 Jul;33(7):1411-1426. Epub 2022 May 17 doi: 10.1681/ASN.2021101396. PMID: 35581011Free PMC Article
Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Vehaskari VM
Adv Chronic Kidney Dis 2011 Sep;18(5):317-23. doi: 10.1053/j.ackd.2011.07.001. PMID: 21896372
Remuzzi G, Zoja C, Bertani T
Curr Opin Nephrol Hypertens 1993 May;2(3):465-74. doi: 10.1097/00041552-199305000-00015. PMID: 7922207

Clinical prediction guides

Zee J, Liu Q, Smith AR, Hodgin JB, Rosenberg A, Gillespie BW, Holzman LB, Barisoni L, Mariani LH; Nephrotic Syndrome Study Network (NEPTUNE); NEPTUNE Members
J Am Soc Nephrol 2022 Jul;33(7):1411-1426. Epub 2022 May 17 doi: 10.1681/ASN.2021101396. PMID: 35581011Free PMC Article
Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Salomon R, Saunier S, Niaudet P
Pediatr Nephrol 2009 Dec;24(12):2333-44. Epub 2008 Jul 8 doi: 10.1007/s00467-008-0840-z. PMID: 18607645Free PMC Article
Remuzzi G, Zoja C, Bertani T
Curr Opin Nephrol Hypertens 1993 May;2(3):465-74. doi: 10.1097/00041552-199305000-00015. PMID: 7922207

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