U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mild squamous cell atypia

MedGen UID:
90721
•Concept ID:
C0333870
•
Cell or Molecular Dysfunction
Synonym: Mild Squamous Cell Atypia
SNOMED CT: Mild squamous cell atypia (23108001)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMild squamous cell atypia

Professional guidelines

PubMed

Uterine Tumors Resembling Ovarian Sex Cord Tumors: A Clinicopathologic Study of 75 Cases Emphasizing Features Predicting Adverse Outcome and Differential Diagnosis.
Boyraz B, Watkins JC, Young RH, Oliva E
Am J Surg Pathol 2023 Feb 1;47(2):234-247. Epub 2022 Oct 27 doi: 10.1097/PAS.0000000000001981. PMID: 36306239
Evaluation of diagnostic criteria of actinic keratosis through reflectance confocal microscopy.
Nascimento Cavalleiro Macedo Mota A, Piñeiro-Maceira JM, Baptista Barcaui C
Skin Res Technol 2020 Nov;26(6):883-890. Epub 2020 Jun 25 doi: 10.1111/srt.12890. PMID: 32585761
Loss of primary cilia correlates with cytologic severity in dysplastic melanocytic nevi.
Lang UE, Cheung C, Vladar EK, Swetter SM, Kim J
J Cutan Pathol 2016 Feb;43(2):113-9. Epub 2015 Sep 11 doi: 10.1111/cup.12612. PMID: 26272818

Recent clinical studies

Etiology

Atypical Endometriosis: Comprehensive Characterization of Clinicopathologic, Immunohistochemical, and Molecular Features.
Wepy C, Nucci MR, Parra-Herran C
Int J Gynecol Pathol 2024 Jan 1;43(1):70-77. Epub 2023 Mar 13 doi: 10.1097/PGP.0000000000000952. PMID: 37043650
Abnormal p53 Immunohistochemical Patterns Shed Light on the Aggressiveness of Oral Epithelial Dysplasia.
Novack R, Zhang L, Hoang LN, Kadhim M, Ng TL, Poh CF, Kevin Ko YC
Mod Pathol 2023 Jul;36(7):100153. Epub 2023 Mar 9 doi: 10.1016/j.modpat.2023.100153. PMID: 36906072
The significance of Melan-A-positive pagetoid melanocytosis in dysplastic nevi.
Huwait H, Hijazi N, Martinka M, Crawford RI
Am J Dermatopathol 2014 Apr;36(4):340-3. doi: 10.1097/DAD.0b013e3182a7aa7c. PMID: 24736669
Cytology of nipple discharge in florid gynecomastia.
Kapila K, Verma K
Acta Cytol 2003 Jan-Feb;47(1):36-40. doi: 10.1159/000326472. PMID: 12585028
Epithelial cell kinetics in oral leukoplakia.
Warnakulasuriya KA, MacDonald DG
J Oral Pathol Med 1995 Apr;24(4):165-9. doi: 10.1111/j.1600-0714.1995.tb01159.x. PMID: 7783005

Diagnosis

Atypical Endometriosis: Comprehensive Characterization of Clinicopathologic, Immunohistochemical, and Molecular Features.
Wepy C, Nucci MR, Parra-Herran C
Int J Gynecol Pathol 2024 Jan 1;43(1):70-77. Epub 2023 Mar 13 doi: 10.1097/PGP.0000000000000952. PMID: 37043650
Abnormal p53 Immunohistochemical Patterns Shed Light on the Aggressiveness of Oral Epithelial Dysplasia.
Novack R, Zhang L, Hoang LN, Kadhim M, Ng TL, Poh CF, Kevin Ko YC
Mod Pathol 2023 Jul;36(7):100153. Epub 2023 Mar 9 doi: 10.1016/j.modpat.2023.100153. PMID: 36906072
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
The significance of Melan-A-positive pagetoid melanocytosis in dysplastic nevi.
Huwait H, Hijazi N, Martinka M, Crawford RI
Am J Dermatopathol 2014 Apr;36(4):340-3. doi: 10.1097/DAD.0b013e3182a7aa7c. PMID: 24736669
Ruptured appendiceal diverticula mimicking low-grade appendiceal mucinous neoplasms.
Hsu M, Young RH, Misdraji J
Am J Surg Pathol 2009 Oct;33(10):1515-21. doi: 10.1097/PAS.0b013e3181abe31b. PMID: 19623035

Therapy

Fine-needle aspiration biopsy of endometriosis of the abdominal wall: a potential diagnostic pitfall.
Aziz Z, Wang D
Diagn Cytopathol 2011 Jun;39(6):443-5. Epub 2010 Aug 20 doi: 10.1002/dc.21458. PMID: 20730899
Shammah-induced oral leukoplakia-like lesions.
Zhang X, Schmitz W, Gelderblom HR, Reichart PA
Oral Oncol 2001 Oct;37(7):609-12. doi: 10.1016/s1368-8375(00)00123-8. PMID: 11564584
Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis.
Franklin WA, Gazdar AF, Haney J, Wistuba II, La Rosa FG, Kennedy T, Ritchey DM, Miller YE
J Clin Invest 1997 Oct 15;100(8):2133-7. doi: 10.1172/JCI119748. PMID: 9329980Free PMC Article
Painless orbital apex syndrome from mucormycosis.
Balch K, Phillips PH, Newman NJ
J Neuroophthalmol 1997 Sep;17(3):178-82. PMID: 9304530
Histologic changes in the breast after fine-needle aspiration.
Lee KC, Chan JK, Ho LC
Am J Surg Pathol 1994 Oct;18(10):1039-47. doi: 10.1097/00000478-199410000-00007. PMID: 8092395

Prognosis

Abnormal p53 Immunohistochemical Patterns Shed Light on the Aggressiveness of Oral Epithelial Dysplasia.
Novack R, Zhang L, Hoang LN, Kadhim M, Ng TL, Poh CF, Kevin Ko YC
Mod Pathol 2023 Jul;36(7):100153. Epub 2023 Mar 9 doi: 10.1016/j.modpat.2023.100153. PMID: 36906072
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Exfoliation of Alveolar Rhabdomyosarcoma Cells in the Ascites of a 50-Year-Old Woman: Diagnostic Challenges and Literature Review.
Motoda N, Nakamura Y, Kuroki M, Yoneyama K, Isshiki S, Ohashi R, Naito Z
J Nippon Med Sch 2019 Sep 3;86(4):236-241. Epub 2019 Apr 26 doi: 10.1272/jnms.JNMS.2018_86-404. PMID: 31061253
Cytology of nipple discharge in florid gynecomastia.
Kapila K, Verma K
Acta Cytol 2003 Jan-Feb;47(1):36-40. doi: 10.1159/000326472. PMID: 12585028
Epithelial cell kinetics in oral leukoplakia.
Warnakulasuriya KA, MacDonald DG
J Oral Pathol Med 1995 Apr;24(4):165-9. doi: 10.1111/j.1600-0714.1995.tb01159.x. PMID: 7783005

Clinical prediction guides

NRAS(Q61R)-driven atypical melanocytic tumor with blue nevus-like morphology: A case report.
Hiraki T, Mori H, Misawa J, Yunoki M, Goto K
J Cutan Pathol 2024 Dec;51(12):948-953. Epub 2024 Aug 23 doi: 10.1111/cup.14709. PMID: 39177027
Abnormal p53 Immunohistochemical Patterns Shed Light on the Aggressiveness of Oral Epithelial Dysplasia.
Novack R, Zhang L, Hoang LN, Kadhim M, Ng TL, Poh CF, Kevin Ko YC
Mod Pathol 2023 Jul;36(7):100153. Epub 2023 Mar 9 doi: 10.1016/j.modpat.2023.100153. PMID: 36906072
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Novel genetic characteristics of multifocal micronodular pneumocyte hyperplasia (MMPH): a case report with frequent BRAF mutations analyzed by next-generation sequencing supporting benign behaviors of MMPH.
Inoue C, Saito R, Kishikawa S, Hayashi T, Kumasaka T, Yamada T, Oishi H, Yamazaki Y, Fujishima F, Watanabe M, Sasano H
Virchows Arch 2021 Sep;479(3):637-641. Epub 2021 Jan 14 doi: 10.1007/s00428-020-03013-1. PMID: 33443622
Epithelial cell kinetics in oral leukoplakia.
Warnakulasuriya KA, MacDonald DG
J Oral Pathol Med 1995 Apr;24(4):165-9. doi: 10.1111/j.1600-0714.1995.tb01159.x. PMID: 7783005

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...