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Severe columnar cell atypia

MedGen UID:
90724
•Concept ID:
C0333879
•
Cell or Molecular Dysfunction
Synonym: Severe Columnar Cell Atypia
SNOMED CT: Severe columnar cell atypia (28218003)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSevere columnar cell atypia

Professional guidelines

PubMed

Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept!
Moinfar F
Arch Pathol Lab Med 2009 Jun;133(6):879-92. doi: 10.5858/133.6.879. PMID: 19492880
Endocervical columnar cell intraepithelial neoplasia. II. Grades of expression of cytomorphologic criteria.
van Aspert-van Erp AJ, van 't Hof-Grootenboer AB, Brugal G, Vooijs GP
Acta Cytol 1995 Nov-Dec;39(6):1216-32. PMID: 7483999
Endocervical columnar cell intraepithelial neoplasia. I. Discriminating cytomorphologic criteria.
van Aspert-van Erp AJ, van 't Hof-Grootenboer AB, Brugal G, Vooijs GP
Acta Cytol 1995 Nov-Dec;39(6):1199-215. PMID: 7483998

Recent clinical studies

Etiology

High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Flat epithelial atypia of the breast: pathological-radiological correlation.
Solorzano S, Mesurolle B, Omeroglu A, El Khoury M, Kao E, Aldis A, Meterissian S
AJR Am J Roentgenol 2011 Sep;197(3):740-6. doi: 10.2214/AJR.10.5265. PMID: 21862819
Immunohistochemical and morphologic findings in columnar cell lesions of the breast.
Demiralay E, Demirhan B, Kocbiyik A, Sar A, Altaca GL
Indian J Pathol Microbiol 2011 Apr-Jun;54(2):335-8. doi: 10.4103/0377-4929.81630. PMID: 21623085
Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma.
Sandison A
Head Neck Pathol 2009 Sep;3(3):260-2. Epub 2009 Aug 20 doi: 10.1007/s12105-009-0136-z. PMID: 20596982Free PMC Article
In situ detection of nuclear atypia in Barrett's esophagus by using angle-resolved low-coherence interferometry.
Pyhtila JW, Chalut KJ, Boyer JD, Keener J, D'Amico T, Gottfried M, Gress F, Wax A
Gastrointest Endosc 2007 Mar;65(3):487-91. doi: 10.1016/j.gie.2006.10.016. PMID: 17321252

Diagnosis

High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Flat epithelial atypia of the breast: pathological-radiological correlation.
Solorzano S, Mesurolle B, Omeroglu A, El Khoury M, Kao E, Aldis A, Meterissian S
AJR Am J Roentgenol 2011 Sep;197(3):740-6. doi: 10.2214/AJR.10.5265. PMID: 21862819
Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma.
Sandison A
Head Neck Pathol 2009 Sep;3(3):260-2. Epub 2009 Aug 20 doi: 10.1007/s12105-009-0136-z. PMID: 20596982Free PMC Article
Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept!
Moinfar F
Arch Pathol Lab Med 2009 Jun;133(6):879-92. doi: 10.5858/133.6.879. PMID: 19492880
Cytologic diagnosis of columnar-cell lesions of the breast.
Jensen KC, Kong CS
Diagn Cytopathol 2007 Feb;35(2):73-9. doi: 10.1002/dc.20601. PMID: 17230565

Therapy

Cytopathologic changes associated with intrauterine contraceptive devices. A review of cervico-vaginal smears in 350 women.
Pillay B, Gregory AR, Subbiah M
Med J Malaysia 1994 Mar;49(1):74-7. PMID: 8057995

Prognosis

Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma.
Sandison A
Head Neck Pathol 2009 Sep;3(3):260-2. Epub 2009 Aug 20 doi: 10.1007/s12105-009-0136-z. PMID: 20596982Free PMC Article
Benign and malignant papillary lesions of the breast. A cytomorphologic study.
Jeffrey PB, Ljung BM
Am J Clin Pathol 1994 Apr;101(4):500-7. doi: 10.1093/ajcp/101.4.500. PMID: 8160644
Localizing chlamydial infection in cervical biopsies with the immunoperoxidase technique.
Crum CP, Mitao M, Winkler B, Reumann W, Boon ME, Richart RM
Int J Gynecol Pathol 1984;3(2):191-7. doi: 10.1097/00004347-198402000-00007. PMID: 6386718
Endocervical columnar cell atypia coincident with cervical neoplasia characterized by digital image analysis.
Rosenthal DL, McLatchie C, Stern E, White BS, Castleman KR
Acta Cytol 1982 Mar-Apr;26(2):115-20. PMID: 7044016
Sputum cytology of asbestosis patients.
Huuskonen MS, Taskinen E, Vaaranen V
Scand J Work Environ Health 1978 Dec;4(4):284-94. doi: 10.5271/sjweh.2697. PMID: 734389

Clinical prediction guides

High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate.
Zhou M
Mod Pathol 2018 Jan;31(S1):S71-79. doi: 10.1038/modpathol.2017.138. PMID: 29297491
Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma.
Sandison A
Head Neck Pathol 2009 Sep;3(3):260-2. Epub 2009 Aug 20 doi: 10.1007/s12105-009-0136-z. PMID: 20596982Free PMC Article
Endocervical columnar cell intraepithelial neoplasia (ECCIN). 3. Interobserver variability in feature use.
van Aspert van Erp AJ, van't Hof Grootenboer AE, Brugal G, Vooijs GP
Anal Cell Pathol 1996 Mar;10(2):115-35. PMID: 8721954
Endocervical columnar cell intraepithelial neoplasia. II. Grades of expression of cytomorphologic criteria.
van Aspert-van Erp AJ, van 't Hof-Grootenboer AB, Brugal G, Vooijs GP
Acta Cytol 1995 Nov-Dec;39(6):1216-32. PMID: 7483999
Endocervical columnar cell atypia coincident with cervical neoplasia characterized by digital image analysis.
Rosenthal DL, McLatchie C, Stern E, White BS, Castleman KR
Acta Cytol 1982 Mar-Apr;26(2):115-20. PMID: 7044016

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