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Severe koilocytotic atypia

MedGen UID:
90730
•Concept ID:
C0333899
•
Cell or Molecular Dysfunction
Synonym: Severe Koilocytotic Atypia
SNOMED CT: Severe koilocytotic atypia (28126000)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSevere koilocytotic atypia

Recent clinical studies

Etiology

Human T-cell lymphotropic virus type I and severe neoplasia of the cervix in Jamaica.
Strickler HD, Rattray C, Escoffery C, Manns A, Schiffman MH, Brown C, Cranston B, Hanchard B, Palefsky JM, Blattner WA
Int J Cancer 1995 Mar 29;61(1):23-6. doi: 10.1002/ijc.2910610105. PMID: 7705929
Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: a randomized trial.
Meyskens FL Jr, Surwit E, Moon TE, Childers JM, Davis JR, Dorr RT, Johnson CS, Alberts DS
J Natl Cancer Inst 1994 Apr 6;86(7):539-43. doi: 10.1093/jnci/86.7.539. PMID: 8133537
Cytologic indicators of condylomatous lesions of the uterine cervix with histologic correlation: an outpatient laboratory's experience.
Selvaggi SM
Diagn Cytopathol 1988;4(4):277-82. doi: 10.1002/dc.2840040402. PMID: 3254805
Papillomavirus infection of the anogenital region: correlation between histology, clinical picture, and virus type. Proposal of a new nomenclature.
Gross G, Ikenberg H, Gissmann L, Hagedorn M
J Invest Dermatol 1985 Aug;85(2):147-52. doi: 10.1111/1523-1747.ep12276576. PMID: 2991390
Vulvar intraepithelial neoplasia (severe atypia and carcinoma in situ). A clinicopathologic analysis of 41 cases.
Crum CP, Liskow A, Petras P, Keng WC, Frick HC 2nd
Cancer 1984 Oct 1;54(7):1429-34. doi: 10.1002/1097-0142(19841001)54:7<1429::aid-cncr2820540733>3.0.co;2-g. PMID: 6088029

Diagnosis

Spontaneous evolution of human papillomavirus infection in the uterine cervix.
Paraskevaidis E, Kalantaridou SN, Georgiou I, Koliopoulos G, Pappa L, Malamou-Mitsi V, Agnantis NJ, Kitchener HC, Lolis DE
Anticancer Res 1999 Jul-Aug;19(4C):3473-8. PMID: 10629638
Vulvar vestibulitis. A histopathologic study of 36 cases, including human papillomavirus in situ hybridization analysis.
Prayson RA, Stoler MH, Hart WR
Am J Surg Pathol 1995 Feb;19(2):154-60. doi: 10.1097/00000478-199502000-00004. PMID: 7832275
Cytological analysis for human papillomavirus DNAs in cervical intraepithelial neoplasia by in situ hybridization.
Nagai N, Takehara K, Murakami T, Ohama K
Hiroshima J Med Sci 1994 Sep;43(3):105-10. PMID: 7896562
Vulvar intraepithelial neoplasia (severe atypia and carcinoma in situ). A clinicopathologic analysis of 41 cases.
Crum CP, Liskow A, Petras P, Keng WC, Frick HC 2nd
Cancer 1984 Oct 1;54(7):1429-34. doi: 10.1002/1097-0142(19841001)54:7<1429::aid-cncr2820540733>3.0.co;2-g. PMID: 6088029

Therapy

Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: a randomized trial.
Meyskens FL Jr, Surwit E, Moon TE, Childers JM, Davis JR, Dorr RT, Johnson CS, Alberts DS
J Natl Cancer Inst 1994 Apr 6;86(7):539-43. doi: 10.1093/jnci/86.7.539. PMID: 8133537

Prognosis

Spontaneous evolution of human papillomavirus infection in the uterine cervix.
Paraskevaidis E, Kalantaridou SN, Georgiou I, Koliopoulos G, Pappa L, Malamou-Mitsi V, Agnantis NJ, Kitchener HC, Lolis DE
Anticancer Res 1999 Jul-Aug;19(4C):3473-8. PMID: 10629638
Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: a randomized trial.
Meyskens FL Jr, Surwit E, Moon TE, Childers JM, Davis JR, Dorr RT, Johnson CS, Alberts DS
J Natl Cancer Inst 1994 Apr 6;86(7):539-43. doi: 10.1093/jnci/86.7.539. PMID: 8133537
Intraepithelial neoplasia of the anal canal in hemorrhoidal tissue: a study of 19 cases.
Foust RL, Dean PJ, Stoler MH, Moinuddin SM
Hum Pathol 1991 Jun;22(6):528-34. doi: 10.1016/0046-8177(91)90228-h. PMID: 1650751
Vulvar intraepithelial neoplasia (severe atypia and carcinoma in situ). A clinicopathologic analysis of 41 cases.
Crum CP, Liskow A, Petras P, Keng WC, Frick HC 2nd
Cancer 1984 Oct 1;54(7):1429-34. doi: 10.1002/1097-0142(19841001)54:7<1429::aid-cncr2820540733>3.0.co;2-g. PMID: 6088029

Clinical prediction guides

Spontaneous evolution of human papillomavirus infection in the uterine cervix.
Paraskevaidis E, Kalantaridou SN, Georgiou I, Koliopoulos G, Pappa L, Malamou-Mitsi V, Agnantis NJ, Kitchener HC, Lolis DE
Anticancer Res 1999 Jul-Aug;19(4C):3473-8. PMID: 10629638
Vulvar vestibulitis. A histopathologic study of 36 cases, including human papillomavirus in situ hybridization analysis.
Prayson RA, Stoler MH, Hart WR
Am J Surg Pathol 1995 Feb;19(2):154-60. doi: 10.1097/00000478-199502000-00004. PMID: 7832275
Intraepithelial neoplasia of the anal canal in hemorrhoidal tissue: a study of 19 cases.
Foust RL, Dean PJ, Stoler MH, Moinuddin SM
Hum Pathol 1991 Jun;22(6):528-34. doi: 10.1016/0046-8177(91)90228-h. PMID: 1650751

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