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Granulomatous angiitis

MedGen UID:
9088
•Concept ID:
C0018202
•
Disease or Syndrome
Synonyms: Angiitis, Granulomatous; Arteritis, Granulomatous; Granulomatous Angiitis; Granulomatous Arteritis
SNOMED CT: Granulomatous vasculitis (1260127003)
 
Monarch Initiative: MONDO:0002341

Definition

Inflammation of the arteries that is characterized by the presence of granulomas. [from NCI]

Professional guidelines

PubMed

Primary Angiitis of Central Nervous System-Tumor-Like Mass Lesions: Report of Six Biopsy Confirmed Cases.
Murthy JMK, Challa S, Parida S, Murthy TVRK, Basha Paspala SA
Neurol India 2021 Mar-Apr;69(2):451-456. doi: 10.4103/0028-3886.314536. PMID: 33904474

Recent clinical studies

Etiology

Adverse drug reactions of montelukast in children and adults.
Haarman MG, van Hunsel F, de Vries TW
Pharmacol Res Perspect 2017 Oct;5(5) doi: 10.1002/prp2.341. PMID: 28971612Free PMC Article
New concepts in lacunar stroke etiology: the constellation of small-vessel arterial disease.
Arboix A, Martí-Vilalta JL
Cerebrovasc Dis 2004;17 Suppl 1:58-62. doi: 10.1159/000074796. PMID: 14694281
The Churg Strauss syndrome (allergic granulomatous angiitis): review and update.
Abril A, Calamia KT, Cohen MD
Semin Arthritis Rheum 2003 Oct;33(2):106-14. doi: 10.1016/s0049-0172(03)00083-0. PMID: 14625818
Herpes simplex pancreatitis.
Shintaku M, Umehara Y, Iwaisako K, Tahara M, Adachi Y
Arch Pathol Lab Med 2003 Feb;127(2):231-4. doi: 10.5858/2003-127-231-HS. PMID: 12562243
Granulomatous angiitis of the CNS.
Sandhu R, Alexander WS, Hornabrook RW, Stehbens WE
Arch Neurol 1979 Jul;36(7):433-5. doi: 10.1001/archneur.1979.00500430063009. PMID: 36873

Diagnosis

Adult and childhood vasculitis.
Younger DS
Handb Clin Neurol 2023;195:653-705. doi: 10.1016/B978-0-323-98818-6.00008-X. PMID: 37562892
Granulomatous Angiitis: Twenty Years Later.
Younger DS
Neurol Clin 2019 May;37(2):267-277. doi: 10.1016/j.ncl.2019.01.011. PMID: 30952409
Primary Angiitis of the Central Nervous System.
Mandal J, Chung SA
Rheum Dis Clin North Am 2017 Nov;43(4):503-518. doi: 10.1016/j.rdc.2017.06.001. PMID: 29061238
Paraneoplastic neurological syndromes in Hodgkin and non-Hodgkin lymphomas.
Graus F, Ariño H, Dalmau J
Blood 2014 May 22;123(21):3230-8. Epub 2014 Apr 4 doi: 10.1182/blood-2014-03-537506. PMID: 24705493Free PMC Article
Cerebral vasculitis.
Adams HP Jr
Handb Clin Neurol 2014;119:475-94. doi: 10.1016/B978-0-7020-4086-3.00031-X. PMID: 24365314

Therapy

The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Di Salvo E, Patella V, Casciaro M, Gangemi S
Pulm Pharmacol Ther 2020 Feb;60:101875. Epub 2019 Dec 11 doi: 10.1016/j.pupt.2019.101875. PMID: 31837440
Granulomatous Angiitis of the Central Nervous System Associated with Hodgkin's Lymphoma: Case Report and Literature Review.
Lopez-Chiriboga AS, Yoon JW, Siegel JL, Harriott AM, Pirris S, Eidelman BH, Freeman WD
J Stroke Cerebrovasc Dis 2018 Jan;27(1):e5-e8. Epub 2017 Sep 21 doi: 10.1016/j.jstrokecerebrovasdis.2017.08.029. PMID: 28943218Free PMC Article
Primary Angiitis of the Central Nervous System.
Mandal J, Chung SA
Rheum Dis Clin North Am 2017 Nov;43(4):503-518. doi: 10.1016/j.rdc.2017.06.001. PMID: 29061238
Adverse drug reactions of montelukast in children and adults.
Haarman MG, van Hunsel F, de Vries TW
Pharmacol Res Perspect 2017 Oct;5(5) doi: 10.1002/prp2.341. PMID: 28971612Free PMC Article
Association of asthma therapy and Churg-Strauss syndrome: an analysis of postmarketing surveillance data.
DuMouchel W, Smith ET, Beasley R, Nelson H, Yang X, Fram D, Almenoff JS
Clin Ther 2004 Jul;26(7):1092-1104. doi: 10.1016/s0149-2918(04)90181-6. PMID: 15336474

Prognosis

The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Di Salvo E, Patella V, Casciaro M, Gangemi S
Pulm Pharmacol Ther 2020 Feb;60:101875. Epub 2019 Dec 11 doi: 10.1016/j.pupt.2019.101875. PMID: 31837440
ANCA-associated vasculitis: diagnostic and therapeutic strategy.
Ozaki S
Allergol Int 2007 Jun;56(2):87-96. Epub 2007 May 1 doi: 10.2332/allergolint.R-07-141. PMID: 17460438
New concepts in lacunar stroke etiology: the constellation of small-vessel arterial disease.
Arboix A, Martí-Vilalta JL
Cerebrovasc Dis 2004;17 Suppl 1:58-62. doi: 10.1159/000074796. PMID: 14694281
The Churg Strauss syndrome (allergic granulomatous angiitis): review and update.
Abril A, Calamia KT, Cohen MD
Semin Arthritis Rheum 2003 Oct;33(2):106-14. doi: 10.1016/s0049-0172(03)00083-0. PMID: 14625818
The neurologic presentation of vasculitic and rheumatologic syndromes. A review.
Sigal LH
Medicine (Baltimore) 1987 May;66(3):157-80. doi: 10.1097/00005792-198705000-00001. PMID: 3553845

Clinical prediction guides

Primary granulomatous angiitis of the CNS preferentially involving small veins with a granulomatous leukoencephalitis-like lesion in the cerebrum.
Okeda R, Ito K, Tsumura K, Eishi Y
Neuropathology 2013 Oct;33(5):547-52. Epub 2012 Dec 21 doi: 10.1111/neup.12006. PMID: 23279573
Head and neck manifestations of Wegener's granulomatosis.
Gottschlich S, Ambrosch P, Kramkowski D, Laudien M, Buchelt T, Gross WL, Hellmich B
Rhinology 2006 Dec;44(4):227-33. PMID: 17216737
Association of asthma therapy and Churg-Strauss syndrome: an analysis of postmarketing surveillance data.
DuMouchel W, Smith ET, Beasley R, Nelson H, Yang X, Fram D, Almenoff JS
Clin Ther 2004 Jul;26(7):1092-1104. doi: 10.1016/s0149-2918(04)90181-6. PMID: 15336474
Pulmonary vascular involvement in sarcoidosis: granulomatous angiitis and microangiopathy in transbronchial lung biopsies.
Takemura T, Matsui Y, Oritsu M, Akiyama O, Hiraga Y, Omichi M, Hirasawa M, Saiki S, Tamura S, Mochizuki I
Virchows Arch A Pathol Anat Histopathol 1991;418(4):361-8. doi: 10.1007/BF01600167. PMID: 1850897
Pleural effusions in Wegener's granulomatosis: report of five patients and a brief review of the literature.
Bambery P, Sakhuja V, Behera D, Deodhar SD
Scand J Rheumatol 1991;20(6):445-7. doi: 10.3109/03009749109096825. PMID: 1771403

Recent systematic reviews

The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Di Salvo E, Patella V, Casciaro M, Gangemi S
Pulm Pharmacol Ther 2020 Feb;60:101875. Epub 2019 Dec 11 doi: 10.1016/j.pupt.2019.101875. PMID: 31837440

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