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Granulomatous angiitis

MedGen UID:
9088
•Concept ID:
C0018202
•
Disease or Syndrome
Synonyms: Angiitis, Granulomatous; Arteritis, Granulomatous; Granulomatous Angiitis; Granulomatous Arteritis
SNOMED CT: Granulomatous vasculitis (1260127003)
 
Monarch Initiative: MONDO:0002341

Definition

Inflammation of the arteries that is characterized by the presence of granulomas. [from NCI]

Professional guidelines

PubMed

Primary Angiitis of Central Nervous System-Tumor-Like Mass Lesions: Report of Six Biopsy Confirmed Cases.
Murthy JMK, Challa S, Parida S, Murthy TVRK, Basha Paspala SA
Neurol India 2021 Mar-Apr;69(2):451-456. doi: 10.4103/0028-3886.314536. PMID: 33904474

Recent clinical studies

Etiology

Primary angiitis of the central nervous system: neurologic deterioration despite treatment.
De Tiège X, Van Bogaert P, Aeby A, Salmon I, Parpal H, Poppe AY, Maris C, Lanthier S
Pediatrics 2011 Apr;127(4):e1086-90. Epub 2011 Mar 14 doi: 10.1542/peds.2009-2729. PMID: 21402640
Nontraumatic pseudoaneurysm of the proximal ulnar artery with eosinophilia.
Sekino S, Takagi H, Kato T, Matsuno Y, Sekido Y, Umemoto T
J Vasc Surg 2005 Dec;42(6):1233-5. doi: 10.1016/j.jvs.2005.08.019. PMID: 16376222
Initial cutaneous manifestations consistent with mononeuropathy multiplex in Churg-Strauss syndrome.
Kawakami T, Soma Y, Kawasaki K, Kawase A, Mizoguchi M
Arch Dermatol 2005 Jul;141(7):873-8. doi: 10.1001/archderm.141.7.873. PMID: 16027304
Idiopathic granulomatous angiitis of the central nervous system in pregnancy: the first case report.
Barrionuevo MJ, Bronsteen RA, Eilender LM, Wright DJ, Goyert GL
J Matern Fetal Med 1997 Jan-Feb;6(1):58-60. doi: 10.1002/(SICI)1520-6661(199701/02)6:1<58::AID-MFM12>3.0.CO;2-I. PMID: 9029388
Granulomatous angiitis of the CNS.
Sandhu R, Alexander WS, Hornabrook RW, Stehbens WE
Arch Neurol 1979 Jul;36(7):433-5. doi: 10.1001/archneur.1979.00500430063009. PMID: 36873

Diagnosis

Granulomatous Angiitis: Twenty Years Later.
Younger DS
Neurol Clin 2019 May;37(2):267-277. doi: 10.1016/j.ncl.2019.01.011. PMID: 30952409
Primary Angiitis of the Central Nervous System.
Mandal J, Chung SA
Rheum Dis Clin North Am 2017 Nov;43(4):503-518. doi: 10.1016/j.rdc.2017.06.001. PMID: 29061238
Cerebral vasculitis.
Adams HP Jr
Handb Clin Neurol 2014;119:475-94. doi: 10.1016/B978-0-7020-4086-3.00031-X. PMID: 24365314
Angiitis of the central nervous system.
Lie JT
Curr Opin Rheumatol 1991 Feb;3(1):36-45. doi: 10.1097/00002281-199102000-00008. PMID: 2043451
Granulomatous angiitis of the CNS.
Sandhu R, Alexander WS, Hornabrook RW, Stehbens WE
Arch Neurol 1979 Jul;36(7):433-5. doi: 10.1001/archneur.1979.00500430063009. PMID: 36873

Therapy

Primary Angiitis of the Central Nervous System.
Mandal J, Chung SA
Rheum Dis Clin North Am 2017 Nov;43(4):503-518. doi: 10.1016/j.rdc.2017.06.001. PMID: 29061238
Foreign Body Emboli following Cerebrovascular Interventions: Clinical, Radiographic, and Histopathologic Features.
Shapiro M, Ollenschleger MD, Baccin C, Becske T, Spiegel GR, Wang Y, Song X, Raz E, Zumofen D, Potts MB, Nelson PK
AJNR Am J Neuroradiol 2015 Nov;36(11):2121-6. Epub 2015 Aug 20 doi: 10.3174/ajnr.A4415. PMID: 26294650Free PMC Article
Granulomatous angiitis of the CNS revealing a Hodgkin lymphoma.
Le Guennec L, Roos-Weil D, Mokhtari K, Chauvet D, Psimaras D, Reiner P, Demeret S, Bolgert F, Choquet S, Weiss N
Neurology 2013 Jan 15;80(3):323-4. Epub 2012 Dec 26 doi: 10.1212/WNL.0b013e31827deb26. PMID: 23269593
Reversible posterior leukoencephalopathy syndrome in p-ANCA-associated vasculitis.
Tajima Y, Matsumoto A
Intern Med 2006;45(20):1169-71. Epub 2006 Nov 15 doi: 10.2169/internalmedicine.45.1839. PMID: 17106164
Allergic granulomatous angiitis (Churg-Strauss syndrome).
Rosenberg TF, Medsger TA Jr, DeCicco FA, Fireman P
J Allergy Clin Immunol 1975 Jan;55(1):56-67. doi: 10.1016/s0091-6749(75)80008-x. PMID: 1110293

Prognosis

A CASE REPORT OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS.
Kozak N, Stakhova A
Georgian Med News 2023 Nov;(344):53-56. PMID: 38236099
Foreign Body Emboli following Cerebrovascular Interventions: Clinical, Radiographic, and Histopathologic Features.
Shapiro M, Ollenschleger MD, Baccin C, Becske T, Spiegel GR, Wang Y, Song X, Raz E, Zumofen D, Potts MB, Nelson PK
AJNR Am J Neuroradiol 2015 Nov;36(11):2121-6. Epub 2015 Aug 20 doi: 10.3174/ajnr.A4415. PMID: 26294650Free PMC Article
Primary angiitis of the central nervous system: neurologic deterioration despite treatment.
De Tiège X, Van Bogaert P, Aeby A, Salmon I, Parpal H, Poppe AY, Maris C, Lanthier S
Pediatrics 2011 Apr;127(4):e1086-90. Epub 2011 Mar 14 doi: 10.1542/peds.2009-2729. PMID: 21402640
Initial cutaneous manifestations consistent with mononeuropathy multiplex in Churg-Strauss syndrome.
Kawakami T, Soma Y, Kawasaki K, Kawase A, Mizoguchi M
Arch Dermatol 2005 Jul;141(7):873-8. doi: 10.1001/archderm.141.7.873. PMID: 16027304
Granulomatous angiitis of the CNS.
Sandhu R, Alexander WS, Hornabrook RW, Stehbens WE
Arch Neurol 1979 Jul;36(7):433-5. doi: 10.1001/archneur.1979.00500430063009. PMID: 36873

Clinical prediction guides

Fatigue-related brain white matter changes in granulomatosis with polyangiitis.
Basu N, Murray AD, Jones GT, Reid DM, Macfarlane GJ, Waiter GD
Rheumatology (Oxford) 2013 Aug;52(8):1429-34. Epub 2013 Apr 12 doi: 10.1093/rheumatology/ket135. PMID: 23584367
Head and neck manifestations of Wegener's granulomatosis.
Gottschlich S, Ambrosch P, Kramkowski D, Laudien M, Buchelt T, Gross WL, Hellmich B
Rhinology 2006 Dec;44(4):227-33. PMID: 17216737
An autopsy case of Wegener's granulomatosis with pachymeningitis.
Tojo J, Nishimaki T, Ohyanagi H, Saito A, Ohira H, Saka M, Kuroda M, Ishikawa H, Kasukawa R
Intern Med 1998 Aug;37(8):711-5. doi: 10.2169/internalmedicine.37.711. PMID: 9745862
Presence of autoantibody against nasal mucosal cells in patients with Wegener's granulomatosis.
Kamitani T, Yuasa K, Mori S
Int Arch Allergy Appl Immunol 1990;93(2-3):282-4. doi: 10.1159/000235315. PMID: 2099354
Churg-Strauss syndrome (allergic granulomatous angiitis). Neuro-ophthalmologic manifestations.
Weinstein JM, Chui H, Lane S, Corbett J, Towfighi J
Arch Ophthalmol 1983 Aug;101(8):1217-20. doi: 10.1001/archopht.1983.01040020219011. PMID: 6309124

Recent systematic reviews

The leukotriene receptor antagonist Montelukast can induce adverse skin reactions in asthmatic patients.
Di Salvo E, Patella V, Casciaro M, Gangemi S
Pulm Pharmacol Ther 2020 Feb;60:101875. Epub 2019 Dec 11 doi: 10.1016/j.pupt.2019.101875. PMID: 31837440

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