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Palate Squamous Cell Carcinoma

MedGen UID:
91154
•Concept ID:
C0349568
•
Neoplastic Process
Synonyms: Palate SCC; SCC - Squamous cell carcinoma of palate; SCC of Palate; SCC of the Palate; Squamous cell carcinoma of palate; Squamous Cell Carcinoma of Palate; Squamous Cell Carcinoma of the Palate
SNOMED CT: Squamous cell carcinoma of palate (276962007); SCC - Squamous cell carcinoma of palate (276962007)

Definition

A squamous cell carcinoma that arises from the hard or soft palate. [from NCI]

Professional guidelines

PubMed

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
ACR Appropriateness Criteria® ipsilateral radiation for squamous cell carcinoma of the tonsil.
Expert Panel on Radiation Oncology--Head & Neck Cancer:, Yeung AR, Garg MK, Lawson J, McDonald MW, Quon H, Ridge JA, Saba N, Salama JK, Smith RV, Yom SS, Beitler JJ; American College of Radiology
Head Neck 2012 May;34(5):613-6. Epub 2012 Jan 17 doi: 10.1002/hed.21993. PMID: 22250010
Dental considerations in management of head and neck cancer.
Hurst PS
Otolaryngol Clin North Am 1985 Aug;18(3):573-603. PMID: 3900878

Recent clinical studies

Etiology

Postoperative Radiotherapy in Advanced Stage Squamous Cell Carcinoma Requiring Maxillectomy.
Harley RJ, Spector ME, Wilke CT, Sridharan S
Otolaryngol Head Neck Surg 2024 Nov;171(5):1433-1440. Epub 2024 Jul 17 doi: 10.1002/ohn.896. PMID: 39016093
Neck dissection of cN0 maxillary oral squamous cell carcinoma: A study based on SEER database.
Yuan Z, Ren S, Ming H, Zhang X, Zhao Y, Tan X
J Stomatol Oral Maxillofac Surg 2024 Sep;125(4S):101947. Epub 2024 Jun 9 doi: 10.1016/j.jormas.2024.101947. PMID: 38857692
Free flap for soft palate reconstruction: long-term functional evaluation of a new technique.
Colliard A, Pincet L, Simon C, May L, Lambercy K
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1445-1452. Epub 2021 Jun 2 doi: 10.1007/s00405-021-06897-0. PMID: 34076726Free PMC Article
Radiation treatment of soft palate squamous cell carcinoma.
Rapp CT, Chera BS, Morris CG, Amdur RJ, Kirwan JM, Mendenhall WM
Head Neck 2020 Mar;42(3):530-538. Epub 2019 Nov 27 doi: 10.1002/hed.26035. PMID: 31773865
Prognostic factors in patients with soft palate squamous cell carcinoma.
Schernberg A, Canova C, Blanchard P, Gorphe P, Breuskin I, Mirghani H, Moya-Plana A, Janot F, Bidault F, Chargari C, Bellefqih S, Ruffier A, Even C, Nguyen F, Temam S, Tao Y
Head Neck 2019 May;41(5):1441-1449. Epub 2019 Jan 12 doi: 10.1002/hed.25598. PMID: 30636178

Diagnosis

Neck dissection of cN0 maxillary oral squamous cell carcinoma: A study based on SEER database.
Yuan Z, Ren S, Ming H, Zhang X, Zhao Y, Tan X
J Stomatol Oral Maxillofac Surg 2024 Sep;125(4S):101947. Epub 2024 Jun 9 doi: 10.1016/j.jormas.2024.101947. PMID: 38857692
Free flap for soft palate reconstruction: long-term functional evaluation of a new technique.
Colliard A, Pincet L, Simon C, May L, Lambercy K
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1445-1452. Epub 2021 Jun 2 doi: 10.1007/s00405-021-06897-0. PMID: 34076726Free PMC Article
Endovascular coiling of a mycotic external carotid artery pseudoaneurysm following pharyngolaryngectomy with a free jejunal graft.
Smelt JL, Alhamarneh O, Dyer JD, Liew L
J Laryngol Otol 2012 Feb;126(2):214-6. Epub 2011 Oct 18 doi: 10.1017/S0022215111002866. PMID: 22004875

Therapy

Endovascular coiling of a mycotic external carotid artery pseudoaneurysm following pharyngolaryngectomy with a free jejunal graft.
Smelt JL, Alhamarneh O, Dyer JD, Liew L
J Laryngol Otol 2012 Feb;126(2):214-6. Epub 2011 Oct 18 doi: 10.1017/S0022215111002866. PMID: 22004875

Prognosis

Postoperative Radiotherapy in Advanced Stage Squamous Cell Carcinoma Requiring Maxillectomy.
Harley RJ, Spector ME, Wilke CT, Sridharan S
Otolaryngol Head Neck Surg 2024 Nov;171(5):1433-1440. Epub 2024 Jul 17 doi: 10.1002/ohn.896. PMID: 39016093
Neck dissection of cN0 maxillary oral squamous cell carcinoma: A study based on SEER database.
Yuan Z, Ren S, Ming H, Zhang X, Zhao Y, Tan X
J Stomatol Oral Maxillofac Surg 2024 Sep;125(4S):101947. Epub 2024 Jun 9 doi: 10.1016/j.jormas.2024.101947. PMID: 38857692
Radiation treatment of soft palate squamous cell carcinoma.
Rapp CT, Chera BS, Morris CG, Amdur RJ, Kirwan JM, Mendenhall WM
Head Neck 2020 Mar;42(3):530-538. Epub 2019 Nov 27 doi: 10.1002/hed.26035. PMID: 31773865
Prognostic factors in patients with soft palate squamous cell carcinoma.
Schernberg A, Canova C, Blanchard P, Gorphe P, Breuskin I, Mirghani H, Moya-Plana A, Janot F, Bidault F, Chargari C, Bellefqih S, Ruffier A, Even C, Nguyen F, Temam S, Tao Y
Head Neck 2019 May;41(5):1441-1449. Epub 2019 Jan 12 doi: 10.1002/hed.25598. PMID: 30636178
A comparison of tongue and soft palate squamous cell carcinoma treated by primary surgery in terms of survival and quality of life outcomes.
Brown JS, Rogers SN, Lowe D
Int J Oral Maxillofac Surg 2006 Mar;35(3):208-14. Epub 2005 Dec 15 doi: 10.1016/j.ijom.2005.09.005. PMID: 16343850

Clinical prediction guides

Neck dissection of cN0 maxillary oral squamous cell carcinoma: A study based on SEER database.
Yuan Z, Ren S, Ming H, Zhang X, Zhao Y, Tan X
J Stomatol Oral Maxillofac Surg 2024 Sep;125(4S):101947. Epub 2024 Jun 9 doi: 10.1016/j.jormas.2024.101947. PMID: 38857692
Free flap for soft palate reconstruction: long-term functional evaluation of a new technique.
Colliard A, Pincet L, Simon C, May L, Lambercy K
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1445-1452. Epub 2021 Jun 2 doi: 10.1007/s00405-021-06897-0. PMID: 34076726Free PMC Article
Reverse facial-submental artery island flap for the reconstruction of maxillary defects after cancer ablation.
You YH, Chen WL, Wang YP, Liang J, Zhang DM
J Craniofac Surg 2009 Nov;20(6):2217-20. doi: 10.1097/SCS.0b013e3181bf84d7. PMID: 19934677
A comparison of tongue and soft palate squamous cell carcinoma treated by primary surgery in terms of survival and quality of life outcomes.
Brown JS, Rogers SN, Lowe D
Int J Oral Maxillofac Surg 2006 Mar;35(3):208-14. Epub 2005 Dec 15 doi: 10.1016/j.ijom.2005.09.005. PMID: 16343850

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