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Serous Tubal Intraepithelial Carcinoma

MedGen UID:
925121
•Concept ID:
C4287589
•
Neoplastic Process

Definition

A non-invasive serous carcinoma arising from the fallopian tube. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSerous Tubal Intraepithelial Carcinoma

Professional guidelines

PubMed

Consensus based recommendations for the diagnosis of serous tubal intraepithelial carcinoma: an international Delphi study.
Bogaerts JMA, van Bommel MHD, Hermens RPMG, Steenbeek MP, de Hullu JA, van der Laak JAWM; STIC consortium, Simons M
Histopathology 2023 Jul;83(1):67-79. Epub 2023 Mar 20 doi: 10.1111/his.14902. PMID: 36939551
Management of Preinvasive Lesions.
Patrono MG, Corzo C, Iniesta M, Ramirez PT
Clin Obstet Gynecol 2017 Dec;60(4):771-779. doi: 10.1097/GRF.0000000000000316. PMID: 28957950
Serous tubal intraepithelial carcinoma (STIC) - clinical impact and management.
Weinberger V, Bednarikova M, Cibula D, Zikan M
Expert Rev Anticancer Ther 2016 Dec;16(12):1311-1321. Epub 2016 Oct 22 doi: 10.1080/14737140.2016.1247699. PMID: 27732120

Recent clinical studies

Etiology

Morphologic and Molecular Heterogeneity of High-grade Serous Carcinoma Precursor Lesions.
Chien YW, Wang Y, Huang P, Lawson BC, Kolin DL, Chui MH, Vang R, Numan TA, Soong TR, Wang BG, Smith SA, Chen CL, Stone R, Douville C, Wang TL, Shih IM
Am J Surg Pathol 2024 Apr 1;48(4):475-486. Epub 2024 Feb 1 doi: 10.1097/PAS.0000000000002187. PMID: 38298022Free PMC Article
Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2.
Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S
Cells 2022 Feb 4;11(3) doi: 10.3390/cells11030539. PMID: 35159349Free PMC Article
Management of Preinvasive Lesions.
Patrono MG, Corzo C, Iniesta M, Ramirez PT
Clin Obstet Gynecol 2017 Dec;60(4):771-779. doi: 10.1097/GRF.0000000000000316. PMID: 28957950
Serous tubal intraepithelial carcinoma (STIC) - clinical impact and management.
Weinberger V, Bednarikova M, Cibula D, Zikan M
Expert Rev Anticancer Ther 2016 Dec;16(12):1311-1321. Epub 2016 Oct 22 doi: 10.1080/14737140.2016.1247699. PMID: 27732120
Ovarian cancer.
Matulonis UA, Sood AK, Fallowfield L, Howitt BE, Sehouli J, Karlan BY
Nat Rev Dis Primers 2016 Aug 25;2:16061. doi: 10.1038/nrdp.2016.61. PMID: 27558151Free PMC Article

Diagnosis

The Origin of Ovarian Cancer Species and Precancerous Landscape.
Shih IM, Wang Y, Wang TL
Am J Pathol 2021 Jan;191(1):26-39. Epub 2020 Oct 1 doi: 10.1016/j.ajpath.2020.09.006. PMID: 33011111Free PMC Article
Fallopian Tube Neoplasia and Mimics.
Kolin DL, Nucci MR
Surg Pathol Clin 2019 Jun;12(2):457-479. doi: 10.1016/j.path.2019.01.006. PMID: 31097111
MR Imaging-Pathologic Correlation in Ovarian Cancer.
Stein EB, Wasnik AP, Sciallis AP, Kamaya A, Maturen KE
Magn Reson Imaging Clin N Am 2017 Aug;25(3):545-562. Epub 2017 Apr 29 doi: 10.1016/j.mric.2017.03.004. PMID: 28668159
Serous tubal intraepithelial carcinoma (STIC) - clinical impact and management.
Weinberger V, Bednarikova M, Cibula D, Zikan M
Expert Rev Anticancer Ther 2016 Dec;16(12):1311-1321. Epub 2016 Oct 22 doi: 10.1080/14737140.2016.1247699. PMID: 27732120
Ovarian cancer.
Matulonis UA, Sood AK, Fallowfield L, Howitt BE, Sehouli J, Karlan BY
Nat Rev Dis Primers 2016 Aug 25;2:16061. doi: 10.1038/nrdp.2016.61. PMID: 27558151Free PMC Article

Therapy

Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis.
Steenbeek MP, van Bommel MHD, Bulten J, Hulsmann JA, Bogaerts J, Garcia C, Cun HT, Lu KH, van Beekhuizen HJ, Minig L, Gaarenstroom KN, Nobbenhuis M, Krajc M, Rudaitis V, Norquist BM, Swisher EM, Mourits MJE, Massuger LFAG, Hoogerbrugge N, Hermens RPMG, IntHout J, de Hullu JA
J Clin Oncol 2022 Jun 10;40(17):1879-1891. Epub 2022 Mar 18 doi: 10.1200/JCO.21.02016. PMID: 35302882Free PMC Article
Ovarian High-Grade Serous Carcinoma: Assessing Pathology for Site of Origin, Staging and Post-neoadjuvant Chemotherapy Changes.
Casey L, Singh N
Surg Pathol Clin 2019 Jun;12(2):515-528. doi: 10.1016/j.path.2019.01.007. PMID: 31097113
Ovarian cancer.
Matulonis UA, Sood AK, Fallowfield L, Howitt BE, Sehouli J, Karlan BY
Nat Rev Dis Primers 2016 Aug 25;2:16061. doi: 10.1038/nrdp.2016.61. PMID: 27558151Free PMC Article
Clinical outcomes in patients with isolated serous tubal intraepithelial carcinoma (STIC): A comprehensive review.
Patrono MG, Iniesta MD, Malpica A, Lu KH, Fernandez RO, Salvo G, Ramirez PT
Gynecol Oncol 2015 Dec;139(3):568-72. Epub 2015 Sep 25 doi: 10.1016/j.ygyno.2015.09.018. PMID: 26407480
Origin and molecular pathogenesis of ovarian high-grade serous carcinoma.
Kurman RJ
Ann Oncol 2013 Dec;24 Suppl 10:x16-21. doi: 10.1093/annonc/mdt463. PMID: 24265397

Prognosis

Morphologic and Molecular Heterogeneity of High-grade Serous Carcinoma Precursor Lesions.
Chien YW, Wang Y, Huang P, Lawson BC, Kolin DL, Chui MH, Vang R, Numan TA, Soong TR, Wang BG, Smith SA, Chen CL, Stone R, Douville C, Wang TL, Shih IM
Am J Surg Pathol 2024 Apr 1;48(4):475-486. Epub 2024 Feb 1 doi: 10.1097/PAS.0000000000002187. PMID: 38298022Free PMC Article
Pathological findings and long-term prognosis in Korean BRCA1/2 mutation carriers undergoing risk-reducing salpingo-oophorectomy.
Kang OJ, Lee SW, Kim JH, Park JY, Suh DS, Kim DY, Kim JH, Kim YM, Kim YT
Int J Gynecol Cancer 2023 Nov 6;33(11):1743-1749. doi: 10.1136/ijgc-2023-004618. PMID: 37541685
Recommendations for diagnosing STIC: a systematic review and meta-analysis.
Bogaerts JMA, Steenbeek MP, van Bommel MHD, Bulten J, van der Laak JAWM, de Hullu JA, Simons M
Virchows Arch 2022 Apr;480(4):725-737. Epub 2021 Dec 1 doi: 10.1007/s00428-021-03244-w. PMID: 34850262Free PMC Article
TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer.
Lecker LSM, Berlato C, Maniati E, Delaine-Smith R, Pearce OMT, Heath O, Nichols SJ, Trevisan C, Novak M, McDermott J, Brenton JD, Cutillas PR, Rajeeve V, Hennino A, Drapkin R, Loessner D, Balkwill FR
Cancer Res 2021 Nov 15;81(22):5706-5719. Epub 2021 Sep 24 doi: 10.1158/0008-5472.CAN-21-0536. PMID: 34561272Free PMC Article
Serous tubal intraepithelial carcinoma (STIC) - clinical impact and management.
Weinberger V, Bednarikova M, Cibula D, Zikan M
Expert Rev Anticancer Ther 2016 Dec;16(12):1311-1321. Epub 2016 Oct 22 doi: 10.1080/14737140.2016.1247699. PMID: 27732120

Clinical prediction guides

Morphologic and Molecular Heterogeneity of High-grade Serous Carcinoma Precursor Lesions.
Chien YW, Wang Y, Huang P, Lawson BC, Kolin DL, Chui MH, Vang R, Numan TA, Soong TR, Wang BG, Smith SA, Chen CL, Stone R, Douville C, Wang TL, Shih IM
Am J Surg Pathol 2024 Apr 1;48(4):475-486. Epub 2024 Feb 1 doi: 10.1097/PAS.0000000000002187. PMID: 38298022Free PMC Article
Histopathologic and Preneoplastic Changes in Tubal Ligation Materials.
Ömeroğlu E, Ünlü Y, Uğur Kılınç AN, Günler T, Günenc O
Medicina (Kaunas) 2023 Dec 4;59(12) doi: 10.3390/medicina59122117. PMID: 38138220Free PMC Article
Frequency of serous tubal intraepithelial carcinoma (STIC) in patients with high grade serous ovarian cancer.
Byun JM, Cho HJ, Lee DS, Yoon HK, Kim YN, Im DH, Kim DH, Lee KB, Sung MS, Jeong DH
Taiwan J Obstet Gynecol 2023 Jan;62(1):107-111. doi: 10.1016/j.tjog.2022.09.006. PMID: 36720520
Ovarian High-Grade Serous Carcinoma: Assessing Pathology for Site of Origin, Staging and Post-neoadjuvant Chemotherapy Changes.
Casey L, Singh N
Surg Pathol Clin 2019 Jun;12(2):515-528. doi: 10.1016/j.path.2019.01.007. PMID: 31097113
Management of Preinvasive Lesions.
Patrono MG, Corzo C, Iniesta M, Ramirez PT
Clin Obstet Gynecol 2017 Dec;60(4):771-779. doi: 10.1097/GRF.0000000000000316. PMID: 28957950

Recent systematic reviews

Outcome and Management of Serous Tubal Intraepithelial Carcinoma Following Opportunistic Salpingectomy: Systematic Review and Meta-Analysis.
Ruel-Laliberté J, Kasasni SM, Oprea D, Viau M
J Obstet Gynaecol Can 2022 Nov;44(11):1174-1180. Epub 2022 Sep 12 doi: 10.1016/j.jogc.2022.08.018. PMID: 36099965
Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis.
Steenbeek MP, van Bommel MHD, Bulten J, Hulsmann JA, Bogaerts J, Garcia C, Cun HT, Lu KH, van Beekhuizen HJ, Minig L, Gaarenstroom KN, Nobbenhuis M, Krajc M, Rudaitis V, Norquist BM, Swisher EM, Mourits MJE, Massuger LFAG, Hoogerbrugge N, Hermens RPMG, IntHout J, de Hullu JA
J Clin Oncol 2022 Jun 10;40(17):1879-1891. Epub 2022 Mar 18 doi: 10.1200/JCO.21.02016. PMID: 35302882Free PMC Article
Recommendations for diagnosing STIC: a systematic review and meta-analysis.
Bogaerts JMA, Steenbeek MP, van Bommel MHD, Bulten J, van der Laak JAWM, de Hullu JA, Simons M
Virchows Arch 2022 Apr;480(4):725-737. Epub 2021 Dec 1 doi: 10.1007/s00428-021-03244-w. PMID: 34850262Free PMC Article
Pathological findings following risk-reducing salpingo-oophorectomy in BRCA mutation carriers: A systematic review and meta-analysis.
Cheng A, Li L, Wu M, Lang J
Eur J Surg Oncol 2020 Jan;46(1):139-147. Epub 2019 Sep 5 doi: 10.1016/j.ejso.2019.09.002. PMID: 31521389
Outcome and Prognostic Impact of Surgical Staging in Serous Tubal Intraepithelial Carcinoma: A Cohort Study and Systematic Review.
Van der Hoeven NMA, Van Wijk K, Bonfrer SE, Beltman JJ, Louwe LA, De Kroon CD, Van Asperen CJ, Gaarenstroom KN
Clin Oncol (R Coll Radiol) 2018 Aug;30(8):463-471. Epub 2018 Apr 22 doi: 10.1016/j.clon.2018.03.036. PMID: 29691126

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