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Vulvar Hidradenoma Papilliferum

MedGen UID:
925533
Concept ID:
C4288001
Neoplastic Process
Synonym: Vulvar Papillary Hidradenoma

Definition

A benign glandular neoplasm that arises from the vulva. It presents as a mass or cystic lesion in or adjacent to the interlabial sulcus. It is characterized by the presence of complex branching papillae with fibrovascular stalks, lined by uniform columnar epithelial secretory cells and myoepithelial cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Hidradenoma Papilliferum

Professional guidelines

PubMed

Pfarr N, Allgäuer M, Steiger K, Weichert W, Schirmacher P, Noske A, Stenzinger A
Pathology 2019 Jun;51(4):362-368. Epub 2019 Apr 19 doi: 10.1016/j.pathol.2019.01.010. PMID: 31010589
Omole F, Simmons BJ, Hacker Y
Am Fam Physician 2003 Jul 1;68(1):135-40. PMID: 12887119

Recent clinical studies

Etiology

Tosti G, Salvini C, Barisani A, Grazi R, Pirola S, Cantisani C, Vaccari S, Madnani N
Clin Exp Dermatol 2020 Dec;45(8):1035-1039. Epub 2020 Oct 6 doi: 10.1111/ced.14254. PMID: 32356582
Konstantinova AM, Shelekhova KV, Imyanitov EN, Iyevleva A, Kacerovska D, Michal M, Kazakov DV
Am J Dermatopathol 2017 May;39(5):358-362. doi: 10.1097/DAD.0000000000000725. PMID: 28291131
El-Khoury J, Renald MH, Plantier F, Avril MF, Moyal-Barracco M
J Am Acad Dermatol 2016 Aug;75(2):380-4. Epub 2016 Mar 2 doi: 10.1016/j.jaad.2016.01.034. PMID: 26944596
Baker GM, Selim MA, Hoang MP
Arch Pathol Lab Med 2013 Sep;137(9):1237-46. doi: 10.5858/arpa.2012-0434-OA. PMID: 23991738
Virgili A, Marzola A, Corazza M
J Reprod Med 2000 Aug;45(8):616-8. PMID: 10986678

Diagnosis

Birge O, Bakır MS, Karadag C, Eldarova Z, Simsek T
J Med Case Rep 2021 Apr 13;15(1):162. doi: 10.1186/s13256-021-02786-6. PMID: 33845900Free PMC Article
Tosti G, Salvini C, Barisani A, Grazi R, Pirola S, Cantisani C, Vaccari S, Madnani N
Clin Exp Dermatol 2020 Dec;45(8):1035-1039. Epub 2020 Oct 6 doi: 10.1111/ced.14254. PMID: 32356582
Goto K, Maeda D, Kudo-Asabe Y, Hibiya T, Hayashi A, Fukayama M, Ohashi K, Goto A
J Clin Pathol 2017 May;70(5):424-427. Epub 2016 Oct 14 doi: 10.1136/jclinpath-2016-204003. PMID: 27742746
Kazakov DV, Spagnolo DV, Kacerovska D, Michal M
Adv Anat Pathol 2011 Jan;18(1):1-28. doi: 10.1097/PAP.0b013e318202eba5. PMID: 21169735
Omole F, Simmons BJ, Hacker Y
Am Fam Physician 2003 Jul 1;68(1):135-40. PMID: 12887119

Prognosis

Konstantinova AM, Shelekhova KV, Imyanitov EN, Iyevleva A, Kacerovska D, Michal M, Kazakov DV
Am J Dermatopathol 2017 May;39(5):358-362. doi: 10.1097/DAD.0000000000000725. PMID: 28291131
Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov DV
Am J Dermatopathol 2016 Aug;38(8):598-607. doi: 10.1097/DAD.0000000000000495. PMID: 26863059
Pfarr N, Sinn HP, Klauschen F, Flechtenmacher C, Bockmayr M, Ridinger K, von Winterfeld M, Warth A, Lorenz K, Budczies J, Penzel R, Lennerz JK, Endris V, Weichert W, Stenzinger A
Genes Chromosomes Cancer 2016 Feb;55(2):113-9. Epub 2015 Oct 23 doi: 10.1002/gcc.22315. PMID: 26493284
Sington J, Chandrapala R, Manek S, Hollowood K
Am J Dermatopathol 2006 Aug;28(4):322-6. doi: 10.1097/00000372-200608000-00005. PMID: 16871035

Clinical prediction guides

Pfarr N, Allgäuer M, Steiger K, Weichert W, Schirmacher P, Noske A, Stenzinger A
Pathology 2019 Jun;51(4):362-368. Epub 2019 Apr 19 doi: 10.1016/j.pathol.2019.01.010. PMID: 31010589
Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov DV
Am J Dermatopathol 2016 Aug;38(8):598-607. doi: 10.1097/DAD.0000000000000495. PMID: 26863059
Sington J, Chandrapala R, Manek S, Hollowood K
Am J Dermatopathol 2006 Aug;28(4):322-6. doi: 10.1097/00000372-200608000-00005. PMID: 16871035
Handa Y, Yamanaka N, Inagaki H, Tomita Y
Dermatol Surg 2003 Jul;29(7):790-2. doi: 10.1046/j.1524-4725.2003.29201.x. PMID: 12828711
van der Putte SC
Int J Gynecol Pathol 1994 Apr;13(2):150-60. doi: 10.1097/00004347-199404000-00009. PMID: 8005737

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