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Anaplastic oligoastrocytoma

MedGen UID:
96556
Concept ID:
C0431108
Neoplastic Process
Synonyms: aMOA; Anaplastic Mixed Glioma; anaplastic mixed glioma; Anaplastic Oligoastrocytoma; anaplastic oligoastrocytoma; Anaplastic Oligoastrocytoma, NOS; Anaplastic Oligoastrocytoma, Not Otherwise Specified; AOAST; WHO Grade 3 Mixed Glioma; WHO Grade III Mixed Glioma; WHO grade III mixed glioma
SNOMED CT: Anaplastic oligoastrocytoma (253072003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016703
Orphanet: ORPHA251663

Definition

A rare and aggressive glial tumor of the central nervous system, that usually presents in adults with seizures, is most often located in the cerebral hemispheres and that is associated with a very poor prognosis. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic oligoastrocytoma
Follow this link to review classifications for Anaplastic oligoastrocytoma in Orphanet.

Professional guidelines

PubMed

Levin VA, Ictech SE, Hess KR
CNS Oncol 2018 Apr;7(2):CNS16. Epub 2018 Jan 30 doi: 10.2217/cns-2017-0031. PMID: 29378419Free PMC Article
Le Rhun E, Taillibert S, Chamberlain MC
Expert Rev Neurother 2015 Jun;15(6):601-20. Epub 2015 May 2 doi: 10.1586/14737175.2015.1042455. PMID: 25936680
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732

Recent clinical studies

Etiology

Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
McNamara MG, Jiang H, Lim-Fat MJ, Sahebjam S, Kiehl TR, Karamchandani J, Coire C, Chung C, Millar BA, Laperriere N, Mason WP
Can J Neurol Sci 2017 May;44(3):288-294. doi: 10.1017/cjn.2016.420. PMID: 28488951
Le Rhun E, Taillibert S, Chamberlain MC
Expert Rev Neurother 2015 Jun;15(6):601-20. Epub 2015 May 2 doi: 10.1586/14737175.2015.1042455. PMID: 25936680
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Diagnosis

Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Le Rhun E, Taillibert S, Chamberlain MC
Expert Rev Neurother 2015 Jun;15(6):601-20. Epub 2015 May 2 doi: 10.1586/14737175.2015.1042455. PMID: 25936680
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Therapy

Levin VA, Ictech SE, Hess KR
CNS Oncol 2018 Apr;7(2):CNS16. Epub 2018 Jan 30 doi: 10.2217/cns-2017-0031. PMID: 29378419Free PMC Article
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, Curran W, Mehta M
J Clin Oncol 2013 Jan 20;31(3):337-43. Epub 2012 Oct 15 doi: 10.1200/JCO.2012.43.2674. PMID: 23071247Free PMC Article
Bromberg JE, van den Bent MJ
Oncologist 2009 Feb;14(2):155-63. Epub 2009 Jan 31 doi: 10.1634/theoncologist.2008-0248. PMID: 19182242
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Prognosis

Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
Bromberg JE, van den Bent MJ
Oncologist 2009 Feb;14(2):155-63. Epub 2009 Jan 31 doi: 10.1634/theoncologist.2008-0248. PMID: 19182242
Buckner JC, O'Fallon JR, Dinapoli RP, Schomberg PJ, Farr G, Schaefer P, Giannini C, Scheithauer BW, Ballman KV
J Neurooncol 2007 Sep;84(3):279-86. Epub 2007 Apr 13 doi: 10.1007/s11060-007-9370-y. PMID: 17431544
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Clinical prediction guides

Balañá C, Alonso M, Hernandez-Lain A, Hernandez A, Perez-Segura P, Pineda E, Ramos A, Sanchez AR, Teixidor P, Verger E, Benavides M
Clin Transl Oncol 2018 Jan;20(1):16-21. Epub 2017 Oct 20 doi: 10.1007/s12094-017-1762-7. PMID: 29058264Free PMC Article
Anderson MD, Gilbert MR
J Natl Compr Canc Netw 2014 May;12(5):665-72. doi: 10.6004/jnccn.2014.0070. PMID: 24812135
Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, Curran W, Mehta M
J Clin Oncol 2013 Jan 20;31(3):337-43. Epub 2012 Oct 15 doi: 10.1200/JCO.2012.43.2674. PMID: 23071247Free PMC Article
Stupp R, Hegi ME, Gilbert MR, Chakravarti A
J Clin Oncol 2007 Sep 10;25(26):4127-36. doi: 10.1200/JCO.2007.11.8554. PMID: 17827463
Yi L, Zhou ZH, Ping YF, Chen JH, Yao XH, Feng H, Lu JY, Wang JM, Bian XW
Mod Pathol 2007 Oct;20(10):1061-8. Epub 2007 Jul 27 doi: 10.1038/modpathol.3800942. PMID: 17660801

Recent systematic reviews

Zhang L, Wu X, Xu T, Luo C, Qian J, Lu Y
J Cancer Res Clin Oncol 2013 May;139(5):719-26. Epub 2013 Feb 10 doi: 10.1007/s00432-013-1387-3. PMID: 23397358

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