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Benign basal cell neoplasm

MedGen UID:
96885
•Concept ID:
C0474802
•
Neoplastic Process
Synonyms: Benign Basal Cell Neoplasm; benign basal cell neoplasm; Benign basal cell tumor; Benign Basal Cell Tumor; benign basal cell tumor; benign basal cell tumour
SNOMED CT: Benign basal cell tumor (252996004)
 
Monarch Initiative: MONDO:0020805

Definition

A neoplasm composed of basal cells that remains localized and does not metastasize to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign basal cell neoplasm

Professional guidelines

PubMed

S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675
Diagnosis and management of benign lumps and bumps in childhood.
Price HN, Zaenglein AL
Curr Opin Pediatr 2007 Aug;19(4):420-4. doi: 10.1097/MOP.0b013e328224b8ee. PMID: 17630606
Endocervical adenocarcinoma and its variants: their morphology and differential diagnosis.
Young RH, Clement PB
Histopathology 2002 Sep;41(3):185-207. doi: 10.1046/j.1365-2559.2002.01462.x. PMID: 12207781

Recent clinical studies

Etiology

Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
Benign mimics of prostate cancer.
Egevad L, Delahunt B, Furusato B, Tsuzuki T, Yaxley J, Samaratunga H
Pathology 2021 Jan;53(1):26-35. Epub 2020 Oct 16 doi: 10.1016/j.pathol.2020.08.006. PMID: 33070957
Cutaneous sebaceous carcinoma.
Wu A, Rajak SN, Huilgol SC, James C, Selva D
Australas J Dermatol 2020 Aug;61(3):e283-e292. Epub 2020 Jan 19 doi: 10.1111/ajd.13234. PMID: 31956994
Pathology of eyelid tumors.
Pe'er J
Indian J Ophthalmol 2016 Mar;64(3):177-90. doi: 10.4103/0301-4738.181752. PMID: 27146927Free PMC Article
Matter of margins.
Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680

Diagnosis

Dermatoscopy of Neoplastic Skin Lesions: Recent Advances, Updates, and Revisions.
Weber P, Tschandl P, Sinz C, Kittler H
Curr Treat Options Oncol 2018 Sep 20;19(11):56. doi: 10.1007/s11864-018-0573-6. PMID: 30238167Free PMC Article
Pilomatrixoma: A Comprehensive Review of the Literature.
Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102
Histologic Mimics of Basal Cell Carcinoma.
Stanoszek LM, Wang GY, Harms PW
Arch Pathol Lab Med 2017 Nov;141(11):1490-1502. doi: 10.5858/arpa.2017-0222-RA. PMID: 29072946
Benign follicular tumors.
Tellechea O, Cardoso JC, Reis JP, Ramos L, Gameiro AR, Coutinho I, Baptista AP
An Bras Dermatol 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114. PMID: 26734858Free PMC Article
Pink lesions.
Giacomel J, Zalaudek I
Dermatol Clin 2013 Oct;31(4):649-78, ix. doi: 10.1016/j.det.2013.06.005. PMID: 24075552

Therapy

Sebaceous Carcinoma: A Review of the Scientific Literature.
Knackstedt T, Samie FH
Curr Treat Options Oncol 2017 Aug;18(8):47. doi: 10.1007/s11864-017-0490-0. PMID: 28681210
Clinical relevance and implications of HPV-induced neoplasia in different anatomical locations.
Prigge ES, von Knebel Doeberitz M, Reuschenbach M
Mutat Res Rev Mutat Res 2017 Apr-Jun;772:51-66. Epub 2016 Jun 22 doi: 10.1016/j.mrrev.2016.06.005. PMID: 28528690
Imiquimod in dermatology: an overview.
Hanna E, Abadi R, Abbas O
Int J Dermatol 2016 Aug;55(8):831-44. doi: 10.1111/ijd.13235. PMID: 27387373
Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016
Granuloma faciale.
Khaled A, Jones M, Zermani R, Fazaa B, Baccouche K, Ben Jilani S, Kamoun MR
Pathologica 2007 Oct;99(5):306-8. PMID: 18354952

Prognosis

Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
Pilomatrixoma: A Comprehensive Review of the Literature.
Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102
Imiquimod in dermatology: an overview.
Hanna E, Abadi R, Abbas O
Int J Dermatol 2016 Aug;55(8):831-44. doi: 10.1111/ijd.13235. PMID: 27387373
Matter of margins.
Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680
Nail tumors.
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590

Clinical prediction guides

Analysis of the Clinical Relevance of Histological Classification of Benign Epithelial Salivary Gland Tumours.
Hellquist H, Paiva-Correia A, Vander Poorten V, Quer M, Hernandez-Prera JC, Andreasen S, Zbären P, Skalova A, Rinaldo A, Ferlito A
Adv Ther 2019 Aug;36(8):1950-1974. Epub 2019 Jun 17 doi: 10.1007/s12325-019-01007-3. PMID: 31209701Free PMC Article
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Pilomatrixoma: A Comprehensive Review of the Literature.
Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102
Dermoscopy for the family physician.
Marghoob AA, Usatine RP, Jaimes N
Am Fam Physician 2013 Oct 1;88(7):441-50. PMID: 24134084
Penile melanosis.
Revuz J, Clerici T
J Am Acad Dermatol 1989 Apr;20(4):567-70. doi: 10.1016/s0190-9622(89)70064-5. PMID: 2715403

Recent systematic reviews

Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.
Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546Free PMC Article
Zebras in Foreskin Dermatopathology: A Review.
Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956
VivaScope® 1500 and 3000 systems for detecting and monitoring skin lesions: a systematic review and economic evaluation.
Edwards SJ, Mavranezouli I, Osei-Assibey G, Marceniuk G, Wakefield V, Karner C
Health Technol Assess 2016 Jul;20(58):1-260. doi: 10.3310/hta20580. PMID: 27483991Free PMC Article
Review of pediatric head and neck pilomatrixoma.
Schwarz Y, Pitaro J, Waissbluth S, Daniel SJ
Int J Pediatr Otorhinolaryngol 2016 Jun;85:148-53. Epub 2016 Mar 28 doi: 10.1016/j.ijporl.2016.03.026. PMID: 27240514
Non-syndromic and syndromic keratocystic odontogenic tumors: systematic review and meta-analysis of recurrences.
Antonoglou GN, Sándor GK, Koidou VP, Papageorgiou SN
J Craniomaxillofac Surg 2014 Oct;42(7):e364-71. Epub 2014 Apr 1 doi: 10.1016/j.jcms.2014.03.020. PMID: 24815763

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