U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign basal cell neoplasm

MedGen UID:
96885
•Concept ID:
C0474802
•
Neoplastic Process
Synonyms: benign basal cell neoplasm; Benign basal cell tumor; benign basal cell tumor; benign basal cell tumour
SNOMED CT: Benign basal cell tumor (252996004)
 
Monarch Initiative: MONDO:0020805

Definition

A neoplasm composed of basal cells that remains localized and does not metastasize to other anatomic sites. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign basal cell neoplasm

Professional guidelines

PubMed

Diagnosis and treatment of malignant eyelid tumors.
Gniesmer S, Sonntag SR, Schiemenz C, Ranjbar M, Heindl LM, Varde MA, Emmert S, Grisanti S, Kakkassery V
Ophthalmologie 2024 Jan;121(Suppl 1):33-39. Epub 2023 Oct 18 doi: 10.1007/s00347-023-01945-y. PMID: 37851118
Clinical Signs for Differential Diagnosis of Eyelid Tumours.
Kopecky A, Rokohl AC, Gaca PJ, Matos PAW, Nemcansky J, Heindl LM
Klin Monbl Augenheilkd 2023 Jan;240(1):13-23. Epub 2023 Jan 27 doi: 10.1055/a-1996-0950. PMID: 36706766
S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675

Recent clinical studies

Etiology

PRAME Updated: Diagnostic, Prognostic, and Therapeutic Role in Skin Cancer.
Cassalia F, Danese A, Tudurachi I, Federico S, Zambello A, Guidotti A, Franceschin L, Bolzon A, Naldi L, Belloni Fortina A
Int J Mol Sci 2024 Jan 27;25(3) doi: 10.3390/ijms25031582. PMID: 38338862Free PMC Article
Genetics of adnexal tumors: An update.
Kervarrec T, Sohier P, Pissaloux D, de la Fouchardiere A, Cribier B, Battistella M, Macagno N
Ann Dermatol Venereol 2023 Sep;150(3):202-207. Epub 2023 Jun 1 doi: 10.1016/j.annder.2023.03.003. PMID: 37270318
Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
Cutaneous sebaceous carcinoma.
Wu A, Rajak SN, Huilgol SC, James C, Selva D
Australas J Dermatol 2020 Aug;61(3):e283-e292. Epub 2020 Jan 19 doi: 10.1111/ajd.13234. PMID: 31956994
Matter of margins.
Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680

Diagnosis

Dermatoscopy of Neoplastic Skin Lesions: Recent Advances, Updates, and Revisions.
Weber P, Tschandl P, Sinz C, Kittler H
Curr Treat Options Oncol 2018 Sep 20;19(11):56. doi: 10.1007/s11864-018-0573-6. PMID: 30238167Free PMC Article
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Histologic Mimics of Basal Cell Carcinoma.
Stanoszek LM, Wang GY, Harms PW
Arch Pathol Lab Med 2017 Nov;141(11):1490-1502. doi: 10.5858/arpa.2017-0222-RA. PMID: 29072946
Benign follicular tumors.
Tellechea O, Cardoso JC, Reis JP, Ramos L, Gameiro AR, Coutinho I, Baptista AP
An Bras Dermatol 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114. PMID: 26734858Free PMC Article
Pink lesions.
Giacomel J, Zalaudek I
Dermatol Clin 2013 Oct;31(4):649-78, ix. doi: 10.1016/j.det.2013.06.005. PMID: 24075552

Therapy

Sebaceous Carcinoma: A Review of the Scientific Literature.
Knackstedt T, Samie FH
Curr Treat Options Oncol 2017 Aug;18(8):47. doi: 10.1007/s11864-017-0490-0. PMID: 28681210
Clinical relevance and implications of HPV-induced neoplasia in different anatomical locations.
Prigge ES, von Knebel Doeberitz M, Reuschenbach M
Mutat Res Rev Mutat Res 2017 Apr-Jun;772:51-66. Epub 2016 Jun 22 doi: 10.1016/j.mrrev.2016.06.005. PMID: 28528690
Imiquimod in dermatology: an overview.
Hanna E, Abadi R, Abbas O
Int J Dermatol 2016 Aug;55(8):831-44. doi: 10.1111/ijd.13235. PMID: 27387373
Granuloma faciale.
Khaled A, Jones M, Zermani R, Fazaa B, Baccouche K, Ben Jilani S, Kamoun MR
Pathologica 2007 Oct;99(5):306-8. PMID: 18354952
Halo dermatitis around tumours.
Tegner E, Björnberg A, Jonsson N
Acta Derm Venereol 1990;70(1):31-4. PMID: 1967868

Prognosis

PRAME Updated: Diagnostic, Prognostic, and Therapeutic Role in Skin Cancer.
Cassalia F, Danese A, Tudurachi I, Federico S, Zambello A, Guidotti A, Franceschin L, Bolzon A, Naldi L, Belloni Fortina A
Int J Mol Sci 2024 Jan 27;25(3) doi: 10.3390/ijms25031582. PMID: 38338862Free PMC Article
Pilomatrixoma: A Comprehensive Review of the Literature.
Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102
Matter of margins.
Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680
Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.
Di Florio A, Sancho V, Moreno P, Delle Fave G, Jensen RT
Biochim Biophys Acta 2013 Mar;1833(3):573-82. Epub 2012 Dec 4 doi: 10.1016/j.bbamcr.2012.11.021. PMID: 23220008Free PMC Article
Cutaneous paraneoplasia.
Ramos-E-Silva M, Carvalho JC, Carneiro SC
Clin Dermatol 2011 Sep-Oct;29(5):541-7. doi: 10.1016/j.clindermatol.2010.09.022. PMID: 21855730

Clinical prediction guides

Pitfalls in Salivary Gland Cytology.
Saoud C, Bailey GE, Graham A, Bonilla LM, Sanchez SI, Maleki Z
Acta Cytol 2024;68(3):194-205. Epub 2024 Feb 28 doi: 10.1159/000538069. PMID: 38417405
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Pilomatrixoma: A Comprehensive Review of the Literature.
Jones CD, Ho W, Robertson BF, Gunn E, Morley S
Am J Dermatopathol 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118. PMID: 30119102
Dermoscopy of chondrodermatitis nodularis helicis.
García-García B, Munguía-Calzada P, Aubán-Pariente J, Junceda-Antuña S, Zaballos P, Argenziano G, Vázquez-López F
Arch Dermatol Res 2018 Sep;310(7):551-560. Epub 2018 Jun 20 doi: 10.1007/s00403-018-1844-6. PMID: 29926164
Penile melanosis.
Revuz J, Clerici T
J Am Acad Dermatol 1989 Apr;20(4):567-70. doi: 10.1016/s0190-9622(89)70064-5. PMID: 2715403

Recent systematic reviews

Systematic review of benefits and practical challenges for application of Mohs surgery for oral tumors.
Hussain A, Kim EY, Khachemoune A
Arch Dermatol Res 2023 Nov;315(9):2479-2484. Epub 2023 May 12 doi: 10.1007/s00403-023-02632-3. PMID: 37173597
Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.
Lai M, Muscianese M, Piana S, Chester J, Borsari S, Paolino G, Pellacani G, Longo C, Pampena R
J Eur Acad Dermatol Venereol 2022 Sep;36(9):1524-1540. Epub 2022 May 25 doi: 10.1111/jdv.18210. PMID: 35536546Free PMC Article
Zebras in Foreskin Dermatopathology: A Review.
Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956
Review of pediatric head and neck pilomatrixoma.
Schwarz Y, Pitaro J, Waissbluth S, Daniel SJ
Int J Pediatr Otorhinolaryngol 2016 Jun;85:148-53. Epub 2016 Mar 28 doi: 10.1016/j.ijporl.2016.03.026. PMID: 27240514
Non-syndromic and syndromic keratocystic odontogenic tumors: systematic review and meta-analysis of recurrences.
Antonoglou GN, Sándor GK, Koidou VP, Papageorgiou SN
J Craniomaxillofac Surg 2014 Oct;42(7):e364-71. Epub 2014 Apr 1 doi: 10.1016/j.jcms.2014.03.020. PMID: 24815763

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...