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Hypertrophic lichen planus

MedGen UID:
9756
Concept ID:
C0023649
Disease or Syndrome
Synonyms: Hypertrophic Lichen Planus; hypertrophic lichen planus; Lichen planus hypertrophicus; lichen planus hypertrophicus
SNOMED CT: Hypertrophic lichen planus (68266006); Lichen planus hypertrophicus (68266006)
 
Monarch Initiative: MONDO:0021377

Definition

A form of lichen planus that is characterized by plaques of markedly thickened skin that is often extremely pruritic and localized to the lower legs. It can result in permanent pigmentation and scarring. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypertrophic lichen planus

Professional guidelines

PubMed

Whittington CP, Saleh JS, Bresler SC, Patel RM
Arch Pathol Lab Med 2024 Jun 1;148(6):659-665. doi: 10.5858/arpa.2022-0515-RA. PMID: 37327190
Idriss MH, Barbosa N, Chang MB, Gibson L, Baum CL, Vidal NY
Int J Dermatol 2022 Dec;61(12):1527-1531. Epub 2022 Jun 29 doi: 10.1111/ijd.16321. PMID: 35766459
Majid I
J Am Acad Dermatol 2017 Sep;77(3):e67-e68. doi: 10.1016/j.jaad.2017.05.005. PMID: 28807121

Recent clinical studies

Etiology

Sanchez I, Ibraheim MK, Lee BA, Kraus CN, Elsensohn A
Am J Dermatopathol 2023 Dec 1;45(12):820-821. doi: 10.1097/DAD.0000000000002550. PMID: 37883982
Idriss MH, Barbosa N, Chang MB, Gibson L, Baum CL, Vidal NY
Int J Dermatol 2022 Dec;61(12):1527-1531. Epub 2022 Jun 29 doi: 10.1111/ijd.16321. PMID: 35766459
Astudillo MG, Hoang MP, Nazarian RM, Foreman RK
Am J Dermatopathol 2021 May 1;43(5):349-355. doi: 10.1097/DAD.0000000000001776. PMID: 33395040
Knackstedt TJ, Collins LK, Li Z, Yan S, Samie FH
Dermatol Surg 2015 Dec;41(12):1411-8. doi: 10.1097/DSS.0000000000000565. PMID: 26551772
Alomari A, McNiff JM
J Cutan Pathol 2014 Apr;41(4):347-52. Epub 2014 Jan 31 doi: 10.1111/cup.12275. PMID: 24325780

Diagnosis

Whittington CP, Saleh JS, Bresler SC, Patel RM
Arch Pathol Lab Med 2024 Jun 1;148(6):659-665. doi: 10.5858/arpa.2022-0515-RA. PMID: 37327190
Sanchez I, Ibraheim MK, Lee BA, Kraus CN, Elsensohn A
Am J Dermatopathol 2023 Dec 1;45(12):820-821. doi: 10.1097/DAD.0000000000002550. PMID: 37883982
Idriss MH, Barbosa N, Chang MB, Gibson L, Baum CL, Vidal NY
Int J Dermatol 2022 Dec;61(12):1527-1531. Epub 2022 Jun 29 doi: 10.1111/ijd.16321. PMID: 35766459
Chapman S, Ashack K, Dapprich DC
Cutis 2021 Jan;107(1):E10-E11. doi: 10.12788/cutis.0160. PMID: 33651868
Seiringer P, Lauffer F, Pilz AC, Boehmer D, Biedermann T, Eyerich K
Acta Derm Venereol 2020 Jul 28;100(14):adv00220. doi: 10.2340/00015555-3585. PMID: 32618349Free PMC Article

Therapy

Idriss MH, Barbosa N, Chang MB, Gibson L, Baum CL, Vidal NY
Int J Dermatol 2022 Dec;61(12):1527-1531. Epub 2022 Jun 29 doi: 10.1111/ijd.16321. PMID: 35766459
Chapman S, Ashack K, Dapprich DC
Cutis 2021 Jan;107(1):E10-E11. doi: 10.12788/cutis.0160. PMID: 33651868
Coscarart A, Martel J, Lee MP, Wang AR
J Cutan Pathol 2020 Mar;47(3):275-279. Epub 2019 Oct 20 doi: 10.1111/cup.13587. PMID: 31589773
Maarouf M, Alexander C, Shi VY
Dermatol Online J 2018 Jan 15;24(1) PMID: 29469765
Theodosiou G, Papageorgiou M, Vakirlis E, Mandekou-Lefaki I
Dermatol Ther 2016 Sep;29(5):338-340. Epub 2016 Jun 30 doi: 10.1111/dth.12372. PMID: 27357021

Prognosis

Guillen-Climent S, Porcar Saura S, Monteagudo C, Ramón Quiles MD
Actas Dermosifiliogr (Engl Ed) 2021 Feb;112(2):184-185. Epub 2020 Sep 28 doi: 10.1016/j.ad.2019.04.020. PMID: 33002453
Marsch AF
Am J Dermatopathol 2018 Sep;40(9):655-660. doi: 10.1097/DAD.0000000000001166. PMID: 29697423
Tong LX, Weinstock MJ, Drews R, Sheikine Y, Kim CC
Pediatr Dermatol 2015 May-Jun;32(3):e98-101. Epub 2015 Mar 5 doi: 10.1111/pde.12549. PMID: 25739384
Shah K, Kazlouskaya V, Lal K, Molina D, Elston DM
J Cutan Pathol 2014 Feb;41(2):108-12. Epub 2013 Nov 5 doi: 10.1111/cup.12247. PMID: 24138600
Giesecke LM, Reid CM, James CL, Huilgol SC
Australas J Dermatol 2003 Nov;44(4):267-9. doi: 10.1046/j.1440-0960.2003.00006.x. PMID: 14616493

Clinical prediction guides

Kuraitis D, Murina A
Cutis 2024 Jan;113(1):29-34. doi: 10.12788/cutis.0914. PMID: 38478947
Astudillo MG, Hoang MP, Nazarian RM, Foreman RK
Am J Dermatopathol 2021 May 1;43(5):349-355. doi: 10.1097/DAD.0000000000001776. PMID: 33395040
Marsch AF
Am J Dermatopathol 2018 Sep;40(9):655-660. doi: 10.1097/DAD.0000000000001166. PMID: 29697423
Kossard S, Thompson C, Duncan GM
Arch Dermatol 2004 Oct;140(10):1262-7. doi: 10.1001/archderm.140.10.1262. PMID: 15492191
Ragaz A, Ackerman AB
Am J Dermatopathol 1981 Spring;3(1):5-25. doi: 10.1097/00000372-198100310-00002. PMID: 7235199

Recent systematic reviews

Sanchez I, Ibraheim MK, Lee BA, Kraus CN, Elsensohn A
Am J Dermatopathol 2023 Dec 1;45(12):820-821. doi: 10.1097/DAD.0000000000002550. PMID: 37883982

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