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Megacolon

MedGen UID:
6285
Concept ID:
C0025160
Pathologic Function
Synonym: Megacolons
SNOMED CT: Megacolon (33995003); Dilatation of colon (33995003)
 
Monarch Initiative: MONDO:0001273

Definition

An abnormal dilation of the colon not due to obstruction. [from NCI]

Professional guidelines

PubMed

Iqbal T, DuPont HL
Curr Opin Gastroenterol 2021 Jan;37(1):66-75. doi: 10.1097/MOG.0000000000000693. PMID: 33105253
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
Kessmann J
Am Fam Physician 2006 Oct 15;74(8):1319-22. PMID: 17087425

Recent clinical studies

Etiology

Abad CLR, Safdar N
Gastroenterol Clin North Am 2021 Jun;50(2):323-340. doi: 10.1016/j.gtc.2021.02.010. PMID: 34024444
Liu D, Zeng L, Yan Z, Jia J, Gao J, Wei Y
Expert Rev Anti Infect Ther 2020 Oct;18(10):967-975. Epub 2020 Jun 16 doi: 10.1080/14787210.2020.1778464. PMID: 32520637
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
Saunders MD
Best Pract Res Clin Gastroenterol 2007;21(4):671-87. doi: 10.1016/j.bpg.2007.03.001. PMID: 17643908
Settle CD
Br J Hosp Med 1996 Oct 16-Nov 5;56(8):398-400. PMID: 8909713

Diagnosis

Eghbali E, Akhavi Milani A, Shirmohamadi M, Hosseinifard H
Radiography (Lond) 2021 May;27(2):716-720. Epub 2020 Nov 12 doi: 10.1016/j.radi.2020.10.019. PMID: 33189537
Iqbal T, DuPont HL
Curr Opin Gastroenterol 2021 Jan;37(1):66-75. doi: 10.1097/MOG.0000000000000693. PMID: 33105253
Wang XJ, Camilleri M
Dig Dis Sci 2019 Oct;64(10):2750-2756. Epub 2019 Apr 5 doi: 10.1007/s10620-019-05605-7. PMID: 30953226Free PMC Article
Autenrieth DM, Baumgart DC
Inflamm Bowel Dis 2012 Mar;18(3):584-91. doi: 10.1002/ibd.21847. PMID: 22009735
Thomford NR
Surg Annu 1980;12:341-50. PMID: 6996173

Therapy

Abad CLR, Safdar N
Gastroenterol Clin North Am 2021 Jun;50(2):323-340. doi: 10.1016/j.gtc.2021.02.010. PMID: 34024444
Iqbal T, DuPont HL
Curr Opin Gastroenterol 2021 Jan;37(1):66-75. doi: 10.1097/MOG.0000000000000693. PMID: 33105253
Mounsey A, Lacy Smith K, Reddy VC, Nickolich S
Am Fam Physician 2020 Feb 1;101(3):168-175. PMID: 32003951
Mullish BH, Williams HR
Clin Med (Lond) 2018 Jun;18(3):237-241. doi: 10.7861/clinmedicine.18-3-237. PMID: 29858434Free PMC Article
Teixeira AR, Nitz N, Guimaro MC, Gomes C, Santos-Buch CA
Postgrad Med J 2006 Dec;82(974):788-98. doi: 10.1136/pgmj.2006.047357. PMID: 17148699Free PMC Article

Prognosis

Gajendran M, Loganathan P, Jimenez G, Catinella AP, Ng N, Umapathy C, Ziade N, Hashash JG
Dis Mon 2019 Dec;65(12):100851. Epub 2019 Mar 2 doi: 10.1016/j.disamonth.2019.02.004. PMID: 30837080
Alcalá Hernández L, Reigadas Ramírez E, Bouza Santiago E
Med Clin (Barc) 2017 May 23;148(10):456-463. Epub 2017 Apr 8 doi: 10.1016/j.medcli.2017.01.033. PMID: 28396132
Teixeira AR, Nitz N, Guimaro MC, Gomes C, Santos-Buch CA
Postgrad Med J 2006 Dec;82(974):788-98. doi: 10.1136/pgmj.2006.047357. PMID: 17148699Free PMC Article
Sheth SG, LaMont JT
Lancet 1998 Feb 14;351(9101):509-13. doi: 10.1016/S0140-6736(97)10475-5. PMID: 9482465
Present DH
Med Clin North Am 1993 Sep;77(5):1129-48. doi: 10.1016/s0025-7125(16)30214-0. PMID: 8371619

Clinical prediction guides

Grossman RM, Sumner JP, Lopez DJ, Dornbusch JA, Singh A, Lux CN, Sample SJ, Liptak JM, Grimes JA, Upchurch DA, Blumenthal MS, Traverson M, Buote NJ, Marvel SJ, Steffey MA, Arai S, Little JP, Atilla A, Huck JL, Pitt KA
J Am Vet Med Assoc 2021 Nov 1;259(11):1292-1299. doi: 10.2460/javma.20.07.0418. PMID: 34727062
Gajendran M, Loganathan P, Jimenez G, Catinella AP, Ng N, Umapathy C, Ziade N, Hashash JG
Dis Mon 2019 Dec;65(12):100851. Epub 2019 Mar 2 doi: 10.1016/j.disamonth.2019.02.004. PMID: 30837080
Carod-Artal FJ
Clin Auton Res 2018 Feb;28(1):67-81. Epub 2017 Jul 20 doi: 10.1007/s10286-017-0452-4. PMID: 28730326
Antinori S, Galimberti L, Bianco R, Grande R, Galli M, Corbellino M
Eur J Intern Med 2017 Sep;43:6-15. Epub 2017 May 11 doi: 10.1016/j.ejim.2017.05.001. PMID: 28502864
Teixeira AR, Nitz N, Guimaro MC, Gomes C, Santos-Buch CA
Postgrad Med J 2006 Dec;82(974):788-98. doi: 10.1136/pgmj.2006.047357. PMID: 17148699Free PMC Article

Recent systematic reviews

Eghbali E, Akhavi Milani A, Shirmohamadi M, Hosseinifard H
Radiography (Lond) 2021 May;27(2):716-720. Epub 2020 Nov 12 doi: 10.1016/j.radi.2020.10.019. PMID: 33189537
Cuda T, Gunnarsson R, de Costa A
BMC Gastroenterol 2018 Jan 31;18(1):25. doi: 10.1186/s12876-018-0753-7. PMID: 29385992Free PMC Article
Moura FA, de Andrade KQ, Dos Santos JCF, Araújo ORP, Goulart MOF
Redox Biol 2015 Dec;6:617-639. Epub 2015 Oct 23 doi: 10.1016/j.redox.2015.10.006. PMID: 26520808Free PMC Article
Hofmann AD, Puri P
Pediatr Surg Int 2013 Sep;29(9):913-7. doi: 10.1007/s00383-013-3352-2. PMID: 23948812
Gladman MA, Scott SM, Lunniss PJ, Williams NS
Ann Surg 2005 Apr;241(4):562-74. doi: 10.1097/01.sla.0000157140.69695.d3. PMID: 15798457Free PMC Article

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