From HPO
Joint hemorrhage- MedGen UID:
- 5479
- •Concept ID:
- C0018924
- •
- Pathologic Function
Hemorrhage occurring within a joint.
Intracranial hemorrhage- MedGen UID:
- 101799
- •Concept ID:
- C0151699
- •
- Pathologic Function
Hemorrhage occurring within the skull.
Epistaxis- MedGen UID:
- 4996
- •Concept ID:
- C0014591
- •
- Pathologic Function
Epistaxis, or nosebleed, refers to a hemorrhage localized in the nose.
Gingival bleeding- MedGen UID:
- 42218
- •Concept ID:
- C0017565
- •
- Pathologic Function
Hemorrhage affecting the gingiva.
Abnormal bleeding- MedGen UID:
- 264316
- •Concept ID:
- C1458140
- •
- Pathologic Function
An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.
Persistent bleeding after trauma- MedGen UID:
- 375403
- •Concept ID:
- C1844374
- •
- Finding
Factor XIII, A subunit, deficiency of- MedGen UID:
- 442497
- •Concept ID:
- C2750514
- •
- Disease or Syndrome
Factor XIII deficiency is an autosomal recessive hematologic disorder characterized by increased bleeding and poor wound healing. Most cases of congenital factor XIII deficiency result from mutation in the A subunit (Kangsadalampai et al., 1999).
Ichinose et al. (1996, 2000) proposed a classification of factor XIII deficiency: XIIIA deficiency (formerly 'type II' F13 deficiency) and XIIIB deficiency (formerly 'type I' F13 deficiency), as well as a possible combined deficiency of the 2.
Abnormal umbilical stump bleeding- MedGen UID:
- 868740
- •Concept ID:
- C4023145
- •
- Anatomical Abnormality
Abnormal bleeding of the umbilical stump following separation of the cord at approximately 7-10 days after birth.
Reduced factor XIII activity- MedGen UID:
- 870254
- •Concept ID:
- C4024692
- •
- Finding
Decreased activity of coagulation factor XIII (also known as fibrin stabilizing factor). Activated Factor XIII cross-links fibrin polymers solidifying the clot.
Ecchymosis- MedGen UID:
- 8524
- •Concept ID:
- C0013491
- •
- Finding
A purpuric lesion that is larger than 1 cm in diameter.
Bruising susceptibility- MedGen UID:
- 140849
- •Concept ID:
- C0423798
- •
- Finding
An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.
Spontaneous hematomas- MedGen UID:
- 306397
- •Concept ID:
- C1697453
- •
- Disease or Syndrome
Spontaneous development of hematomas (hematoma) or bruises without significant trauma.
- Abnormality of blood and blood-forming tissues
- Abnormality of the cardiovascular system
- Abnormality of the integument