U.S. flag

An official website of the United States government

We are planning the future of MedGen. Fill out this survey or email us at medgen_help@ncbi.nlm.nih.gov to tell us how it can work better for you.
  • Quoted phrase not found.

Difficulty walking

MedGen UID:
86319
Concept ID:
C0311394
Finding
Synonyms: Ambulation Difficulties; Ambulation Difficulty; Ambulatory Difficulties; Ambulatory Difficulty; Difficulties, Ambulation; Difficulties, Ambulatory; Difficulty Ambulation; Difficulty Walking; Difficulty, Ambulation; Walking, Difficulty
SNOMED CT: Difficulty walking (719232003)

Definition

Any persistent problem with walking. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDifficulty walking

Professional guidelines

PubMed

Iff J, Carmichael C, McKee S, Sehinovych I, McNeill C, Tesi-Rocha C, Henricson E, Muntoni F, Kitchen H
Adv Ther 2024 Aug;41(8):3278-3298. Epub 2024 Jul 3 doi: 10.1007/s12325-024-02915-9. PMID: 38958840Free PMC Article
Wang CP, Syrkin-Nikolau M, Farnaes L, Shen D, Kanegaye M, Kuo DJ
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e358-e361. doi: 10.1097/MPH.0000000000002202. PMID: 34001791
Morgan JC, Ye X, Mellor JA, Golden KJ, Zamudio J, Chiodo LA, Bao Y, Xie T
J Neurol Sci 2021 Feb 15;421:117293. Epub 2020 Dec 25 doi: 10.1016/j.jns.2020.117293. PMID: 33385754

Recent clinical studies

Etiology

Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Mansfield A, Inness EL, Mcilroy WE
Handb Clin Neurol 2018;159:205-228. doi: 10.1016/B978-0-444-63916-5.00013-6. PMID: 30482315
Ikemoto T, Arai YC
Clin Interv Aging 2018;13:819-827. Epub 2018 Apr 30 doi: 10.2147/CIA.S148683. PMID: 29750024Free PMC Article
Fink JK
Exp Neurol 2003 Nov;184 Suppl 1:S106-10. doi: 10.1016/j.expneurol.2003.08.005. PMID: 14597333
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483

Diagnosis

Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Benson JC, Trejo-Lopez JA, Nassiri AM, Eschbacher K, Link MJ, Driscoll CL, Tiegs RD, Sfeir J, DeLone DR
AJNR Am J Neuroradiol 2022 Jun;43(6):817-822. Epub 2022 May 19 doi: 10.3174/ajnr.A7513. PMID: 35589138Free PMC Article
Badon HR, Pearlman RL, Brodell RT
J Fam Pract 2021 Jun;70(5):249-251. doi: 10.12788/jfp.0199. PMID: 34410917
Ikemoto T, Arai YC
Clin Interv Aging 2018;13:819-827. Epub 2018 Apr 30 doi: 10.2147/CIA.S148683. PMID: 29750024Free PMC Article
Fink JK
Exp Neurol 2003 Nov;184 Suppl 1:S106-10. doi: 10.1016/j.expneurol.2003.08.005. PMID: 14597333

Therapy

Chugh PV, Danford J, Farber A, Ayalon N, Verma A, Helm RH, Monahan KM, Kalish JA
Vasc Endovascular Surg 2024 Oct;58(7):752-756. Epub 2024 May 15 doi: 10.1177/15385744241251657. PMID: 38747057
Ilari S, Passacatini LC, Malafoglia V, Oppedisano F, Maiuolo J, Gliozzi M, Palma E, Tomino C, Fini M, Raffaeli W, Mollace V, Muscoli C
Pharmacol Res 2022 Dec;186:106547. Epub 2022 Nov 4 doi: 10.1016/j.phrs.2022.106547. PMID: 36336218
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Lund RM, Becker ML, Shapiro S, Allison T, Harris JG
BMC Pediatr 2019 Jul 6;19(1):228. doi: 10.1186/s12887-019-1605-5. PMID: 31279337Free PMC Article

Prognosis

Matsushima H, Kikuchi M, Shintani T
JAMA Oncol 2024 Jul 1;10(7):973-974. doi: 10.1001/jamaoncol.2024.0978. PMID: 38780956
Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ
JAMA Intern Med 2022 Nov 1;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062Free PMC Article
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Yadav GS, Marashi A
BMJ Case Rep 2019 May 10;12(5) doi: 10.1136/bcr-2018-228535. PMID: 31079041Free PMC Article
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483

Clinical prediction guides

Cao C, Yang L, Schmitz KH, Ligibel JA
J Clin Oncol 2024 Jul 1;42(19):2257-2270. Epub 2024 Apr 4 doi: 10.1200/JCO.23.02536. PMID: 38574313Free PMC Article
Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ
JAMA Intern Med 2022 Nov 1;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062Free PMC Article
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Yapıcıer Ö, Demir MK, Özdamarlar U, Kılıç D, Akakın A, Kılıç T
Childs Nerv Syst 2019 Jul;35(7):1251-1255. Epub 2019 Mar 12 doi: 10.1007/s00381-019-04113-3. PMID: 30859299
Sims RV, McGwin G Jr, Pulley LV, Roseman JM
J Aging Health 2001 Aug;13(3):430-8. doi: 10.1177/089826430101300306. PMID: 11813734

Recent systematic reviews

Abbas A, Hassan MA, Shaheen RS, Hussein A, Moawad MHED, Meshref M, Raslan AM
Neurol Sci 2024 Oct;45(10):4687-4698. Epub 2024 Jun 6 doi: 10.1007/s10072-024-07617-2. PMID: 38842771Free PMC Article
Allahyari F, Molaee H, Hosseini Nejad J
Z Naturforsch C J Biosci 2023 Jan 27;78(1-2):1-8. Epub 2022 Sep 12 doi: 10.1515/znc-2022-0092. PMID: 36087300
Ilari S, Passacatini LC, Malafoglia V, Oppedisano F, Maiuolo J, Gliozzi M, Palma E, Tomino C, Fini M, Raffaeli W, Mollace V, Muscoli C
Pharmacol Res 2022 Dec;186:106547. Epub 2022 Nov 4 doi: 10.1016/j.phrs.2022.106547. PMID: 36336218
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Gewandter JS, Burke L, Cavaletti G, Dworkin RH, Gibbons C, Gover TD, Herrmann DN, Mcarthur JC, McDermott MP, Rappaport BA, Reeve BB, Russell JW, Smith AG, Smith SM, Turk DC, Vinik AI, Freeman R
Muscle Nerve 2017 Mar;55(3):366-372. Epub 2016 Dec 23 doi: 10.1002/mus.25264. PMID: 27447116Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    External link. Please review our privacy policy.