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Motor Manifestations

MedGen UID:
233196
Concept ID:
C1334804
Sign or Symptom

Definition

The presence of an alteration in the ability to move one''s body or any body parts in accordance with one''s intent. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMotor Manifestations

Professional guidelines

PubMed

Varesi A, Campagnoli LIM, Fahmideh F, Pierella E, Romeo M, Ricevuti G, Nicoletta M, Chirumbolo S, Pascale A
Int J Mol Sci 2022 Oct 14;23(20) doi: 10.3390/ijms232012289. PMID: 36293176Free PMC Article
Jankovic J, Tan EK
J Neurol Neurosurg Psychiatry 2020 Aug;91(8):795-808. Epub 2020 Jun 23 doi: 10.1136/jnnp-2019-322338. PMID: 32576618
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G
Mov Disord 2015 Oct;30(12):1591-601. doi: 10.1002/mds.26424. PMID: 26474316

Recent clinical studies

Etiology

Tandon R, Nasrallah H, Akbarian S, Carpenter WT Jr, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, Yassin W, Keshavan M
Schizophr Res 2024 Feb;264:1-28. Epub 2023 Dec 12 doi: 10.1016/j.schres.2023.11.015. PMID: 38086109
Calabresi P, Di Lazzaro G, Marino G, Campanelli F, Ghiglieri V
Brain 2023 Sep 1;146(9):3587-3597. doi: 10.1093/brain/awad150. PMID: 37183455Free PMC Article
Bellomo G, De Luca CMG, Paoletti FP, Gaetani L, Moda F, Parnetti L
Neurology 2022 Aug 2;99(5):195-205. Epub 2022 Jun 3 doi: 10.1212/WNL.0000000000200878. PMID: 35914941
Fereshtehnejad SM, Zeighami Y, Dagher A, Postuma RB
Brain 2017 Jul 1;140(7):1959-1976. doi: 10.1093/brain/awx118. PMID: 28549077
Rios Romenets S, Anang J, Fereshtehnejad SM, Pelletier A, Postuma R
Complement Ther Med 2015 Apr;23(2):175-84. Epub 2015 Feb 9 doi: 10.1016/j.ctim.2015.01.015. PMID: 25847555

Diagnosis

Galiero R, Caturano A, Vetrano E, Beccia D, Brin C, Alfano M, Di Salvo J, Epifani R, Piacevole A, Tagliaferri G, Rocco M, Iadicicco I, Docimo G, Rinaldi L, Sardu C, Salvatore T, Marfella R, Sasso FC
Int J Mol Sci 2023 Feb 10;24(4) doi: 10.3390/ijms24043554. PMID: 36834971Free PMC Article
Jankovic J, Tan EK
J Neurol Neurosurg Psychiatry 2020 Aug;91(8):795-808. Epub 2020 Jun 23 doi: 10.1136/jnnp-2019-322338. PMID: 32576618
Masrori P, Van Damme P
Eur J Neurol 2020 Oct;27(10):1918-1929. Epub 2020 Jul 7 doi: 10.1111/ene.14393. PMID: 32526057Free PMC Article
Reich SG, Savitt JM
Med Clin North Am 2019 Mar;103(2):337-350. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.014. PMID: 30704685
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G
Mov Disord 2015 Oct;30(12):1591-601. doi: 10.1002/mds.26424. PMID: 26474316

Therapy

Joza S, Hu MT, Jung KY, Kunz D, Stefani A, Dušek P, Terzaghi M, Arnaldi D, Videnovic A, Schiess MC, Hermann W, Lee JY, Ferini-Strambi L, Lewis SJG, Leclair-Visonneau L, Oertel WH, Antelmi E, Sixel-Döring F, Cochen De Cock V, Liguori C, Liu J, Provini F, Puligheddu M, Nicoletti A, Bassetti CLA, Bušková J, Dauvilliers Y, Ferri R, Montplaisir JY, Lawton M, Kim HJ, Bes F, Högl B, Šonka K, Fiamingo G, Mattioli P, Lavadia ML, Suescun J, Woo KA, Marelli S, Martens KE, Janzen A, Plazzi G, Mollenhauer B, Fernandes M, Li Y, Cortelli P, Figorilli M, Cicero CE, Schaefer C, Guiraud L, Lanza G, Gagnon JF, Sunwoo JS, Ibrahim A, Girtler N, Trenkwalder C, Baldelli L, Pelletier A, Postuma RB; International REM Sleep Behavior Disorder Study Group
Brain 2023 Aug 1;146(8):3258-3272. doi: 10.1093/brain/awad072. PMID: 36881989
Jankovic J, Tan EK
J Neurol Neurosurg Psychiatry 2020 Aug;91(8):795-808. Epub 2020 Jun 23 doi: 10.1136/jnnp-2019-322338. PMID: 32576618
Nakamori M, Junn E, Mochizuki H, Mouradian MM
Neurotherapeutics 2019 Apr;16(2):287-298. doi: 10.1007/s13311-019-00714-7. PMID: 30756362Free PMC Article
Reich SG, Savitt JM
Med Clin North Am 2019 Mar;103(2):337-350. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.014. PMID: 30704685
Rios Romenets S, Anang J, Fereshtehnejad SM, Pelletier A, Postuma R
Complement Ther Med 2015 Apr;23(2):175-84. Epub 2015 Feb 9 doi: 10.1016/j.ctim.2015.01.015. PMID: 25847555

Prognosis

Tandon R, Nasrallah H, Akbarian S, Carpenter WT Jr, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, Yassin W, Keshavan M
Schizophr Res 2024 Feb;264:1-28. Epub 2023 Dec 12 doi: 10.1016/j.schres.2023.11.015. PMID: 38086109
Calabresi P, Di Lazzaro G, Marino G, Campanelli F, Ghiglieri V
Brain 2023 Sep 1;146(9):3587-3597. doi: 10.1093/brain/awad150. PMID: 37183455Free PMC Article
Joza S, Hu MT, Jung KY, Kunz D, Stefani A, Dušek P, Terzaghi M, Arnaldi D, Videnovic A, Schiess MC, Hermann W, Lee JY, Ferini-Strambi L, Lewis SJG, Leclair-Visonneau L, Oertel WH, Antelmi E, Sixel-Döring F, Cochen De Cock V, Liguori C, Liu J, Provini F, Puligheddu M, Nicoletti A, Bassetti CLA, Bušková J, Dauvilliers Y, Ferri R, Montplaisir JY, Lawton M, Kim HJ, Bes F, Högl B, Šonka K, Fiamingo G, Mattioli P, Lavadia ML, Suescun J, Woo KA, Marelli S, Martens KE, Janzen A, Plazzi G, Mollenhauer B, Fernandes M, Li Y, Cortelli P, Figorilli M, Cicero CE, Schaefer C, Guiraud L, Lanza G, Gagnon JF, Sunwoo JS, Ibrahim A, Girtler N, Trenkwalder C, Baldelli L, Pelletier A, Postuma RB; International REM Sleep Behavior Disorder Study Group
Brain 2023 Aug 1;146(8):3258-3272. doi: 10.1093/brain/awad072. PMID: 36881989
Jankovic J, Tan EK
J Neurol Neurosurg Psychiatry 2020 Aug;91(8):795-808. Epub 2020 Jun 23 doi: 10.1136/jnnp-2019-322338. PMID: 32576618
Fereshtehnejad SM, Zeighami Y, Dagher A, Postuma RB
Brain 2017 Jul 1;140(7):1959-1976. doi: 10.1093/brain/awx118. PMID: 28549077

Clinical prediction guides

Joza S, Hu MT, Jung KY, Kunz D, Stefani A, Dušek P, Terzaghi M, Arnaldi D, Videnovic A, Schiess MC, Hermann W, Lee JY, Ferini-Strambi L, Lewis SJG, Leclair-Visonneau L, Oertel WH, Antelmi E, Sixel-Döring F, Cochen De Cock V, Liguori C, Liu J, Provini F, Puligheddu M, Nicoletti A, Bassetti CLA, Bušková J, Dauvilliers Y, Ferri R, Montplaisir JY, Lawton M, Kim HJ, Bes F, Högl B, Šonka K, Fiamingo G, Mattioli P, Lavadia ML, Suescun J, Woo KA, Marelli S, Martens KE, Janzen A, Plazzi G, Mollenhauer B, Fernandes M, Li Y, Cortelli P, Figorilli M, Cicero CE, Schaefer C, Guiraud L, Lanza G, Gagnon JF, Sunwoo JS, Ibrahim A, Girtler N, Trenkwalder C, Baldelli L, Pelletier A, Postuma RB; International REM Sleep Behavior Disorder Study Group
Brain 2023 Aug 1;146(8):3258-3272. doi: 10.1093/brain/awad072. PMID: 36881989
Youn J, Todisco M, Zappia M, Pacchetti C, Fasano A
J Neurol Sci 2022 Feb 15;433:120019. Epub 2021 Oct 1 doi: 10.1016/j.jns.2021.120019. PMID: 34674853
Wang HP, Wong LC, Hsu CJ, Hu SC, Chu YJ, Lee WT
J Formos Med Assoc 2022 Apr;121(4):736-748. Epub 2021 Sep 22 doi: 10.1016/j.jfma.2021.09.003. PMID: 34561118
Fereshtehnejad SM, Zeighami Y, Dagher A, Postuma RB
Brain 2017 Jul 1;140(7):1959-1976. doi: 10.1093/brain/awx118. PMID: 28549077
Rios Romenets S, Anang J, Fereshtehnejad SM, Pelletier A, Postuma R
Complement Ther Med 2015 Apr;23(2):175-84. Epub 2015 Feb 9 doi: 10.1016/j.ctim.2015.01.015. PMID: 25847555

Recent systematic reviews

Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L
J Clin Neurophysiol 2023 Sep 1;40(6):507-515. Epub 2023 Mar 15 doi: 10.1097/WNP.0000000000000975. PMID: 36930208
Ramanzini LG, Camargo LFM, Silveira JOF, Bochi GV
Neurol Sci 2022 Dec;43(12):6707-6717. Epub 2022 Aug 30 doi: 10.1007/s10072-022-06363-7. PMID: 36040559
Zhou DJ, Pavuluri S, Snehal I, Schmidt CM, Situ-Kcomt M, Taraschenko O
Epilepsy Behav 2022 Jun;131(Pt A):108693. Epub 2022 Apr 25 doi: 10.1016/j.yebeh.2022.108693. PMID: 35483204Free PMC Article
Elfil M, Bahbah EI, Attia MM, Eldokmak M, Koo BB
Mov Disord 2021 Mar;36(3):570-580. Epub 2020 Dec 9 doi: 10.1002/mds.28412. PMID: 33296545
Takamiya A, Seki M, Kudo S, Yoshizaki T, Nakahara J, Mimura M, Kishimoto T
Mov Disord 2021 Jan;36(1):50-58. Epub 2020 Oct 14 doi: 10.1002/mds.28335. PMID: 33280168

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