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Increased circulating IgE concentration

MedGen UID:
116018
Concept ID:
C0236175
Finding
Synonyms: Ige, elevated level of; Increased IgE level
 
HPO: HP:0003212
OMIM®: 147050

Definition

An abnormally increased overall level of immunoglobulin E in blood. [from HPO]

Conditions with this feature

Professional guidelines

PubMed

Bekhti A, Schaaps JP, Capron M, Dessaint JP, Santoro F, Capron A
Br Med J 1977 Oct 22;2(6094):1047-51. doi: 10.1136/bmj.2.6094.1047. PMID: 922416Free PMC Article

Recent clinical studies

Etiology

Li Z, Ma A, Miller I, Starnes R, Talkington A, Stone CA, Phillips EJ, Choudhary SK, Commins SP, Lai SK
J Control Release 2024 Feb;366:342-348. Epub 2024 Jan 8 doi: 10.1016/j.jconrel.2024.01.003. PMID: 38182056Free PMC Article
Phipatanakul W, Mauger DT, Guilbert TW, Bacharier LB, Durrani S, Jackson DJ, Martinez FD, Fitzpatrick AM, Cunningham A, Kunselman S, Wheatley LM, Bauer C, Davis CM, Geng B, Kloepfer KM, Lapin C, Liu AH, Pongracic JA, Teach SJ, Chmiel J, Gaffin JM, Greenhawt M, Gupta MR, Lai PS, Lemanske RF, Morgan WJ, Sheehan WJ, Stokes J, Thorne PS, Oettgen HC, Israel E; PARK Study Team
Contemp Clin Trials 2021 Jan;100:106228. Epub 2020 Nov 24 doi: 10.1016/j.cct.2020.106228. PMID: 33242697Free PMC Article
Cristi F, Perez-Mateluna G, Vera-Kellet C, Silva-Valenzuela S, Iturriaga C, Hoyos-Bachiloglu R, Navarrete-Dechent C, Cifuentes L, Camargo CA Jr, Kalergis AM, Borzutzky A
Exp Dermatol 2019 Mar;28(3):308-311. Epub 2019 Feb 12 doi: 10.1111/exd.13873. PMID: 30624829
Van Hemelrijck M, Karagiannis SN, Rohrmann S
Cancer Immunol Immunother 2017 Dec;66(12):1557-1562. Epub 2017 Aug 9 doi: 10.1007/s00262-017-2048-1. PMID: 28795218Free PMC Article
Michavila Gomez AV, Belver Gonzalez MT, Alvarez NC, Giner Muñoz MT, Hernando Sastre V, Porto Arceo JA, Induráin BV; Drug allergy Work Group of the Spanish Society of Paediatric Allergy, Immunology (SEICAP)
Allergol Immunopathol (Madr) 2015 Mar-Apr;43(2):203-14. Epub 2013 Nov 11 doi: 10.1016/j.aller.2013.07.012. PMID: 24231150

Diagnosis

Li Z, Ma A, Miller I, Starnes R, Talkington A, Stone CA, Phillips EJ, Choudhary SK, Commins SP, Lai SK
J Control Release 2024 Feb;366:342-348. Epub 2024 Jan 8 doi: 10.1016/j.jconrel.2024.01.003. PMID: 38182056Free PMC Article
Wei B, Sheng Li C
J Int Med Res 2018 Sep;46(9):3890-3902. Epub 2018 Jun 27 doi: 10.1177/0300060518781642. PMID: 29950127Free PMC Article
Van Hemelrijck M, Karagiannis SN, Rohrmann S
Cancer Immunol Immunother 2017 Dec;66(12):1557-1562. Epub 2017 Aug 9 doi: 10.1007/s00262-017-2048-1. PMID: 28795218Free PMC Article
Michavila Gomez AV, Belver Gonzalez MT, Alvarez NC, Giner Muñoz MT, Hernando Sastre V, Porto Arceo JA, Induráin BV; Drug allergy Work Group of the Spanish Society of Paediatric Allergy, Immunology (SEICAP)
Allergol Immunopathol (Madr) 2015 Mar-Apr;43(2):203-14. Epub 2013 Nov 11 doi: 10.1016/j.aller.2013.07.012. PMID: 24231150
Duncan JS
Epilepsia 2005;46 Suppl 9:108-11. doi: 10.1111/j.1528-1167.2005.00321.x. PMID: 16302883

Therapy

Roach KA, Anderson SE, Waggy C, Aldinger J, Stefaniak AB, Roberts JR
J Immunotoxicol 2024 Dec;21(1):2414979. Epub 2024 Dec 4 doi: 10.1080/1547691X.2024.2414979. PMID: 39632339Free PMC Article
Wang G, Li M, Zheng J, Zhan J, Zheng H, Li R, Wei X
Int Immunopharmacol 2022 Mar;104:108515. Epub 2022 Jan 7 doi: 10.1016/j.intimp.2021.108515. PMID: 35008009
Phipatanakul W, Mauger DT, Guilbert TW, Bacharier LB, Durrani S, Jackson DJ, Martinez FD, Fitzpatrick AM, Cunningham A, Kunselman S, Wheatley LM, Bauer C, Davis CM, Geng B, Kloepfer KM, Lapin C, Liu AH, Pongracic JA, Teach SJ, Chmiel J, Gaffin JM, Greenhawt M, Gupta MR, Lai PS, Lemanske RF, Morgan WJ, Sheehan WJ, Stokes J, Thorne PS, Oettgen HC, Israel E; PARK Study Team
Contemp Clin Trials 2021 Jan;100:106228. Epub 2020 Nov 24 doi: 10.1016/j.cct.2020.106228. PMID: 33242697Free PMC Article
Akdis M, Akdis CA
J Allergy Clin Immunol 2007 Apr;119(4):780-91. Epub 2007 Feb 26 doi: 10.1016/j.jaci.2007.01.022. PMID: 17321578
Naus CW, van Dam GJ, Kremsner PG, Krijger FW, Deelder AM
Clin Infect Dis 1998 May;26(5):1142-7. doi: 10.1086/520310. PMID: 9597243

Prognosis

Packi K, Matysiak J, Klimczak S, Matuszewska E, Bręborowicz A, Pietkiewicz D, Matysiak J
Int J Environ Res Public Health 2022 Jun 27;19(13) doi: 10.3390/ijerph19137877. PMID: 35805534Free PMC Article
Wang G, Li M, Zheng J, Zhan J, Zheng H, Li R, Wei X
Int Immunopharmacol 2022 Mar;104:108515. Epub 2022 Jan 7 doi: 10.1016/j.intimp.2021.108515. PMID: 35008009
Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA
J Allergy Clin Immunol 2015 Jul;136(1):69-80. Epub 2015 Mar 11 doi: 10.1016/j.jaci.2015.01.025. PMID: 25769910Free PMC Article
Possin ME, Morgan S, DaSilva DF, Tisler C, Pappas TE, Roberg KA, Anderson E, Evans MD, Gangnon R, Lemanske RF, Gern JE
Pediatr Allergy Immunol 2010 Sep;21(6):990-6. Epub 2010 Apr 27 doi: 10.1111/j.1399-3038.2010.01041.x. PMID: 20444149Free PMC Article
Ceyhan BB, Sungur M, Celikel T, Ozgün SS
J Asthma 1995;32(6):419-27. doi: 10.3109/02770909409077753. PMID: 7592245

Clinical prediction guides

Bozorgmehr T, Boutin RCT, Woodward SE, Donald K, Chow JM, Buck RH, Finlay BB
J Immunol Res 2023;2023:9603576. Epub 2023 Jul 29 doi: 10.1155/2023/9603576. PMID: 37545544Free PMC Article
Van Hemelrijck M, Karagiannis SN, Rohrmann S
Cancer Immunol Immunother 2017 Dec;66(12):1557-1562. Epub 2017 Aug 9 doi: 10.1007/s00262-017-2048-1. PMID: 28795218Free PMC Article
Sanjuan MA, Sagar D, Kolbeck R
J Allergy Clin Immunol 2016 Jun;137(6):1651-1661. Epub 2016 Apr 27 doi: 10.1016/j.jaci.2016.04.007. PMID: 27264000
Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA
J Allergy Clin Immunol 2015 Jul;136(1):69-80. Epub 2015 Mar 11 doi: 10.1016/j.jaci.2015.01.025. PMID: 25769910Free PMC Article
Michavila Gomez AV, Belver Gonzalez MT, Alvarez NC, Giner Muñoz MT, Hernando Sastre V, Porto Arceo JA, Induráin BV; Drug allergy Work Group of the Spanish Society of Paediatric Allergy, Immunology (SEICAP)
Allergol Immunopathol (Madr) 2015 Mar-Apr;43(2):203-14. Epub 2013 Nov 11 doi: 10.1016/j.aller.2013.07.012. PMID: 24231150

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