NLR Proteins
Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.644.360.539
MeSH Unique ID: D000070576
Entry Terms:
- Proteins, NLR
- Nucleotide-Binding Domain Leucine-Rich Repeat Protein
- Nucleotide Binding Domain Leucine Rich Repeat Protein
- Nucleotide-binding Domain Leucine-rich Repeat Proteins
- Nucleotide binding Domain Leucine rich Repeat Proteins
- NLR Protein
- Protein, NLR
- NOD-like Receptor
- NOD like Receptor
- Receptor, NOD-like
- NOD-like Receptors
- NOD like Receptors
- Receptors, NOD-like
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