Nod1 Signaling Adaptor Protein
A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Year introduced: 2007
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Tree Number(s): D12.644.360.024.131.249, D12.644.360.024.313.249, D12.644.360.075.358.249, D12.644.360.539.500.249, D12.776.157.057.006.249, D12.776.157.057.078.249, D12.776.476.024.139.249, D12.776.476.024.391.249, D12.776.476.075.358.249
MeSH Unique ID: D053474
Entry Terms:
- CARD4 Protein
- Caspase Recruitment Domain Protein 4
- Nucleotide Oligomerization Domain 1 Protein
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