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Characterization of global loss of imprinting in overgrowth syndrome induced by assisted reproduction

(Submitter supplied) Embryos generated with the use of assisted reproductive technologies (ART) can develop overgrowth syndromes. In ruminants, the condition is referred to as large offspring syndrome (LOS) and exhibits variable phenotypic abnormalities including overgrowth, enlarged tongue, and abdominal wall defects. These characteristics recapitulate those observed in the human loss-of-imprinting (LOI) overgrowth syndrome Beckwith-Wiedemann (BWS). more...
Organism:
Bos indicus x Bos taurus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21383
32 Samples
Download data: TXT
Series
Accession:
GSE63509
ID:
200063509

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