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Full record GDS3812

Krüppel-like zinc finger transcription factor Gli-similar 3 knockout effect on embryonic pancreas

Analysis of pancreas from E15.5 embryos deficient in transcription factor Gli-similar 3 (Glis3). The Glis3zf/zf mutant pancreas shows a dramatic loss of β and δ cells, contrasting a smaller relative loss of α, PP, and ɛ cells. Results provide insight into the role of Glis3 in pancreas.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE18172
7 Samples
Download data: CEL

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