GEO DataSets

(Submitter supplied) The brown anole lizard, Anolis sagrei, is an emerging squamate model for developmental and functional genetic studies. To develop additional tools and resources for mechanistic studies of signaling pathways and cellular processes in A. sagrei, we established an in vitro system. Using this approach, we studied Hedgehog (Hh) signaling, one of the key developmental signaling pathways, which has evolved across the metazoa. more...

Organism:

Anolis sagrei; Mus musculus

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL19057 GPL26286

29 Samples

Download data: CSV, VCF, XLSX

(Submitter supplied) The basic plan of the retina is conserved across vertebrates, yet species differ profoundly in their visual needs (Baden et al., 2020). One might expect that retinal cell types evolved to accommodate these varied needs, but this has not been systematically studied. Here, we generated and integrated single-cell transcriptomic atlases of the retina from 17 species: humans, two non-human primates, four rodents, three ungulates, opossum, ferret, tree shrew, a teleost fish, a bird, a reptile and a lamprey. more...

Organism:

Anolis sagrei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33576

6 Samples

Download data: CSV

(Submitter supplied) For the purpose of facilitating gene annotation, a transcriptome profile of the developing anole eye was used to identify coding and non-coding regions in the Anolis genome. RNA datasets were generated by collecting samples from three subregions of the anole posterior globe (central, temporal, and nasal) which was comprised of nerual retina, retinal pigmented epithelium, choriod, and scleral tissues. more...

Organism:

Anolis sagrei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26286

15 Samples

Download data: TXT

(Submitter supplied) Lung function is closely coupled to its structural anatomy, which varies greatly across vertebrates. Although architecturally simple, a complex pattern of airflow is thought to be achieved in the lizard lung due to its cavernous central lumen and honeycomb-shaped wall. We find that the wall of the lizard lung is generated from an initially smooth epithelial sheet, which is pushed through holes in a hexagonal smooth muscle meshwork by forces from fluid pressure, similar to a stress ball. more...

Organism:

Anolis sagrei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29974

2 Samples

Download data: H5

(Submitter supplied) The goal of this study is to identify genetic network changes that accompany shifts in limb identity.

Organism:

Anolis sagrei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26286

10 Samples

Download data: TXT