GEO DataSets

(Submitter supplied) To reveal the correlation between epigenomic diversity and genomic SNVs, we first identified SNPs between T4 with other eleven Trichinella species. In total, we obtained 5,395,250 common SNVs across the twelve Trichinella species.

Organism:

Trichinella nelsoni; Trichinella pseudospiralis; Trichinella murrelli; Trichinella britovi; Trichinella papuae; Trichinella zimbabwensis; Trichinella patagoniensis; Trichinella spiralis; Trichinella nativa; Trichinella sp. T6; Trichinella sp. T8; Trichinella sp. T9

Type:

Other

12 related Platforms

12 Samples

Download data: TXT

(Submitter supplied) As DNA methylation can modulate gene expression, we then focused our analysis on changes of methylation at the host taxonomic level, that is between encapsulated and non-encapsulated clade, and within non-encapsulated clade, to reveal epigenetic regulation on transcriptomes from Ad and ML stages. By comparing DNA methylation patterns between different host classes of species, we found a fraction of parasitism-related genes under epigenetic regulation, such as G-protein-coupled receptor, DNaseII and ligand-gated chloride channel.

Organism:

Trichinella britovi; Trichinella murrelli; Trichinella papuae; Trichinella zimbabwensis; Trichinella patagoniensis; Trichinella sp. T8; Trichinella sp. T9; Trichinella sp. T6; Trichinella spiralis; Trichinella nativa; Trichinella nelsoni; Trichinella pseudospiralis

Type:

Expression profiling by high throughput sequencing

12 related Platforms

36 Samples

Download data: TXT

(Submitter supplied) As the most studied type of epigenetic modifications found in many taxa, DNA methylation has been confirmed to play a crucial role in transposon silencing, transcriptional regulation and thus phenotypic variation, as well as rapid adaption to changing environments. To fully understand the methylome variation in Trichinella, here, we report 12 single-base resolution methylomes of three life stages using WGBS. more...

Organism:

Trichinella sp. T6; Trichinella spiralis; Trichinella nativa; Trichinella zimbabwensis; Trichinella nelsoni; Trichinella pseudospiralis; Trichinella britovi; Trichinella murrelli; Trichinella patagoniensis; Trichinella sp. T8; Trichinella sp. T9; Trichinella papuae

Type:

Methylation profiling by high throughput sequencing

12 related Platforms

36 Samples

Download data: TXT

(Submitter supplied) Genome assemblies can form the basis of comparative analyses fostering insight into the evolutionary genetics. Genome evolution influences a parasite’s pathogenicity, host–pathogen interactions, environmental constraints and invasion biology. Comparative genomics and epigenomics analyses will provide deep understanding of parasitism biology for future diagnosis and prevention of trchinellosis. We provide a near-complete new T.p reference genome using SMRT technology, first time confirmed and characterized T.p DNA methylome, enabling full annotation. more...

Organism:

Trichinella pseudospiralis

Type:

Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:

GPL24891

6 Samples

Download data: FA, GFF, TXT