GEO DataSets

(Submitter supplied) The cerebral cortex plays an important role in cognitive function and specialized perception in mammals and its development requires highly specific spatio-temporal control of gene expression. The study identified stage- and region-specific markers throughout cerebral corticogenesis at various important stages of cerebral cortex development; embryonic day (E) 15.5, E17.5, postnatal day (P) 1.5 and 4-6 months old.

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platforms:

GPL11 GPL1349

12 Samples

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(Submitter supplied) This series represents the Cancer Genome Anatomy Project SAGE library collection. Libraries contained herein were either produced through CGAP funding, or donated to CGAP. The Cancer Genome Anatomy Project (CGAP: http://cgap.nci.nih.gov) is an interdisciplinary program established and administered by the National Cancer Institute (NCI: http://www.nci.nih.gov) to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

34 Samples

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(Submitter supplied) Recent improvements in the development of methods for isolating functionally validated populations of nearly pure (>20%) murine hematopoietic stem cells (HSCs) have made it possible to analyze the molecular basis of the properties of these cells with increased precision. One intriguing feature of HSCs is the change they undergo in many of their key properties during development a change that affects the control of their self-renewal, cycling status, differentiated progeny output and steel factor sensitivity. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

2 Samples

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(Submitter supplied) Background: The goal of this study was to determine the transcriptional consequences of norepinephrine transporter (NET) gene deletion in noradrenergic neuron differentiation. The norepinephrine transporter (NET) is the target of powerful mind-altering substances, such as tricyclic antidepressants and the drug of abuse, cocaine. NET function in adult noradrenergic neurons of the peripheral and central nervous systems is that of a scavenger that internalizes norepinephrine from the synaptic cleft. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

2 Samples

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(Submitter supplied) Using a TCR transgenic transplantation model a series of differently modulated bmDC (IL10, TGFb and VD3 treated, +/-LPS) were established that could mediate tolerance following adaptive transfer. These modified cells, in contrast to untreated 'immature' bmDC retained their capacity to tolerise following exposure to LPS. The unmodified, non-tolerogenic, LPS-treated cells provided a comparator population to facilitate investigation into molecular expression patterns that correlate with functional phenotype. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Mammalian Organogenesis - Regulation by Gene Expression Networks (MORGEN) Project Keywords: LongSAGE

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

14 Samples

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(Submitter supplied) This study aims to identify all genes expressed in primary mouse megakaryocytes Keywords: Megakaryocyte, SAGE, transcriptome analysis

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Mouse Atlas of Gene Expression Project A Quantitative and Comprehensive Atlas of Gene Expression in Mouse Development. Also available at CGAP: http://cgap.nci.nih.gov/ Keywords: LongSAGE, SAGE

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platforms:

GPL11 GPL1349

203 Samples

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(Submitter supplied) Cells were isolated from mouse embryonic neural crest stem cells at culture day 2 (NCSC), from day 7 in vitro differentiated progeny (NCP) and day 2 epidermal neural crest stem cells from bulge explants of adult whisker follicles (EPI-NCSC). Keywords: LongSAGE

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

3 Samples

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(Submitter supplied) Undifferentiated mammosphere RNA. Samples contain RNA extracted from the cells of mouse mammospheres. Mammosphere are believed to be comprised of stem/progenitor cells (GSM88038). Differentiated mammosphere RNA. RNA extracted from the cells of mouse mammospheres induced to differentiate over a 6-day period. Mammosphere are believed to be comprised of stem/progenitor cells (GSM88039). Keywords: mammosphere differentiation

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

2 Samples

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(Submitter supplied) LongSAGE library was constructed by standard methods with several modifications. Additional amplification step was not performed. Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) After 10-12 days in culture as neurospheres, the cells were cultured and plated on 5ug/ml poly-L-ornithine (1 hr RT, dry) and 10ug/ml laminin (O/N 4degC, dry) in stem cell differentiation medium. The cells were harvested 2 days later. Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Putative neural stem cells were derived from E12-E14 stiatal tissue and that was cultured for 10-12 dy s in neural stem cell media supplemented with bFGF Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Mouse R1 ES cell SAGE library Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Embryoid Bodies from Mouse R1 ES - 9 day Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) Owing to its increased tag length, LongSAGE tags are expected to be more reliable in direct assignment to genome sequences. Therefore, we evaluated the use of LongSAGE data in genome annotation by using our LongSAGE dataset of 202 015 tags (consisting of 41 718 unique tags), experimentally generated from mouse embryonic tail libraries. RESULTS: A fraction of LongSAGE tags could not be unambiguously assigned to its gene, due to the presence of widely conserved sequences downstream of particular CATG anchor sites. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

1 Sample

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(Submitter supplied) IL-10-Conditioned Dendritic Cells, Decommissioned for Recruitment of Adaptive Immunity, Elicit Innate Inflammatory Gene Products in Response to Danger Signals Dendritic cells (DCs) are the professional APCs of the immune system, enabling T cells to perceive and respond appropriately to potentially dangerous microbes, while also being able to maintain T cell tolerance toward self. In part, such tolerance can be determined by IL-10 released from certain types of regulatory T cells. more...

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platforms:

GPL11 GPL1349

26 Samples

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(Submitter supplied) This series represents the Cancer Genome Anatomy Project SAGE library collection. Libraries contained herein were either produced through CGAP funding, or donated to CGAP. The Cancer Genome Anatomy Project (CGAP: http://cgap.nci.nih.gov) is an interdisciplinary program established and administered by the National Cancer Institute (NCI: http://www.nci.nih.gov) to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell. more...

Organism:

Mus musculus; Homo sapiens

Type:

Expression profiling by SAGE

4 related Platforms

765 Samples

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