GPL13717[RGSE] - GEO DataSets

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Items: 3

Select item 2000380821.

Profiling epididymal white adipose tissue (eWAT) from obese db/db and lean control db/+ mice

(Submitter supplied) This program addresses the gene signature associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in adipose tissue of the db/db mice compared to the control db/+ mice?

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL13717
6 Samples

Download data: TXT

Series

Accession:: GSE38082

ID:: 200038082

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000315592.

Various mice and rat tissues subjected to various treatments

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Rattus norvegicus

Type:: Expression profiling by array

9 related Platforms
115 Samples

Download data: CEL

Series

Accession:: GSE31559

ID:: 200031559

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000312223.

Novel Transcriptome Profiling Analyses Demonstrate that Selective PPARg Modulators Display Attenuated and Selective Gene Regulatory Activity in Comparison with PPARg Full Agonists

(Submitter supplied) We conducted extensive transcriptome profiling studies to characterize 70 SPPARgMs and seven PPARg full agonists in 3T3-L1 adipocytes, and a subset of these ligands in adipose tissue of diabetic db/db mice. In both cases, the SPPARgMs generated attenuated gene regulatory responses, and their gene expression signatures were more enriched in metabolic pathways that are likely to mediate anti-diabetic efficacy than those of PPARg full agonists. more...