GPL13758[RGSE] - GEO DataSets

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Items: 2

Select item 2000302611.

Mature and aged Male and female rabbit heart gene expression in global ischemia and cardioplegia

(Submitter supplied) Background: Demographic studies have shown that the mean age of patients requiring coronary artery bypass surgery (CABG) is 68 years with approximately 44% of these patients being female . In recent studies, women have been shown to have a significantly greater operative risk as compared to men and that women have worse outcomes after cardiac surgery. Recently we have shown that cardioprotection afforded by cardioplegia is modulated by RNA and protein dependent mechanisms and is significantly decreased with age and in particular is significantly decreased in the aged female. more...

Organism:: Oryctolagus cuniculus

Type:: Expression profiling by array

Platform:: GPL13758
21 Samples

Download data: GPR

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Accession:: GSE30261

ID:: 200030261

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000301942.

Rabbit heart gene expression in Left ventricle (LV) following banding of the descending thoracic aorta (AOB-LV) vs Sham-control LV and in Right ventricle (RV) following banding the pulmonary artery (PAB-RV) vs. Sham-control RV

(Submitter supplied) Background: Right ventricular (RV) and left ventricular (LV) myocardium differ in their response to pressure-overload hypertrophy (POH). In this report we use microarray and proteomic analyses to identify pathways modulated by LV-, and RV-POH in the immature heart. Methods: Newborn New Zealand White rabbits underwent banding of the descending thoracic aorta (LV-POH; n=6). RV-POH was achieved by banding the pulmonary artery (n=6). more...