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Items: 7

1.

EFFECT OF ORAL UREA ADMINISTRATION ON THE TRANSCRIPTOME OF THE EQUINE ENDOMETRIUM AND EMBRYO

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24409 GPL21401
24 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE133974
ID:
200133974
2.

EFFECT OF ORAL UREA ADMINISTRATION ON THE TRANSCRIPTOME OF THE EQUINE EMBRYO

(Submitter supplied) The effects of a high BUN on blastocoele fluid urea concentrations and analyzed the transcriptome of day-14 equine embryos based upon RNA sequencing.
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
12 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE133972
ID:
200133972
3.

Differential Gene Expression Analysis Reveals Pathways Important in Early Post-Traumatic Osteoarthritis in an Equine Model

(Submitter supplied) Objective: To quantify gene expression changes in the synovium of osteoarthritis-affected joints in an equine metacarpophalangeal joint (MCPJ) chip model specifically designed to recapitulate early post-traumatic osteoarthritis (PTOA). Design: Synovial samples were collected arthroscopically from the MCPJ of 11 adult horses before (pre-OA) and after (OA) surgical induction of osteoarthritis and from sham-operated joints. more...
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
28 Samples
Download data: TXT
Series
Accession:
GSE144031
ID:
200144031
4.

Differential gene expression in articular cartilage and subchondral bone of neonatal and adult horses

(Submitter supplied) We report differential expression analysis of RNAseq data in joint-related tissues (articular cartilage and subchondral bone) in healthy foals (4 weeks of age or younger) and healthy adult horses. We find that 1115 genes are differentially expressed in cartilage and 3574 in bone between these two groups. Functional annotation suggests that differences primarily lie in genes involved in growth/turnover of tissue and cell signaling.
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21941 GPL24409 GPL15545
56 Samples
Download data: TXT
Series
Accession:
GSE135322
ID:
200135322
5.

Characterization of the Placental Transcriptome through Mid to Late Gestation in the Mare

(Submitter supplied) The placenta is a dynamic organ which undergoes extensive remodeling throughout pregnancy to support, protect and nourish the developing fetus. Despite the importance of the placenta, very little is known about its gene expression beyond very early pregnancy and post-partum. Therefore, we utilized RNA-sequencing to characterize the transcriptome from the fetal (chorioallantois) and maternal (endometrium) components of the placenta from mares throughout gestation (4, 6, 10, 11 m). more...
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
15 Samples
Download data: XLSX
Series
Accession:
GSE136691
ID:
200136691
6.

A high protein model alters the endometrial transcriptome of mares

(Submitter supplied) We developed an experimental model to elevate BUN during diestrus. There were both urea and control treatments (7 mares/treatment), done in a crossover design. Urea treatment consisted of a loading dose of urea (0.03 g/kg of urea) and urea injections over 6 hours (0.03 g/kg/hr). Control mares received the same volume of saline solution. Blood samples were collected to measure BUN. Uterine and vaginal pH were evaluated after the last intravenous infusion, then endometrial biopsies were collected for RNA-sequencing
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
14 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE131810
ID:
200131810
7.

Evaluation of mRNA expression in the equine chorioallantoic membrane

(Submitter supplied) Purpose:The goal of this study was to evalute gene expression patterns of equine chorioallantoic membrane during different stages of the pregnancy Method: mRNA profile of equine chorioallantoic membrane (CAM) from 45days, 4months, 6months and 10months (4 samples for each time points) generated by RNA-sequencing,using a Illumina HiSeq 4000 ( HiSeq 4000 sequencing kit version 1). The sequence reads were trimmed for adapters and quality using TrimGalore Version 0.4.4,and then mapped to EquCab2.0 using STAR-2.5.2b. more...
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
16 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE108279
ID:
200108279
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