GPL2829[RGSE] - GEO DataSets

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Items: 3

Select item 2000078831.

Expression profile of peripheral blood of healthy individuals phenotyped based on “Prakriti” concept of Ayurveda

(Submitter supplied) Immense phenotypic variability exists among healthy individuals which is a consequence of both genetic and environmental effects. Genome wide expression variability is a powerful tool for capturing these expression variations and hence can give insights into genotype phenotype correlations. In the ancient Indian system of medicine, of Ayurveda, the basic tenet for treatment relies on phenotypic assessment In this system, assessment of predisposition, susceptibility or prognosis for disease is based on the phenotypic assessment of the individual. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
108 Samples

Download data: GPR

Series

Accession:: GSE7883

ID:: 200007883

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000033122.

Expression Changes Relevant for Apoptosis in K562 Cells Co-Treated with Amifostine and Imatinib

(Submitter supplied) We had previously demonstrated an increased proapoptotic effect of Imatinib (STI571) in combination with Amifostine (AMI) in K562 cell line. In this study we used genomic scale gene expression profiling to monitor changes at transcriptional level in K562 cells during the treatment with AMI+STI571. We identified a transcriptional repressor of survival genes, known as BTF, which triggers a pro-apoptotic signal, potentially helpful to overcome the resistance to STI571. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
4 Samples

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Series

Accession:: GSE3312

ID:: 200003312

Select item 2000032943.

Comparative study of gene expression in human colorectal cancer tissues and normal mucosa

(Submitter supplied) The purpose of our study was to better understand the genetic mechanism of oncogenesis for human colorectal cancer and to identify potential new tumour markers of use in clinical practice. Results: Comparing cancerous tissues with normal colonic mucosa we identified 584 known genes (3%) differentially expressed to a significant degree (p<0.001). Many of the transcripts that were more abundant in tumours than in non-neoplastic tissues appear to reflect important events for colon carcinogenesis. more...