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Robust induction of primordial germ cells of white rhinoceros on the brink of extinction

(Submitter supplied) In vitro gametogenesis, the process of generating gametes from pluripotent cells in culture, is a powerful tool for improving our understanding of germ cell development as well as an alternative source of gametes.(1) Conservation of the northern white rhinoceros (NWR), a species for which only two females remain, would be a compelling application of in vitro gametogenesis as a gametes source. Here, we established a culture system that induces a robust number of primordial germ cell-like cells (PGCLCs) from pluripotent stem cells of the NWR and southern white rhinoceros (SWR), the closest species to the NWR. more...
Organism:
Ceratotherium simum simum; Ceratotherium simum cottoni
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL31181 GPL31180
26 Samples
Download data: TXT
Series
Accession:
GSE193166
ID:
200193166

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