GPL32911[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2002201111.

Anti-HIV-1 CAR-T cells armed with autogenic broadly neutralizing antibody and follicle-homing receptor CXCR5 ar effective against different HIV-1 clades and reduce viral reservoir in HIV-1-infected individuals

(Submitter supplied) Chimeric antigen receptor T (CAR-T) cells, long proposed for HIV-1 treatment, has yet to achieve desirable therapeutic efficacy. In our study, M10 CAR-T cells were used for treating 18 HIV-1 patients via a regimen combining two M10 infusions and repeat chidamide stimulation for HIV reservoir activation. Consequently, 74.3% of M10 infusions resulted in significant suppression of viral rebound (averaging 77.4% decline), with 10 patients showing persistently reduced cell-associated HIV-1 RNA levels (averaging > 1.15 log10) over the 150-day observation period. more...

Organism:: Human immunodeficiency virus 1

Type:: Other

Platforms:: GPL32911 GPL32910
26 Samples

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Series

Accession:: GSE220111

ID:: 200220111

Select item 1000329112.

sequel (Human immunodeficiency virus 1)

Organism:: Human immunodeficiency virus 1

1 Series
2 Samples

Platform

Accession:: GPL32911

ID:: 100032911

Select item 3067885493.

Organism:: Human immunodeficiency virus 1

Source name:: peripheral blood

Platform:: GPL32911
Series:: GSE220111

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Sample

Accession:: GSM6788549

ID:: 306788549

SRA Run Selector

Select item 3067885484.

Organism:: Human immunodeficiency virus 1

Source name:: peripheral blood

Platform:: GPL32911
Series:: GSE220111

Download data: FA, TXT

Sample

Accession:: GSM6788548

ID:: 306788548

SRA Run Selector

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