GPL33896[RGSE] - GEO DataSets

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Items: 4

Select item 2002554071.

Single cell approaches define two mammalian oligodendrocyte precursor cell populations and their evolution over developmental time [Xenium In Situ Gene Expression]

(Submitter supplied) Here, we have used single-cell RNA sequencing (scRNA-seq), single-cell ATAC sequencing (scATAC-seq) and spatial transcriptomics to characterize murine cortical OPCs throughout postnatal life. During development, we identify two differentially-localized PDGFRα-positive OPC populations that are transcriptionally and epigenetically distinct. One population (active or actOPCs) is metabolically active and is enriched in white matter. more...

Organism:: Mus musculus

Type:: Other

Platform:: GPL33896
3 Samples

Download data: CSV, JSON, MTX, TIFF, TSV

Series

Accession:: GSE255407

ID:: 200255407

PubMed Full text in PMC Similar studies

Select item 2002559532.

Transcriptomic landscape of the anterior thalamic nuclei of the mouse [Xenium]

(Submitter supplied) Here, we examined diversity in the cell-type composition of the mouse anterior thalamic nuclei (ATN) using single-cell RNA-seq and single-cell spatial transcriptomics.

Organism:: Mus musculus

Type:: Other

Platform:: GPL33896
7 Samples

Download data: RDS, TAR, TXT

Series

Accession:: GSE255953

ID:: 200255953

PubMed Similar studies

Select item 2002540873.

Postnatal Subventricular Zone Injury Predicts Motor Impairment in Preterm Infants Following Intestinal Disease

(Submitter supplied) Following intestinal perforation in neonatal mice there is an injury to the subventrcular zone stem cell niche. These files are the raw data from mouse brain sections, transecting SVZ in controls and mice with modeled instestinal perforation.

Organism:: Mus musculus

Type:: Other

Platform:: GPL33896
2 Samples

Download data: CSV, JSON, MTX, TSV, ZIP

Series

Accession:: GSE254087

ID:: 200254087

Select item 2002465844.

Ataxia-telangiectasia mutated (Atm) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy

(Submitter supplied) Diffuse midline gliomas (DMGs) are lethal brain tumors characterized by inactivating p53 mutations and oncohistone H3.3K27M mutations that rewire the cellular response to genotoxic stress, presenting therapeutic opportunities. We used RCAS/tv-a retroviruses and Cre recombinase to inactivate p53 and induce K27M in the native H3f3a allele in a lineage- and spatially-directed manner, yielding primary mouse DMGs. more...