GEO DataSets

(Submitter supplied) RNA interactome studies have revealed that hundreds of zinc finger proteins (ZFPs) are candidate RNA-binding proteins (RBPs), despite being annotated as DNA-interacting transcription factors. The RNA substrates of ZFPs and the functional significance of their potential roles as DNA- and RNA-binding proteins (DRBPs) remain largely uncharacterized. Here we present a systematic multi-omics analysis of the DNA and RNA binding targets and regulatory roles of more than 100 ZFPs representing 37 zinc finger families. more...

Organism:

synthetic construct

Type:

Other

Platform:

GPL34014

4 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

synthetic construct; Homo sapiens

Type:

Other; Expression profiling by high throughput sequencing

Platforms:

GPL34014 GPL24676

630 Samples

Download data: NARROWPEAK, SF, TSV, TXT

(Submitter supplied) While various methods exist for examining and visualizing the structure of RNA molecules, dimethyl sulfate-mutational profiling and sequencing (DMS-MaPseq) stands out for its simplicity and versatility. This technique has proven effective for studying RNA structures both in vitro and in complex biological settings. We've updated the protocol for using DMS-MaPseq, and it can also be employed to identify the binding of antisense oligonucleotides (ASOs) to RNA. more...

Organism:

synthetic construct

Type:

Other

Platforms:

GPL32483 GPL34014

13 Samples

Download data: CSV