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EGF treated SCN versus intra-animal control at two circadian times

(Submitter supplied) Background: Identifying the gene regulatory networks governing physiological signal integration remains an important challenge in circadian biology. Epidermal growth factor receptor (EGFR) has been implicated in circadian function and EGFR is expressed in the suprachiasmatic nucleus (SCN), the core circadian pacemaker. The transcription networks downstream of EGFR in the SCN are unknown, but by analogy to other SCN inputs we expect the response to EGFR activation to depend on circadian timing and thus be “circadian context–dependent”. more...
Organism:
Rattus norvegicus; synthetic construct
Type:
Expression profiling by array
Platform:
GPL3446
8 Samples
Download data
Series
Accession:
GSE4245
ID:
200004245

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