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Items: 4

1.

Genome level identification of direct Ubx targets from third-instar imaginal discs

(Submitter supplied) Hox proteins are transcription factors and key regulators of segmental identity along the anterior posterior axis across all bilateral animals. Despite decades of research, mechanism by which Hox proteins select their targets and specify segmental identity remains elusive. To address this question we carried out whole genome ChIP-chip experiments to identify direct targets of Hox protein Ultrabithorax (Ubx) during haltere development in Drosophila. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL4149 GPL4150
6 Samples
Download data: TXT
Series
Accession:
GSE28778
ID:
200028778
2.

Whole-genome analysis reveals active heat shock factor binding sites are mostly associated with non-heat shock genes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array; Expression profiling by array
5 related Platforms
27 Samples
Download data: CALLS, PAIR, TXT
Series
Accession:
GSE19746
ID:
200019746
3.

Whole-genome analysis of heat shock factor binding sites in Drosophila melanogaster during heat shock

(Submitter supplied) Whole-genome analysis of heat shock factor binding sites in Drosophila melanogaster. Heat shock factor IP DNA or Mock IP DNA from heat shocked Kc 167 cells compared to whole cell extract on Agilent 2x244k tiling arrays.
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL4149 GPL4150
7 Samples
Download data: TXT
Series
Accession:
GSE19744
ID:
200019744
4.

RNA polymerase is poised for activation across the genome

(Submitter supplied) Regulation of gene expression is integral to the development and survival of all organisms. Transcription begins with the assembly of a pre-initiation complex at the gene promoter, followed by initiation of RNA synthesis and the transition to productive elongation. In many cases, recruitment of RNA polymerase II (Pol II) to a promoter is necessary and sufficient for activation of gene. However, there are a few notable exceptions to this paradigm, including heat shock genes and several proto-oncogenes, whose expression is attenuated by regulated stalling of polymerase elongation within the promoter-proximal region. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array; Genome binding/occupancy profiling by genome tiling array
5 related Platforms
29 Samples
Download data: CEL, TIFF, TXT
Series
Accession:
GSE6714
ID:
200006714
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