GEO DataSets

(Submitter supplied) The crypt-villus axis represents the essential unit of the small intestine, which integrity and functions are fundamental to assure tissue and whole-body homeostasis. Disruption of pathways regulating the fine balance between proliferation and differentiation results in diseases development. Nowadays, it is well established that microRNAs (miRNAs) play a crucial role in the homeostasis maintenance and perturbation of their levels may promote tumor development. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

20 Samples

Download data: TXT

(Submitter supplied) The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ coactivators (PGC-1s) are transcriptional key players of liver metabolism, able to regulate mitochondrial function, gluconeogenesis and lipid metabolism. Their activity is accurately modulated by post-translational modifications. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

11 Samples

Download data: TXT

(Submitter supplied) The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ coactivators (PGC-1s) are transcriptional key players of liver metabolism, able to regulate mitochondrial function, gluconeogenesis and lipid metabolism. Their activity is accurately modulated by post-translational modifications. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

10 Samples

Download data: TXT

(Submitter supplied) The present study focuses on the identification of differentially regulated microRNAs in Calsarcin-1 knockout mice, which shows dilated cardiomyopathy phenotype.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

8 Samples

Download data: IDAT, XLSX

(Submitter supplied) Recently, we showed that disturbed flow caused by a partial ligation ofmouse carotid artery rapidly induces atherosclerosis. Analysis of mechanosenstive microRNA in the mouse carotid endothelium. In this study, we examined the microRNAs that respond differentially to blood flow pattern in the mouse carotid endothelium. We surgically induced disturbed blood flow in the left common carotid cartery (LCA) using partial carotid ligation surgery while the right carotid artery was left undisturbed. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL8181

24 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL8181 GPL6885

16 Samples

Download data

(Submitter supplied) In this study, miRNA expression profiles were examined by Illumina microarray in mouse embryonic stem cells (ESCs) derived from androgenetic (aESC), parthenogenetic (pESC) and fertilized (fESC) blastocysts. Results showed that 125, 42 and 99 miRNAs were differentially expressed in the aESCs vs. fESCs, pESCs vs. fESCs and aESCs vs. pESCs, respectively.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

8 Samples

Download data: TXT

(Submitter supplied) MicroRNA is essential for the process of spermatogonesis, however analysis of its change in expression within germ cells during this process has been limited. We set out to examine the change in the miRNA expression profile of highly enriched mouse germ cell populations in vairous developmental stages.These inlcuded postnatal gonocytes, day 7-9 spermatogonia as well as pachytene spermatocytes and round spermatids from adult mice

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

12 Samples

Download data: TXT, XLS

(Submitter supplied) Dendritic cells (DCs) are the most potent antigen (Ag)-presenting cells. Whereas immature DCs down-regulate T cell responses to induce/maintain immunological tolerance, mature DCs promote immunity. To amplify their functions, DCs communicate with neighboring DCs through soluble mediators, cell-to-cell contact and vesicle exchange. Transfer of nanovesicles (<100nm) derived from the endocytic pathway (termed exosomes) represents a novel mechanism of DC-to-DC communication. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL8181

12 Samples

Download data