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Items: 2

1.

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
4 related Platforms
61 Samples
Download data: TXT
Series
Accession:
GSE19492
ID:
200019492

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Transcriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS)

(Submitter supplied) Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agonist, LPS. Using a custom platform permitting cross-species interrogation coupled with deep sequencing of mRNA 5’ ends, we identified extensive divergence in LPS-regulated orthologous gene expression between humans and mice (24% of orthologs, http://www.macgate.qfab.org). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL9801
16 Samples
Download data: TXT
Series
Accession:
GSE19482
ID:
200019482

PubMed Full text in PMC Similar studies Analyze with GEO2R

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db=gds|term=GPL9801[RGSE]|query=27|qty=3|blobid=MCID_6735044eb31eac71f54134fb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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