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Items: 5

1.

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer

(Submitter supplied) Complex regulatory networks control epithelial-to-mesenchymal transition (EMT) but the underlying epigenetic control is poorly understood. Lysine-specific demethylase 1 (LSD1) is a key histone demethylase that alters the epigenetic landscape. Here we explored the role of LSD1 in global epigenetic regulation of EMT, cancer stem cells (CSCs), the tumour microenvironment, and therapeutic resistance in breast cancer. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
3 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE104754
ID:
200104754
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

MDAMB231_LSD_ChIP

Organism:
Homo sapiens
Source name:
MDA-MB-231 cell line
Platform:
GPL18573
Series:
GSE104754 GSE104755
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2807189
ID:
302807189
4.

MCF7_PMA_TGF_LSD1_ChIP

Organism:
Homo sapiens
Source name:
MCF7 cell line
Platform:
GPL18573
Series:
GSE104754 GSE104755
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2807188
ID:
302807188
5.

MCF7_NS_LSD1_ChIP

Organism:
Homo sapiens
Source name:
MCF7 cell line
Platform:
GPL18573
Series:
GSE104754 GSE104755
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2807187
ID:
302807187
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Supplemental Content

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