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Items: 12

1.

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

(Submitter supplied) Foxp3+ regulatory T (Treg) cells are essential for immunological tolerance and homeostasis. In peripheral tissues, Treg cells acquire enhanced suppressive functions and co-opt distinct transcriptional modules, allowing context and tissue-dependent immune regulation. Here we show that the transcription factor c-Maf was highly expressed by effector Treg cells and controlled their IL-10 production. In the intestine, c-Maf was required for the differentiation of RORgt+ microbiota-dependent Treg cells, and restricted their production of inflammatory cytokines. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
10 Samples
Download data: TXT
Series
Accession:
GSE106396
ID:
200106396
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

S495KO3Spl

Organism:
Mus musculus
Source name:
KO_Spleen Rep3
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837110
ID:
302837110
4.

S495KO3Gut

Organism:
Mus musculus
Source name:
KO_Gut Rep3
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837109
ID:
302837109
5.

S453KO2Spl

Organism:
Mus musculus
Source name:
KO_Spleen Rep2
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837108
ID:
302837108
6.

S453KO2Gut

Organism:
Mus musculus
Source name:
KO_Gut Rep2
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837107
ID:
302837107
7.

S433WT3Spl

Organism:
Mus musculus
Source name:
WT_Spleen Rep3
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837106
ID:
302837106
8.

S433WT3Gut

Organism:
Mus musculus
Source name:
WT_Gut Rep3
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837105
ID:
302837105
9.

S398WT2Spl

Organism:
Mus musculus
Source name:
WT_Spleen Rep2
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837104
ID:
302837104
10.

S371WT1Spl

Organism:
Mus musculus
Source name:
WT_Spleen Rep1
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837103
ID:
302837103
11.

S371WT1Gut

Organism:
Mus musculus
Source name:
WT_Gut Rep1
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837102
ID:
302837102
12.

S366KO1Spl

Organism:
Mus musculus
Source name:
KO_Spleen Rep1
Platform:
GPL19057
Series:
GSE106396
Download data: TXT
Sample
Accession:
GSM2837101
ID:
302837101
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Supplemental Content

db=gds|term=GSE106396[Accession]|query=1|qty=2|blobid=MCID_668764cf097f457047706cec|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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