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Items: 4

1.

Genome-wide chromatin analysis of Ewing sarcoma (ChIP-seq)

(Submitter supplied) As the second most common malignant bone tumor in children and adolescents, Ewing sarcoma is initiated and exacerbated by a chimeric oncoprotein, most commonly, EWS-FLI1. In this study, we apply epigenomic analysis to characterize the transcription dysregulation in this cancer, focusing on the investigation of super-enhancer and its associated transcriptional regulatory mechanisms. We demonstrate that super-enhancer-associated transcripts are significantly enriched in EWS-FLI1 target genes, contribute to the aberrant transcriptional network of the disease, and mediate the exceptional sensitivity of Ewing sarcoma to transcriptional inhibition. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21290
2 Samples
Download data: BW
Series
Accession:
GSE109477
ID:
200109477

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 3000 (Homo sapiens)

Organism:
Homo sapiens
1138 Series
28241 Samples
Download data
Platform
Accession:
GPL21290
ID:
100021290

3.

A673_Input_DNA

Organism:
Homo sapiens
Source name:
Ewing sarcoma cells
Platform:
GPL21290
Series:
GSE109477
Download data
Sample
Accession:
GSM2944109
ID:
302944109

SRA Run Selector

4.

A673_MEIS1_ChIP-seq

Organism:
Homo sapiens
Source name:
Ewing sarcoma cells
Platform:
GPL21290
Series:
GSE109477
Download data: BW
Sample
Accession:
GSM2944108
ID:
302944108

SRA Run Selector

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db=gds|term=GSE109477[Accession]|query=14|qty=2|blobid=MCID_672eba5f6fe43f52cd5a9ff9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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